3-Allyl-tetrahydro-furan

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 氧唑烯
• 英文名称: 3-Allyl-tetrahydro-furan
• 英文别名: 3-Prop-2-enyloxolane
• 化学式: C₇H₁₂O
• 分子量: 112.172
• InChiKey: HZRCQMKFXBEMFJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.6
• 重原子数：
  8
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.71
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  3-溴丙烯 、 alkaline earth salt of/the/ methylsulfuric acid 在 乙醚 、 magnesium 作用下， 生成 3-Allyl-tetrahydro-furan 、 3-丁烯-1-醇
  参考文献：
  名称：

  Jur'ew et al., Zhurnal Obshchei Khimii, 1948, vol. 18, p. 1804,1806

  摘要：

  DOI：

文献信息

• Process for the preparation of 3-methyltetrahydrofuran
  申请人：EASTMAN CHEMICAL COMPANY

  公开号：EP1354881A1

  公开（公告）日：2003-10-22

  Disclosed is a process for the preparation of 3-methyltetrahydrofuran (MeTHF) from 3-(hydroxymethyl)tetrahydrofuran (HOMeTHF) by contacting HOMeTHF with hydrogen in the presence of an acidic, supported catalyst comprising a Group VIII metal.

  揭示了一种从3-(羟甲基)四氢呋喃（HOMeTHF）通过在酸性、载体催化剂的存在下将HOMeTHF与氢接触而制备3-甲基四氢呋喃（MeTHF）的方法，所述催化剂包括第VIII族金属。
• Process for the preparation of 11-oxaprostaglandins and intermediates therein
  申请人：——

  公开号：US20030166948A1

  公开（公告）日：2003-09-04

  For the preparation of an 11-oxaprostaglandin such as [2R,(1E,3R),3S,(4Z),4R)]-7-{tetrahydro-2-[4-(3-chlorophenoxy)-3-hydroxy-1-butenyl]-4-hydroxy-3-furanyl}-4-heptenoic acid and its ester derivatives, a novel process uses a novel enantiomerically enriched compound for formula (1) wherein the bond between carbon atoms y and z is either a single or double bond; R 1 is selected from vinyl, trialkylsilylethynyl, a formyl group protected as an acetal, or a protected hydroxymethyl group; R 2 is C 1-5 alkyl, optionally substituted at the terminus with an aryloxy or alkoxy group; and R 3 -R 6 are independently selected from C 1-6 alkyl and C 6-10 aryl. 1

  用于制备11-氧代前列腺素的新型方法，例如[2R，（1E，3R），3S，（4Z），4R）]-7-{四氢-2-[4-（3-氯苯氧）-3-羟基-1-丁烯基]-4-羟基-3-呋喃基}-4-庚烯酸及其酯衍生物，采用新型对映富集化合物的公式（1），其中碳原子y和z之间的键为单键或双键；R1选择自乙烯基，三烷基硅基乙炔基，作为缩醛保护的甲醛基，或保护的羟甲基基团；R2是C1-5烷基，可在末端用芳氧基或烷氧基取代；R3-R6分别选择自C1-6烷基和C6-10芳基。
• [EN] PROCESS FOR THE PREPARATION OF 11-OXAPROSTAGLANDINS AND INTERMEDIATES THEREIN<br/>[FR] PROCEDE DE PREPARATION DE 11-OXAPROSTAGLANDINES ET INTERMEDES
  申请人：CHIROTECH TECHNOLOGY LTD

  公开号：WO2001087897A1

  公开（公告）日：2001-11-22

  For the preparation of an 11-oxaprostaglandin such as [2R,(1E,3R),3S,(4Z),4R)]-7-tetrahydro-2-[4-(3-chlorophenoxy)-3-hydroxy-1-butenyl]-4-hydroxy-3-furanyl}-4-heptenoic acid and its ester derivatives, a novel process uses a novel enantiomerically enriched compound for formula (1) wherein the bond between carbon atoms y and z is either a single or double bond; R1 is selected from vinyl, trialkylsilylethynyl, a formyl group protected as an acetal, or a protected hydroxymethyl group; R2 is C¿1-5? alkyl, optionally substituted at the terminus with an aryloxy or alkoxy group; and R?3-R6¿ are independently selected from C¿1-6? alkyl and C6-10 aryl.

