dinitrophenylmethanol

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: dinitrophenylmethanol
• 英文别名: Dinitrobenzyl alcohol；dinitro(phenyl)methanol
• 化学式: C₇H₆N₂O₅
• 分子量: 198.135
• InChiKey: IGTXUDQEBIVUOK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1
• 重原子数：
  14
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  112
• 氢给体数：
  1
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  邻苯二甲酸亚胺 、 dinitrophenylmethanol 、 偶氮二甲酸二乙酯 在 三苯基膦 作用下， 以 四氢呋喃 为溶剂， 以67%的产率得到2-(3,4-dinitrobenzyl)isoindole-1,3-dione
  参考文献：
  名称：

  Novel compounds and compositions for treating diseases asociated with protease activity

  摘要：

  描述了用于预防和治疗由肥大细胞介导的炎症性疾病的新化合物、组合物和方法。这些化合物、组合物和方法对预防和治疗与呼吸道相关的炎症性疾病（如哮喘和过敏性鼻炎）以及其他类型的免疫介导性炎症性疾病（如类风湿关节炎、结膜炎和炎症性肠病、各种皮肤病症以及某些病毒性疾病）有效。这些化合物包括对肥大细胞蛋白酶组胺酶的有效和选择性抑制剂。用于治疗这些疾病的组合物包括口服、吸入、局部和静脉制剂，以及包含这些制剂的装置。

  公开号：

  US20010053779A1

文献信息

• Compositions comprising a substituted benzimidazole useful for treating immunomediated inflammatory disorders
  申请人：Axys Pharmaceuticals, Inc.

  公开号：US20030212120A1

  公开（公告）日：2003-11-13

  Novel compounds, compositions and methods effective for the prevention and treatment of mast-cell mediated inflammatory disorders are described. The compounds, compositions and methods are effective for the prevention and treatment of inflammatory diseases associated with the respiratory tract, such as asthma and allergic rhinitis, as well as other types of immunomediated inflammatory disorders, such as rheumatoid arthritis, conjunctivitis and inflammatory bowel disease, various dermatological conditions, as well as certain viral conditions. The compounds comprise potent and selective inhibitors of the mast cell protease tryptase. The compositions for treating these conditions include oral, inhalant, topical and parenteral preparations as well as devices comprising such preparations.

  本发明描述了一种新型化合物、组合物和方法，用于预防和治疗由肥大细胞介导的炎症性疾病。这些化合物、组合物和方法对预防和治疗呼吸道相关的炎症性疾病，如哮喘和过敏性鼻炎，以及其他类型的免疫介导的炎症性疾病，如类风湿性关节炎、结膜炎和炎症性肠病、各种皮肤病和某些病毒性疾病均有效。这些化合物包括强效和选择性的肥大细胞蛋白酶酶抑制剂。治疗这些疾病的组合物包括口服、吸入、局部和静脉制剂，以及包含这些制剂的装置。
• Diamine, acid dianhydride, polymide composition having reactive group obtained therefrom, and processes for producing these
  申请人：——

  公开号：US20040158030A1

  公开（公告）日：2004-08-12

  The present invention relates to a novel diamine, a novel acid dianhydride, and a novel composition containing a polyimide produced from such diamine and acid dianhydride. Specifically, the present invention relates to an acid dianhydride that has a photosensitive group bonded through the mediation of an alkylene group or a fluoroalkylene group, a diamine that has a reactive group bonded through the mediation of an alkylene group or a fluoroalkylene group, and a polyimide composition that contains a novel polyimide having at least one of such acid dianhydride residue and diamine residue in a molecule thereof. Particularly, an object of the present invention is to provide a novel polyimide that has both photoreactivity and thermoreactivity specific to the reactive group and whose reactive group is selected from the group consisting of: organic groups derived from cinnamic acid, chalcone, furylacryloyl, benzalacetophenone, stilbene, coumarin, and pyrone; allyl; propargyl; ethinyl; CH 2 ═CH—; CH 2 ═C(CH 3 )—; and skeletons derived therefrom, and it to provide a novel diamine and a novel acid dianhydride that may be contained in the polyimide composition.

