[4-(2-naphthyloxy)but-1-yl] n-dodecyl-carbamate

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: [4-(2-naphthyloxy)but-1-yl] n-dodecyl-carbamate
• 英文别名: 4-naphthalen-2-yloxybutyl N-dodecylcarbamate
• 化学式: C₂₇H₄₁NO₃
• 分子量: 427.627
• InChiKey: DAPKFZMKAIZTGI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  9.2
• 重原子数：
  31
• 可旋转键数：
  18
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.59
• 拓扑面积：
  47.6
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  十二烷基伯胺 、 二氧化碳 、 2-(4-氯丁氧基)萘 在 苄基三甲基氢氧化铵 作用下， 以 二甲基亚砜 为溶剂， 反应 3.5h， 以98%的产率得到[4-(2-naphthyloxy)but-1-yl] n-dodecyl-carbamate
  参考文献：
  名称：

  A High Yielding, One-Pot, Triton-B Catalyzed, Expeditious Synthesis of Carbamate Esters by Four Component Coupling Methodology

  摘要：

  A novel process for the one-step chemoselective conversion of alkyl halides into carbamates as protected amines was developed using benzyltrimethylammonium hydroxide (Triton-B) in presence of gaseous carbon dioxide. Thus, carbamate esters of different amines were prepared in very good to excellent yields.

  DOI：

  10.1007/s00706-005-0417-5

文献信息

• A High Yielding, One-Pot, Triton-B Catalyzed, Expeditious Synthesis of Carbamate Esters by Four Component Coupling Methodology
  作者：Devdutt Chaturvedi、S. Ray

  DOI：10.1007/s00706-005-0417-5

  日期：2006.2

  A novel process for the one-step chemoselective conversion of alkyl halides into carbamates as protected amines was developed using benzyltrimethylammonium hydroxide (Triton-B) in presence of gaseous carbon dioxide. Thus, carbamate esters of different amines were prepared in very good to excellent yields.