N-(6-hydroxyhexyl)-4-picolinium bromide

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: N-(6-hydroxyhexyl)-4-picolinium bromide
• 英文别名: N-(6-hydoxyhexyl)-4-picolinium bromide；6-(4-methylpyridin-1-ium-1-yl)hexan-1-ol;bromide
• 化学式: Br*C₁₂H₂₀NO
• 分子量: 274.201
• InChiKey: DGGXXZFDIRDBPB-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  -1.16
• 重原子数：
  15
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.58
• 拓扑面积：
  24.1
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  N-(6-hydroxyhexyl)-4-picolinium bromide 在 哌啶 、 吡啶 、 silver nitrate 作用下， 以 四氢呋喃 、 乙醇 为溶剂， 反应 7.0h， 生成
  参考文献：
  名称：

  一种有机小分子荧光染料及其制备方法和用途

  摘要：

  本发明提供了一种有机小分子荧光染料及其制备方法和用途，所示荧光染料具有如下式I表示的结构，或其药学上可接受的盐，或其对映异构体、非对映异构体、互变异构体或溶剂化物。本发明的荧光染料应用于寡核苷酸修饰时，由于本发明的有机小分子染料具有90至200nm斯托克斯位移，从而解决了测量中因串扰以及后向散射效应带来的自淬灭和测量误差的问题，同时使生物偶联方法更有效。

  公开号：

  CN114958025A
• 作为产物：
  描述：

  4-甲基吡啶 、 6-溴正己醇 在 乙醚 作用下， 以 乙醇 为溶剂， 反应 36.0h， 以The product was obtained as an orange-yellow viscous liquid in a 100% yield的产率得到N-(6-hydroxyhexyl)-4-picolinium bromide
  参考文献：
  名称：

  Zwitterionic chromophores and polymers containing such chromophores

  摘要：

  通过将具有所需功能基团（优选为-OH）的吡啶卤化物与锂TCNQ加合物反应，可以获得非线性色团。如果需要，可以将色团嫁接聚合到具有互补功能基团（优选为羧基）的聚合物上。可选地，聚合物可以进行交联。这种聚合物可用于电光器件。

  公开号：

  US06894169B1

文献信息

• Metathesis syntheses of pheromones or their components
  申请人：——

  公开号：US20020022741A1

  公开（公告）日：2002-02-21

  The present invention relates to metathesis syntheses for insect sex-attractant pheromones or their components, such as E-5-decenyl acetate, the major component of the Peach Twig Borer pheromone; (5R, 6S)-6-acetoxy-5-hexadecanolide, the mosquito oviposition attractant pheromone; E9, Z11-hexadecadienal, the pecan nut casebearer moth pheromone; 9-tetradecenyl formate, an analog of the Diamondback Moth (DBM) pheromone; 11-tetradecenyl acetate, the Omnivorous Leafroller (OLR) pheromone; E-4-tridecenyl acetate, the major component of the Tomato Pinworm (TPW) pheromone; E,E-8,10-dodecadienol, the Codling Moth (CM) pheromone. The syntheses preferably employ a Class I-IV metathesis catalyst, entail few reaction steps, use generally commercially available starting materials, and have relatively short process times. These syntheses produce good yields without the need for expensive or sophisticated equipment. The invention also provides an inexpensive route for producing omega-haloalkenols by cross-metathesizing alpha-omega-diacetoxy alkenes and alpha-omega-dihalides to yield omega-haloalkenols, which are easily converted into omega-haloalkanols under traditional hydrogenation methods.

  本发明涉及对昆虫性诱素或其组分进行交换合成，如E-5-癸烯醇醋酸酯，桃枝蠕蛾性信息素的主要成分；（5R, 6S）-6-乙酰氧基-5-十六醇内酯，蚊子产卵引诱素；E9, Z11-癸二烯醛，山核桃果蛾性信息素；9-十四烯酸甲酯，菜青虫性信息素的类似物；11-十四烯醇醋酸酯，杂食卷叶蛾性信息素；E-4-十三烯醇醋酸酯，番茄针孔螟性信息素的主要成分；E,E-8,10-十二二烯醇，苹果蛾性信息素。这些合成通常采用I-IV类交换催化剂，步骤较少，使用通常易得的起始物质，并具有相对较短的工艺时间。这些合成产量良好，无需昂贵或复杂的设备。该发明还提供了通过交叉交换α-Ω-二乙酰基烯烃和α-Ω-二卤代烃来产生Ω-卤代烯醇的廉价途径，后者可以在传统的氢化方法下轻松转化为Ω-卤代烷醇。
• METATHESIS SYNTHESES OF PHEROMONES OR THEIR COMPONENTS
  申请人：Pederson, Richard L.

  公开号：EP1230207B1

  公开（公告）日：2005-06-22
• US6696597B2
  申请人：——

  公开号：US6696597B2

  公开（公告）日：2004-02-24
• US6894169B1
  申请人：——

  公开号：US6894169B1

  公开（公告）日：2005-05-17
• [EN] METATHESIS SYNTHESES OF PHEROMONES OR THEIR COMPONENTS<br/>[FR] SYNTHESE DE PHEROMONES OU DE LEURS COMPOSANTS PAR METATHESE
  申请人：PEDERSON RICHARD L

  公开号：WO2001036368A2

  公开（公告）日：2001-05-25

  The present invention relates to metathesis syntheses for insect sex-attractant pheromones or their components, such as E-5-decenyl acetate, the major component of the Peach Twig Borer pheromone; (5R, 6S)-6-acetoxy-5-hexadecanolide, the mosquito oviposition attractant pheromone; E9, Z11-hexadecadienal, the pecan nut casebearer moth pheromone; 9-tetradecenyl formate, an analog of the Diamondback Moth (DBM) pheromone; 11-tetradecenyl acetate, the Omnivorous Leafroller (OLR) pheromone; E-4-tridecenyl acetate, the major component of the Tomato Pinworm (TPW) pheromone; E,E-8,10-dodecadienol, the Codling Moth (CM) pheromone. The syntheses preferably employ a Class I-IV metathesis catalyst, entail few reaction steps, use generally commercially available starting materials, and have relatively short process times. These syntheses produce good yields without the need for expensive or sophisticated equipment. The invention also provides an inexpensive route for producing omega-haloalkenols by cross-metathesizing alpha-omega-diacetoxy alkenes and alpha-omega-dihalides to yield omega-haloalkenols, which are easily converted into omega-haloalkanols under traditional hydrogenation methods.