(4,6-dimethhyl-2-methoxy-phenyl)-(2,6-dimethyl-4-methoxy-phenyl)methane

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (4,6-dimethhyl-2-methoxy-phenyl)-(2,6-dimethyl-4-methoxy-phenyl)methane
• 英文别名: 1-Methoxy-2-[(4-methoxy-2,6-dimethylphenyl)methyl]-3,5-dimethylbenzene；1-methoxy-2-[(4-methoxy-2,6-dimethylphenyl)methyl]-3,5-dimethylbenzene
• 化学式: C₁₉H₂₄O₂
• 分子量: 284.398
• InChiKey: IHJOXPBXCLYSRQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.2
• 重原子数：
  21
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.37
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  三聚甲醛 、 3,5-二甲基苯甲醚 在 indium(III) chloride 作用下， 反应 6.0h， 以80%的产率得到bis-(4,6-dimethyl-2-methoxy-phenyl)methane
  参考文献：
  名称：

  An efficient synthesis of diarylmethanes via InCl3·4H2O-catalyzed dehydration of electron-rich arenes with trioxane

  摘要：

  A facile, efficient and environmentally benign procedure for the synthesis of diarylmethanes via the reaction of arenes with trioxane catalyzed by InCl3 center dot 4H(2)O was developed. The reactions of aromatic compounds bearing electron-donating group proceeded smoothly affording the corresponding diarylmethanes in good to excellent yields. (c) 2006 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2006.02.020

文献信息

• An efficient synthesis of diarylmethanes via InCl3·4H2O-catalyzed dehydration of electron-rich arenes with trioxane
  作者：Hong-Bin Sun、Ruimao Hua、Yingwu Yin

  DOI：10.1016/j.tetlet.2006.02.020

  日期：2006.4

  A facile, efficient and environmentally benign procedure for the synthesis of diarylmethanes via the reaction of arenes with trioxane catalyzed by InCl3 center dot 4H(2)O was developed. The reactions of aromatic compounds bearing electron-donating group proceeded smoothly affording the corresponding diarylmethanes in good to excellent yields. (c) 2006 Elsevier Ltd. All rights reserved.