N-(2,6-difluorobenzoyl)-N'-(2,3,4,5,6-pentafluorophenyl)urea

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-(2,6-difluorobenzoyl)-N'-(2,3,4,5,6-pentafluorophenyl)urea
• 英文别名: 2,6-difluoro-N-[(2,3,4,5,6-pentafluorophenyl)carbamoyl]benzamide
• 化学式: C₁₄H₅F₇N₂O₂
• 分子量: 366.195
• InChiKey: YNSCWPVKAAJXHV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.6
• 重原子数：
  25
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  58.2
• 氢给体数：
  2
• 氢受体数：
  9

反应信息

• 作为产物：
  描述：

  2,6-二氟苯甲酰氯 在 四氯化锡 作用下， 以 邻二甲苯 为溶剂， 反应 4.25h， 生成 N-(2,6-difluorobenzoyl)-N'-(2,3,4,5,6-pentafluorophenyl)urea
  参考文献：
  名称：

  New approach to the synthesis of 2,6-difluorobenzoyl isocyanate and its use in the preparation of N-(2,6-difluorobenzoyl)-N?-(polyfluoroaryl)ureas

  摘要：

  The treatment of 2,6-difluorobenzoyl chloride with trimethylsilyl isocyanate gave 2,6-difluorobenzoyl isocyanate. This product reacts with polyfluoroaromatic amines to give the corresponding N-(2,6-difluorobenzoyl)-N'-(polyfluoroaryl) urea, which hold potential as inhibitors for the biosynthesis of insect chitin.

  DOI：

  10.1007/bf00869540

文献信息

• ODINOKOV, V. N.;KUKOVINETS, O. S.;BIKULOVA, V. ZH.;LOZHKINA, E. A.;KOLESN+, 6-AYA BCEC. KONF. PO XIMII FTORORGAN. SOED., <NOVOSIBIRSK>, 26-28 IYUNYA,+
  作者：ODINOKOV, V. N.、KUKOVINETS, O. S.、BIKULOVA, V. ZH.、LOZHKINA, E. A.、KOLESN+

  DOI：——

  日期：——
• New approach to the synthesis of 2,6-difluorobenzoyl isocyanate and its use in the preparation of N-(2,6-difluorobenzoyl)-N?-(polyfluoroaryl)ureas
  作者：V. N. Odinokov、O. S. Kukovinets、E. A. Lozhkina、V. Zh. Bikulova、T. D. Petrova、I. V. Kolesnikova、V. E. Platonov、G. A. Tolstikov

  DOI：10.1007/bf00869540

  日期：1992.2

  The treatment of 2,6-difluorobenzoyl chloride with trimethylsilyl isocyanate gave 2,6-difluorobenzoyl isocyanate. This product reacts with polyfluoroaromatic amines to give the corresponding N-(2,6-difluorobenzoyl)-N'-(polyfluoroaryl) urea, which hold potential as inhibitors for the biosynthesis of insect chitin.