4-(perfluoroethyl)-2-(trifluoromethyl)aniline

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-(perfluoroethyl)-2-(trifluoromethyl)aniline
• 英文别名: 2-trifluoromethyl-4-pentafluoroethylaniline；4-(1,1,2,2,2-pentafluoroethyl)-2-(trifluoromethyl)aniline
• 化学式: C₉H₅F₈N
• 分子量: 279.133
• InChiKey: ZGPBTJAQTAFJKR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.7
• 重原子数：
  18
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  26
• 氢给体数：
  1
• 氢受体数：
  9

反应信息

• 作为产物：
  描述：

  五氟碘乙烷 、 邻氨基三氟甲苯 在 sodium dithionite 、 碳酸氢钠 作用下， 以 水 、 N,N-二甲基甲酰胺 为溶剂， 反应 9.0h， 以21%的产率得到4-(perfluoroethyl)-2-(trifluoromethyl)aniline
  参考文献：
  名称：

  AMIDE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE AMIDE DERIVATIVE, AND USE OF THE PEST CONTROL AGENT

  摘要：

  公开号：

  EP2319830B1

文献信息

• PHTHALIC ACID DIAMIDE DERIVATIVES FLUORINE-CONTAINING ANILINE COMPOUNDS AS STARTING MATERIAL, AGRICULTURAL AND HORTICULTURAL INSECTICIDES, AND A METHOD FOR APPLICATION OF THE INSECTICIDES
  申请人：——

  公开号：US20010041814A1

  公开（公告）日：2001-11-15

  The present invention provides a phthalic acid diamide derivative represented by the general formula (I) 1 (wherein R 1 , R 2 and R 3 are each H, C 3 -C 6 cycloalkyl group, group of the formula —A 1 —Q l or the like; X may be the same or different and are each halogen atom, nitro group, phenyl group, group of the formula —A 2 —R 7 or the like; n is 1 to 4; Y may be same or different and are each halogen atom, cyano group, phenyl group, group of the formula —A 2 —R 7 or the like; m is 1 to 5; Z 1 and Z 2 are each O or S), fluorine-containing aniline compound represented by the general formula (ST-I) as starting material for said phthalic acid diamide derivative 2 (wherein R a is halogen atom, C 1 -C 6 alkyl group or the like and R b , R c and R d is H or C 2 -C 6 perfluoroalkyl group), and an agricultural and horticultural insecticide containing said phthaldiamide derivative, as well as to provide a method for use of said insecticide. The agricultural and horticultural insecticides of the present invention show excellent activities for controlling injurious insects.

  本发明提供了一种邻苯二甲酰胺衍生物，其由通式（I）1表示（其中R1、R2和R3分别为H、C3-C6环烷基、—A1—Ql或类似基团；X可以相同也可以不同，分别为卤素原子、硝基、苯基、—A2—R7或类似基团；n为1至4；Y可以相同也可以不同，分别为卤素原子、氰基、苯基、—A2—R7或类似基团；m为1至5；Z1和Z2分别为O或S），以通式（ST-I）表示的含氟苯胺化合物作为所述邻苯二甲酰胺衍生物的起始原料2（其中Ra为卤素原子、C1-C6烷基或类似基团，而Rb、Rc和Rd为H或C2-C6全氟烷基），以及含有所述邻苯二甲酰胺衍生物的农业和园艺杀虫剂，同时提供了使用该杀虫剂的方法。本发明的农业和园艺杀虫剂对控制有害昆虫表现出优异的活性。
• Phthalic acid diamide derivatives, fluorine-containing aniline compounds as starting material, agricultural and horticultural insecticides, and a method for application of the insecticides
  申请人：——

  公开号：US20030055287A1

  公开（公告）日：2003-03-20

  The present invention provides a phthalic acid diamide derivative represented by the general formula (I) 1 (wherein R 1 , R 2 and R 3 are each H, C 3 -C 6 cycloalkyl group, group of the formula -A 1 -Q l or the like; X may be the same or different and are each halogen atom, nitro group, phenyl group, group of the formula -A 2 -R 7 or the like; n is 1 to 4; Y may be same or different and are each halogen atom, cyano group, phenyl group, group of the formula -A 2 -R 7 or the like; m is 1 to 5; Z 1 and Z 2 are each O or S), fluorine-containing aniline compound represented by the general formula (ST-I) as starting material for said phthalic acid diamide derivative 2 (wherein R a is halogen atom, C 1 -C 6 alkyl group or the like and R b , R c and R d is H or C 2 -C 6 perfluoroalkyl group), and an agricultural and horticultural insecticide containing said phthaldiamide derivative, as well as to provide a method for use of said insecticide. The agricultural and horticultural insecticides of the present invention show excellent activities for controlling injurious insects.

