N-isopropyl-2-methyl-N-phenylaniline

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: N-isopropyl-2-methyl-N-phenylaniline
• 英文别名: 2-methyl-N-phenyl-N-propan-2-ylaniline
• 化学式: C₁₆H₁₉N
• 分子量: 225.334
• InChiKey: HBYPIKGOVDTBKL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.8
• 重原子数：
  17
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  3.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  2-溴甲苯 、 N-异丙基苯胺 在 di-μ-bromobis(tri-tert-butylphosphine)dipalladium(I) 、 sodium t-butanolate 作用下， 以 甲苯 为溶剂， 以51%的产率得到N-isopropyl-2-methyl-N-phenylaniline
  参考文献：
  名称：

  使用钯（I）三叔丁基膦溴化二聚体，钯与受阻的N-烷基取代的苯胺催化芳基溴化的胺化反应。

  摘要：

  描述了使用Pd（OAc）（2）和P（t-Bu）（3）或钯（I）三-钯的有效钯催化的N-烷基取代的苯胺受阻芳族溴化物的有效胺化叔丁基膦溴化物二聚体[Pd（mu-Br）（t-Bu（3）P）]（2），一种新型的，可商购的且易于处理的催化剂。

  DOI：

  10.1021/jo020609d

文献信息

• Transition‐Metal‐Free Three‐Component Synthesis of Tertiary Aryl Amines from Nitro Compounds, Boronic Acids, and Trialkyl Phosphites
  作者：Silvia Roscales、Aurelio G. Csáky

  DOI：10.1002/adsc.201901009

  日期：2020.1.7

  aromatic amines is of continuous interest in chemistry. An exceptionally versatile three‐component reaction that directly transforms inexpensive nitro compounds, boronic acids, and trialkyl phosphites into tertiary aromatic amines has been realized. The reaction tolerates alkyl and aryl substituents on the nitro and boronic acid moieties, as well as functionalized phosphites. No transition‐metal catalysis

  芳族胺的合成在化学上一直受到关注。已经实现了一种极其通用的三组分反应，该反应可将廉价的硝基化合物，硼酸和亚磷酸三烷基酯直接转化为叔芳族胺。该反应容许硝基和硼酸部分上的烷基和芳基取代基以及官能化的亚磷酸酯。不需要过渡金属催化。该方法与其他经典的金属催化合成方法正交，因为它可以容忍卤素的存在，并且还可以合成功能化的化合物，例如α-氨基酯衍生物。
• USE OF SPIRO COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME
  申请人：LG Chem, Ltd.

  公开号：EP3357912B1

  公开（公告）日：2021-05-19
• Novel organic electroluminescent compounds and organic electroluminescent device using the same
  申请人：Kim Young Gil

  公开号：US20100108997A1

  公开（公告）日：2010-05-06

  Provided are novel organic electroluminescent compounds, and organic electroluminescent devices comprising the same as electroluminescent material. Specifically, the organic electroluminescent compounds according to the present invention are represented by Chemical Formula (1): wherein, at least one substituent(s) among Ar 1 , Ar 2 , R 6 , R 7 , R 8 , R 9 , R 10 , R 11 , R 12 , R 13 , R 14 and R 15 represent(s) The organic electroluminescent compounds according to the present invention exhibit high luminous efficiency and excellent life property of material, so that an OLED having very good operation life can be manufactured therefrom. Further, the organic electroluminescent compound according to the present invention, when it is contained in an electroluminescent layer or a hole transport layer, lowers the operation voltage to result in noticeable decrease in power consumption, with exhibiting at least comparable luminous efficiency as compared to conventional OLED's.
• ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES
  申请人：Universal Display Corporation

  公开号：US20190252623A1

  公开（公告）日：2019-08-15

  A compound of Formula I wherein Y is selected from the group consisting of NAr, O, S, and Se; Ar is an optionally substituted aryl or optionally substituted heteroaryl; and Z 1 to Z 8 are independently selected from C or N, wherein at least one of Z 2 or Z 3 is C, and at least one of Z 6 or Z 7 is C. R is selected from the group consisting of deuterium, alkyl, cycloalkyl, heteroalkyl, arylalkyl, alkoxy, aryloxy, amino, silyl, alkenyl, cycloalkenyl, heteroalkenyl, aryl, heteroaryl, nitrile, isonitrile, sulfanyl, and combinations thereof; or optionally R can join with Ar to from a ring; and with the provisios that R is not N-methyl-benzimidazole, and the compound is not compound A.
• ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME
  申请人：Samsung Display Co., Ltd.

  公开号：US20220102653A1

  公开（公告）日：2022-03-31

  An organometallic compound having a novel structure represented by Formula 1 and an organic light-emitting device including the same. In Formula 1, the substituents are the same as described in the Detailed Description.