S-[4-(2-naphthyloxy)but-1-yl] n-dodecyldithiocarbamate

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: S-[4-(2-naphthyloxy)but-1-yl] n-dodecyldithiocarbamate
• 英文别名: 4-naphthalen-2-yloxybutyl N-dodecylcarbamodithioate
• 化学式: C₂₇H₄₁NOS₂
• 分子量: 459.761
• InChiKey: SAWGVNBCSUGCHJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  10.3
• 重原子数：
  31
• 可旋转键数：
  18
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.59
• 拓扑面积：
  78.6
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  二硫化碳 、 十二烷基伯胺 、 2-(4-氯丁氧基)萘 在 苄基三甲基氢氧化铵 作用下， 以 二甲基亚砜 为溶剂， 反应 3.33h， 以98%的产率得到S-[4-(2-naphthyloxy)but-1-yl] n-dodecyldithiocarbamate
  参考文献：
  名称：

  Triton-B Catalyzed Efficient One-Pot Synthesis of Dithiocarbamate Esters

  摘要：

  A novel process for the one-step chemoselective conversion of alkyl halides into dithiocarbamates as protected amines was developed using benzyltrimethylammonium hydroxide (Triton-B) in presence of carbon disulfide. Thus, dithiocarbamates of different amines were prepared in very good to excellent yields. This protocol is mild, chemoselective, and efficient compared to other methods.

  DOI：

  10.1007/s00706-006-0438-8

文献信息

• Triton-B Catalyzed Efficient One-Pot Synthesis of Dithiocarbamate Esters
  作者：Devdutt Chaturvedi、Suprabhat Ray

  DOI：10.1007/s00706-006-0438-8

  日期：2006.3

  A novel process for the one-step chemoselective conversion of alkyl halides into dithiocarbamates as protected amines was developed using benzyltrimethylammonium hydroxide (Triton-B) in presence of carbon disulfide. Thus, dithiocarbamates of different amines were prepared in very good to excellent yields. This protocol is mild, chemoselective, and efficient compared to other methods.