  本发明提供了一种邻苯二甲酰胺衍生物，其表示为通式（I）1（其中R1、R2和R3分别为H、C3-C6环烷基、-A1-Ql或类似基团；X可以相同或不同，分别为卤素原子、硝基、苯基、-A2-R7或类似基团；n为1至4；Y可以相同或不同，分别为卤素原子、氰基、苯基、-A2-R7或类似基团；m为1至5；Z1和Z2分别为O或S），以及以含氟苯胺化合物为起始物质的邻苯二甲酰胺衍生物2（其中Ra为卤素原子、C1-C6烷基或类似基团，而Rb、Rc和Rd为H或C2-C6全氟烷基），以及包含所述邻苯二甲酰胺衍生物的农业和园艺杀虫剂，同时提供了使用所述杀虫剂的方法。本发明的农业和园艺杀虫剂表现出优异的控制有害昆虫的活性。
• AMIDE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE AMIDE DERIVATIVE, AND USE OF THE AMIDE DERIVATIVE
  申请人：Kobayashi Yumi

  公开号：US20110201687A1

  公开（公告）日：2011-08-18

  An amide derivative represented by the following Formula (1) is provided as an amide derivative showing a significantly excellent effect for a pest control action. In the following Formula (1), A represents a carbon atom, a nitrogen atom, or the like, and K represents a non-metal atomic group necessary for forming a cyclic linking group derived from benzene or a heterocyclie. X represents a halogen atom or the like; n represents an integer of from 0 to 4 . R 1 and R 2 represent hydrogen atoms, alkyl groups, or the like. T represents —C(=G 1 )-Q 1 or —C(=G 1 )-G 2 Q 2 , and G 1 to G 3 each represent oxygen atoms or the like. Q 1 and Q 2 each represent a hydrogen atom, an alkyl group, an aryl group, or the like. Y 1 and Y 5 each represent a halogen atom or the like, Y 2 and Y 4 each represent a hydrogen atom or the like, and Y 3 represents a C2-C5 haloalkyl group.

  提供以下式子（1）表示的酰胺衍生物，作为一种表现出显著杀虫作用的酰胺衍生物。在下面的式子（1）中，A代表碳原子、氮原子或类似物，K代表必要的非金属原子团，用于形成从苯或杂环中得到的环链连接基。X代表卤素原子或类似物；n代表0至4的整数。R1和R2代表氢原子、烷基或类似物。T代表- C（= G1）- Q1或- C（= G1）- G2Q2，G1到G3每个代表氧原子或类似物。Q1和Q2每个代表氢原子、烷基、芳基或类似物。Y1和Y5每个代表卤素原子或类似物，Y2和Y4每个代表氢原子或类似物，Y3代表C2-C5卤代烷基。
• Amide derivative, pest control agent containing the amide derivative, and use of the amide derivative
  申请人：Kobayashi Yumi

  公开号：US08686044B2

  公开（公告）日：2014-04-01

  An amide derivative represented by the following Formula (1) is provided as an amide derivative showing a significantly excellent effect for a pest control action. In the following Formula (1), A represents a carbon atom, a nitrogen atom, or the like, and K represents a non-metal atomic group necessary for forming a cyclic linking group derived from benzene or a heterocyclie. X represents a halogen atom or the like; n represents an integer of from 0 to 4. R1 and R2 represent hydrogen atoms, alkyl groups, or the like. T represents —C(=G1)-Q1 or —C(=G1)-G2Q2, and G1 to G3 each represent oxygen atoms or the like. Q1 and Q2 each represent a hydrogen atom, an alkyl group, an aryl group, or the like. Y1 and Y5 each represent a halogen atom or the like, Y2 and Y4 each represent a hydrogen atom or the like, and Y3 represents a C2-C5 haloalkyl group.

  提供了一种由以下公式（1）表示的酰胺衍生物，作为显示显著卓越的杀虫作用的酰胺衍生物。在下述公式（1）中，A代表碳原子、氮原子或类似物，K代表必要的非金属原子团，以形成从苯或杂环中导出的环状连接基。X代表卤素原子或类似物；n代表0到4的整数。R1和R2代表氢原子、烷基或类似物。T代表-C（=G1）-Q1或-C（=G1）-G2Q2，G1至G3各自代表氧原子或类似物。Q1和Q2各自代表氢原子、烷基、芳基或类似物。Y1和Y5各自代表卤素原子或类似物，Y2和Y4各自代表氢原子或类似物，Y3代表C2-C5卤代烷基。
• Fluorine-containing aniline compounds
  申请人：NIHON NOHYAKU CO., LTD.

  公开号：EP0936212A1

  公开（公告）日：1999-08-18

  The present invention provides a novel fluorine-containing aniline compound represented by the general formula (I): (wherein R1 is a halogen atom, a C1-C6 alkyl group, a C1-C6 alkoxy group or a trifluoromethyl group, and each of R2, R3 and R4 is H or a C2-C6 perfluoroalkyl group, provided that at least one of R2, R3 and R4 is not H; that R3 is neither a pentafluoroethyl group nor a n-heptafluoropropyl group, when R1 is F and each of R2 and R4 is H; and that R3 is not a pentafluoroethyl group, when R1 is a methyl group and each of R2 and R4 is H), which is useful as an intermediate of a medicine, agrochemical, chemical product, etc.

  本发明提供了通式(I)代表的新型含氟苯胺化合物： (其中 R1 是卤原子、C1-C6 烷基、C1-C6 烷氧基或三氟甲基，R2、R3 和 R4 各为 H 或 C2-C6 全氟烷基，条件是 R2、R3 和 R4 中至少有一个不是 H；当 R1 为 F 且 R2 和 R4 中的每一个均为 H 时，R3 既不是五氟乙基，也不是正七氟丙基；当 R1 为甲基且 R2 和 R4 中的每一个均为 H 时，R3 不是五氟乙基），可用作药物、农用化学品、化工产品等的中间体。