  本发明涉及一种新的二胺、一种新的酸二酐和一种含有由此类二胺和酸二酐制备的聚酰亚胺的新组合物。具体地，本发明涉及一种通过烷基或氟烷基介导的光敏基团键合的酸二酐，一种通过烷基或氟烷基介导的反应性基团键合的二胺，以及一种聚酰亚胺组合物，其分子中含有至少一个这样的酸二酐残基和二胺残基。特别地，本发明的目的是提供一种具有光反应性和热反应性的新型聚酰亚胺，其反应性基团来自以下群组：来自肉桂酸、查尔酮、呋喃丙烯酰、苯甲酰乙酮、亚苯基烯、香豆素和吡喃的有机基团；烯丙基；丙炔基；乙炔基；CH2═CH—；CH2═C(CH3)—；以及派生自这些基团的骨架，并提供可包含在聚酰亚胺组合物中的新型二胺和新型酸二酐。
• Method of producing liquid crystal aligning layer, liquid crystal aligning layer produced using the same, and liquid crystal display including liquid crystal aligning layer
  申请人：Kim Kyung-Jun

  公开号：US20070128378A1

  公开（公告）日：2007-06-07

  Disclosed is a method of producing a liquid crystal aligning layer, a liquid crystal aligning layer produced using the same, and a liquid crystal display including the liquid crystal aligning layer. In the liquid crystal aligning layer that is produced using the method, ultraviolet rays are radiated on movable chains of a polyamic acid polymer while the polyamic acid polymer is not imidized to perform alignment, and heat treatment is then performed to conduct imidization. Thus, thermal stability is excellent, residual images are not formed, and alignment of liquid crystals is excellent.

  本发明公开了一种制备液晶定向层的方法，使用该方法制备的液晶定向层以及包括该液晶定向层的液晶显示器。在使用该方法制备的液晶定向层中，当聚酰亚胺酸聚合物未进行亚酰亚胺化时，对聚酰亚胺酸聚合物的可移动链进行紫外线照射以进行定向，然后进行热处理以进行亚酰亚胺化。因此，热稳定性优异，不会形成残留图像，液晶的定向效果也很好。
• Radiation curable compositions
  申请人：Dow Corning Limited

  公开号：EP0542485A1

  公开（公告）日：1993-05-19

  Nitrobenzyl tosylate derivatives are very useful photo-curing catalysts to be used in radiation curable compositions comprising dialkenylethers or radiation curable organosiloxanes. Particularly useful are compositions comprising alkenylether functional siloxanes and nitrobenzyl tosylate derivatives. They may be used as coatings for cellulosic or other substrates.

  对甲苯磺酸盐硝基苄基衍生物是非常有用的光固化催化剂，可用于包含二烯醚或辐射固化有机硅氧烷的辐射固化组合物中。特别有用的是由烯醚官能团硅氧烷和硝基苄基甲苯磺酸盐衍生物组成的组合物。它们可用作纤维素或其他基材的涂层。
• Organosilicon compounds and compositions containing them
  申请人：Dow Corning Limited

  公开号：EP0542484A1

  公开（公告）日：1993-05-19

  Organosilicon compounds with a siloxane portion and groups of the general formula -OR′OCH=CHR˝ (i) linked via an Si-O-C bond, wherein R′ is a divalent hydrocarbon radical or a group -R°-(OR°)n⁻, wherein R° is alkylene and n is from 1 to 12, R˝ is H or alkyl are useful in radiation curable compositions, in which they are mixed with an initiator. The compositions are particularly useful in UV radiation curable relase coatings.

  具有硅氧烷部分和通式-OR′OCH=CHR˝(i)的基团通过 Si-O-C 键连接的有机硅化合物，其中 R′为二价烃基或基团-R°-(OR°)n-，其中 R°为亚烷基，n 为 1 至 12，R˝为 H 或烷基，可用于与引发剂混合的辐射固化组合物中。这些组合物尤其适用于紫外线辐射固化的涂料。