  为了制备类似于[2R，（1E，3R），3S，（4Z），4R）]-7-四氢-2-[4-（3-氯苯氧基）-3-羟基-1-丁烯基]-4-羟基-3-呋喃基}-4-庚烯酸及其酯衍生物的11-氧代前列腺素，采用了一种新型手段，使用了手性富集的化合物（1），其中碳原子y和z之间的键为单键或双键；R1从乙烯基，三烷基硅基乙炔基，以醚保护的甲酰基或保护的羟甲基基团中选择；R2是C1-5烷基，其末端可选地被芳氧基或烷氧基取代；R3-R6分别独立地选择自C1-6烷基和C6-10芳基。
• Thermoplastic elastomer blend, method of manufacture and use thereof
  申请人：Sunkara Babu Hari

  公开号：US20060247380A1

  公开（公告）日：2006-11-02

  A curable thermoplastic elastomeric composition comprising: (a) polytrimethylene ether ester elastomer; (b) crosslinkable poly(meth)acrylate rubber; and (c) a crosslinking system to crosslink the rubber. A melt processible thermoplastic elastomeric composition comprising: (a) a continuous phase comprising polytrimethylene ether ester elastomer; and (b) crosslinked poly(meth)acrylate rubber disperse phase. A process for manufacturing a melt processible thermoplastic elastomeric composition comprising the steps: (a) providing a cross-linkable poly(meth)acrylate rubber; (b) providing crosslinking system in an amount effective to crosslink the poly(meth)acrylate rubber; (c) providing polytrimethylene ether ester elastomer; (d) forming a mixture of the cross-linkable poly(meth)acrylate rubber, the polytrimethylene ether ester elastomer and the crosslinking system; (e) cross-linking the cross-linkable poly(meth)acrylate rubber in the mixture using the crosslinking system; and (f) recovering a melt processible thermoplastic elastomeric composition comprising the polyether ester elastomer as a continuous phase and the crosslinked poly(meth)acrylate rubber as a disperse phase. A shaped article (e.g., an extruded or molded article) made from a melt processible thermoplastic elastomeric composition comprising: (a) a continuous phase comprising polytrimethylene ether ester elastomer, and (b) a disperse phase comprising cross-linked poly(meth)acrylate rubber. Preferably the shaped article is selected from the group consisting of hoses, gaskets, films, belts, cable jackets, seals, gears and bearings.

  一种可治愈的热塑性弹性体组合物，包括：(a)聚三亚甲基醚酯弹性体；(b)可交联的聚(甲基)丙烯酸酯橡胶；和(c)交联系统，用于交联橡胶。一种可熔融加工的热塑性弹性体组合物，包括：(a)连续相包括聚三亚甲基醚酯酯弹性体；和(b)交联的聚(甲基)丙烯酸酯橡胶分散相。一种制造可熔融加工的热塑性弹性体组合物的方法，包括以下步骤：(a)提供可交联的聚(甲基)丙烯酸酯橡胶；(b)提供足够交联聚(甲基)丙烯酸酯橡胶的交联系统；(c)提供聚三亚甲基醚酯酯弹性体；(d)形成可交联聚(甲基)丙烯酸酯橡胶、聚三亚甲基醚酯酯弹性体和交联系统的混合物；(e)使用交联系统交联混合物中的可交联聚(甲基)丙烯酸酯橡胶；(f)回收包括聚醚酯弹性体作为连续相和交联聚(甲基)丙烯酸酯橡胶作为分散相的可熔融加工的热塑性弹性体组合物。由可熔融加工的热塑性弹性体组合物制成的成型品（例如挤出或模压的成型品），包括：(a)连续相包括聚三亚甲基醚酯酯弹性体；和(b)分散相包括交联的聚(甲基)丙烯酸酯橡胶。最好的成型品是从以下组合中选择的：软管、垫片、薄膜、皮带、电缆护套、密封件、齿轮和轴承。
• Process for preparing 2-alkyl-1,4-butanediols
  申请人：E.I. DU PONT DE NEMOURS AND COMPANY

  公开号：EP0133739A1

  公开（公告）日：1985-03-06

  2-Alkyl-1, 4-butanediols are prepared from 1, 4- butynediol or 1, 4-butenediol by catalytic hydrogenation and reaction with an aldehyde.

  2-烷基-1，4-丁二醇是由 1，4-丁炔二醇或 1，4-丁烯二醇通过催化加氢并与醛反应制备而成。