(7E,11E)-5-(benzylamino)-13-phenyltrideca-7,11-dien-1-ol

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (7E,11E)-5-(benzylamino)-13-phenyltrideca-7,11-dien-1-ol
• 化学式: C₂₆H₃₅NO
• 分子量: 377.57
• InChiKey: QUMXSDRUNCIVMG-ZUAGWBGVSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.9
• 重原子数：
  28
• 可旋转键数：
  14
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  32.3
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  tetrahydro-2H-2-pyranol 在 bis(acetylacetonate)nickel(II) 3-己炔 作用下， 以 四氢呋喃 为溶剂， 反应 4.0h， 生成 (7E,11E)-5-(benzylamino)-13-phenyltrideca-7,11-dien-1-ol
  参考文献：
  名称：

  Alkyne as a Spectator Ligand for the Nickel-Catalyzed Multicomponent Connection Reaction of Diphenylzinc, 1,3-Butadiene, Aldehydes, and Amines

  摘要：

  Under nickel catalysis, in the presence of 3-hexyne, the aldimines of aromatic amines react with Ph2Zn and one molecule of butadiene to provide 1 exclusively, while the aldimines of aliphatic amines react with Ph2Zn and two molecules of butadiene to provide 2 exclusively, where 3-hexyne serves as a spectator ligand controlling the selective formation of 1 and 2.

  DOI：

  10.1021/ol0703480

文献信息

• Alkyne as a Spectator Ligand for the Nickel-Catalyzed Multicomponent Connection Reaction of Diphenylzinc, 1,3-Butadiene, Aldehydes, and Amines
  作者：Masanari Kimura、Yasushi Tatsuyama、Keisuke Kojima、Yoshinao Tamaru

  DOI：10.1021/ol0703480

  日期：2007.5.1

  Under nickel catalysis, in the presence of 3-hexyne, the aldimines of aromatic amines react with Ph2Zn and one molecule of butadiene to provide 1 exclusively, while the aldimines of aliphatic amines react with Ph2Zn and two molecules of butadiene to provide 2 exclusively, where 3-hexyne serves as a spectator ligand controlling the selective formation of 1 and 2.