3-hydroxy-N’-(1,3-dimethylbutylidene)-2-naphthoic acid hydrazide | 214417-91-1

• 物质功能分类: 化学试剂 - 有机试剂 - 多环化合物
• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 3-hydroxy-N’-(1,3-dimethylbutylidene)-2-naphthoic acid hydrazide
• 英文别名: 3-hydroxy-N-(4-methylpentan-2-ylideneamino)naphthalene-2-carboxamide
• CAS: 214417-91-1
• 化学式: C₁₇H₂₀N₂O₂
• 分子量: 284.358
• InChiKey: HPTJCEPNQHYWIH-UHFFFAOYSA-N

物化性质

• 密度：
  1.13±0.1 g/cm3(Predicted)
• LogP：
  1.7 at 20℃

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  21
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  61.7
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  3-hydroxy-N’-(1,3-dimethylbutylidene)-2-naphthoic acid hydrazide 、 nickel(II) nitrate 在 sodium hydroxide 作用下， 以 水 、 N,N-二甲基甲酰胺 为溶剂， 生成
  参考文献：
  名称：

  A new acylhydrazine N'-(1,3 dimethylbutylene)-3-hydroxy-naphthohydrazide based fluorescent sensor for the detection of Ni2+

  摘要：

  In this paper, a novel hydrazide compound (N'-(1,3 dimethylbutylene)-3-hydroxy-naphthohydrazide) (BMH) was synthesized by a simple three-stage reaction and its chemical structure was confirmed by H-1 NMR, C-13 NMR and FTIR characterization. This compound was used as fluorescent sensor for the detection of Ni2+ based on photoluminescence quenching. The fluorescence quenching of BMH upon the addition of Ni2+ is due to the formation of coordination complex which was verified by bind model and density functional theory studies. The Ni2+ concentration dependent fluorescence quenching efficiency of BMH was examined and the detection conditions were optimized. There is a good linear relationship between the emission intensity quenching (Delta F = F-0-F) and the Ni2+ concentration (c) between 80 nM and 2 mu M and the detection limit is 60 nM. The simple preparation of the compound BMH and the high sensitivity of the fluorescent sensor hold great promise for the determination of Ni2+ in environment.

  DOI：

  10.1016/j.dyepig.2020.108582
• 作为产物：
  描述：

  2-羟基-3-萘甲酸 在 硫酸 、 一水合肼 作用下， 以 乙醇 为溶剂， 反应 15.0h， 生成 3-hydroxy-N’-(1,3-dimethylbutylidene)-2-naphthoic acid hydrazide
  参考文献：
  名称：

  A new acylhydrazine N'-(1,3 dimethylbutylene)-3-hydroxy-naphthohydrazide based fluorescent sensor for the detection of Ni2+

  摘要：

  In this paper, a novel hydrazide compound (N'-(1,3 dimethylbutylene)-3-hydroxy-naphthohydrazide) (BMH) was synthesized by a simple three-stage reaction and its chemical structure was confirmed by H-1 NMR, C-13 NMR and FTIR characterization. This compound was used as fluorescent sensor for the detection of Ni2+ based on photoluminescence quenching. The fluorescence quenching of BMH upon the addition of Ni2+ is due to the formation of coordination complex which was verified by bind model and density functional theory studies. The Ni2+ concentration dependent fluorescence quenching efficiency of BMH was examined and the detection conditions were optimized. There is a good linear relationship between the emission intensity quenching (Delta F = F-0-F) and the Ni2+ concentration (c) between 80 nM and 2 mu M and the detection limit is 60 nM. The simple preparation of the compound BMH and the high sensitivity of the fluorescent sensor hold great promise for the determination of Ni2+ in environment.

  DOI：

  10.1016/j.dyepig.2020.108582

文献信息

• Hydrazone derivatives
  申请人：Otsuka Chemical Holdings Co., Ltd.

  公开号：EP1420044B1

  公开（公告）日：2006-09-06
• CRYSTALS AND PRODUCTION METHOD FOR THE SAME
  申请人：OTSUKA CHEMICAL CO., LTD.

  公开号：US20230022116A1

  公开（公告）日：2023-01-26

  An object of the present invention is to provide novel crystals. Provided are crystals of 3-hydroxy-N′-(1,3-dimethylbutylidene)-2-naphthoic acid hydrazide having an X-ray powder diffraction pattern comprising a peak of maximum intensity at an angle of diffraction (2θ) of 6.1±0.2°.
• ヒドラジド化合物の亜鉛錯体、及びゴム用加硫戻り抑制剤
  申请人：大塚化学株式会社

  公开号：JP2023048561A

  公开（公告）日：2023-04-07

  【課題】本発明の目的は、ゴム組成物に添加するヒドラジド化合物の亜鉛錯体、及びこのヒドラジド化合物の亜鉛錯体を含むゴム用加硫戻り抑制剤を提供する事である。【解決手段】ヒドラジド化合物の亜鉛錯体、及びヒドラジド化合物の亜鉛錯体を含むゴム用加硫戻り抑制剤。【選択図】なし
• A new acylhydrazine N'-(1,3 dimethylbutylene)-3-hydroxy-naphthohydrazide based fluorescent sensor for the detection of Ni2+
  作者：Mengqin Liu、Zipeng Yin、Yuxing Tan、Junhua Li、Hui Peng、Abing Duan、Chunhua Luo

  DOI：10.1016/j.dyepig.2020.108582

  日期：2020.10

  In this paper, a novel hydrazide compound (N'-(1,3 dimethylbutylene)-3-hydroxy-naphthohydrazide) (BMH) was synthesized by a simple three-stage reaction and its chemical structure was confirmed by H-1 NMR, C-13 NMR and FTIR characterization. This compound was used as fluorescent sensor for the detection of Ni2+ based on photoluminescence quenching. The fluorescence quenching of BMH upon the addition of Ni2+ is due to the formation of coordination complex which was verified by bind model and density functional theory studies. The Ni2+ concentration dependent fluorescence quenching efficiency of BMH was examined and the detection conditions were optimized. There is a good linear relationship between the emission intensity quenching (Delta F = F-0-F) and the Ni2+ concentration (c) between 80 nM and 2 mu M and the detection limit is 60 nM. The simple preparation of the compound BMH and the high sensitivity of the fluorescent sensor hold great promise for the determination of Ni2+ in environment.