cyclandelate

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: cyclandelate
• 英文别名: (3,3,5-trimethylcyclohexyl) (2R)-2-hydroxy-2-phenylacetate
• 化学式: C₁₇H₂₄O₃
• 分子量: 276.376
• InChiKey: WZHCOOQXZCIUNC-PESDSKBTSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.2
• 重原子数：
  20
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.59
• 拓扑面积：
  46.5
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  3,3,5-三甲基环己醇 、 D-扁桃酸 在 zirconocene bis(perfluorooctanesulfonate) trihydrate*(tetrahydrofuran) 作用下， 以 neat (no solvent) 为溶剂， 以70%的产率得到cyclandelate
  参考文献：
  名称：

  无溶剂条件下锆茂催化的脂肪酸（酯）和醇以1：1的比例进行直接（反式）酯化反应

  摘要：

  使用锆茂配合物（1，1 mol％），具有良好耐水性的强路易斯酸作为溶剂下的催化剂，以严格的1：1比例直接进行酰基酸（酯）和醇的直接（酯交换）酯化反应的高效方法。自由状态已经发展。各种各样的酸和醇（酯）底物经过（酯交换）酯化反应，以中等到良好或优异的产率产生羧酸酯基序，并具有良好的功能耐受性，例如对C–Br以及C = C和C≡C债券。配合物1可以循环测试六次，而不会显示出催化效率的显着下降。已证明，用于治疗高血压以及心脏和血管疾病的环芳铁酸盐可以使用复杂的1.功能耐受性，以克级直接合成，收率为81％（6.70 g）。例如对C–Br的键以及C = C和C≡C键。配合物1可以循环测试六次，而不会显示出催化效率的显着下降。已证明，用于治疗高血压以及心脏和血管疾病的环芳铁酸盐可以使用复合物1以克级直接合成，收率为81％（6.70 g）。

  DOI：

  10.1039/c7gc02174g

文献信息

• TEMPERATURE DETECTION INK, TEMPERATURE DETECTION INK INITIALIZATION METHOD, TEMPERATURE INDICATOR, AND ARTICLE MANAGEMENT SYSTEM
  申请人：HITACHI INDUSTRIAL EQUIPMENT SYSTEMS CO., LTD.

  公开号：EP3745106A1

  公开（公告）日：2020-12-02

  It is possible to provide a temperature detection ink, which allows color initialization by a simple method and discolors with addition of time and temperature at a reaction temperature or higher. To solve the problem, the temperature detection ink according to the present invention includes a temperature detection material and a solvent. The temperature detection material has a structure in which a thermosensitive material containing a leuco dye, a color-developing agent, and a decolorant is contained in a microcapsule, or a structure in which a phase containing the thermosensitive material is phase-separated from a matrix material. The thermosensitive material is solidified while being decolored by cooling from a molten state to a glass transition temperature or lower at a predetermined rate or higher. The thermosensitive material has a glass transition temperature of -20 to 60°C, and a melting point that is 60 to 250°C and lower than the boiling point of the solvent.

  有可能提供一种温度检测墨水，它可以通过简单的方法初始化颜色，并在反应温度或更高的温度下随着时间和温度的增加而褪色。为了解决这个问题，本发明的温度检测墨水包括温度检测材料和溶剂。温度检测材料的结构是在微胶囊中含有一种热敏材料，其中包含一种白兰地染料、一种显色剂和一种脱色剂，或者是含有热敏材料的相与基体材料相分离的结构。在脱色过程中，热敏材料以预定或更高的速度从熔融状态冷却到玻璃化转变温度或更低的温度，从而固化。热敏材料的玻璃化温度为-20 至 60°C，熔点为 60 至 250°C，低于溶剂的沸点。
• New process for preparing cis-3,3,5-trimethylcyclohexyl-D,L-alpha-(3-pyridinecarboxy)-phenylacetate
  申请人：RAVIZZA S.p.A.

  公开号：EP0157151B1

  公开（公告）日：1988-07-13
• JPS5481240A
  申请人：——

  公开号：JPS5481240A

  公开（公告）日：1979-06-28
• JPS6168407A
  申请人：——

  公开号：JPS6168407A

  公开（公告）日：1986-04-08
• Temperature Detection Ink, Temperature Detection Ink Initialization Method, Temperature Indicator, and Article Management System
  申请人：Hitachi Industrial Equipment Systems Co., Ltd.

  公开号：US20210063252A1

  公开（公告）日：2021-03-04

  It is possible to provide a temperature detection ink, which allows color initialization by a simple method and discolors with addition of time and temperature at a reaction temperature or higher. To solve the problem, the temperature detection ink according to the present invention includes a temperature detection material and a solvent. The temperature detection material has a structure in which a thermosensitive material containing a leuco dye, a color-developing agent, and a decolorant is contained in a microcapsule, or a structure in which a phase containing the thermosensitive material is phase-separated from a matrix material. The thermosensitive material is solidified while being decolored by cooling from a molten state to a glass transition temperature or lower at a predetermined rate or higher. The thermosensitive material has a glass transition temperature of −20 to 60° C., and a melting point that is 60 to 250° C. and lower than the boiling point of the solvent.