2-benzyl-5-methyl-thiazol-4-one

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-benzyl-5-methyl-thiazol-4-one
• 英文别名: 2-Benzyl-5-methyl-thiazol-4-on；2-Benzyl-5-methyl-1,3-thiazol-4-one
• 化学式: C₁₁H₁₁NOS
• 分子量: 205.28
• InChiKey: VVBDEQLMPIXZJU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  14
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.27
• 拓扑面积：
  54.7
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  2-溴丙酸 、 2-苯基硫代乙酰胺 生成 2-benzyl-5-methyl-thiazol-4-one
  参考文献：
  名称：

  Chabrier et al., Bulletin de la Societe Chimique de France, 1949, p. 237,240

  摘要：

  DOI：

文献信息

• Novel enzymes which dehydrate glycerol
  申请人：Genencor International, Inc.

  公开号：EP1944363A1

  公开（公告）日：2008-07-16

  The present invention relates to improved methods and reagents for the production of 1,3-propanediol. In particular, the present invention provides novel thermophilic organisms and thermostable enzymes capable of catalyzing the fermentation of glycerol to 1,3-propanediol. The present invention also relates to methods of isolating such thermophilic organisms, methods of cloning polynucleotides that encode such enzymes, polynucleotides encoding such enzymes, and methods of using such enzymes and organisms for the production of 1,3-propanediol.

  本发明涉及生产 1,3-丙二醇的改进方法和试剂。特别是，本发明提供了能够催化甘油发酵成 1,3-丙二醇的新型嗜热生物和恒温酶。本发明还涉及分离这种嗜热生物的方法、克隆编码这种酶的多核苷酸的方法、编码这种酶的多核苷酸以及使用这种酶和生物生产1,3-丙二醇的方法。
• NOVEL ENZYMES WHICH DEHYDRATE GLYCEROL
  申请人：GENENCOR INTERNATIONAL, INC.

  公开号：EP1218530A2

  公开（公告）日：2002-07-03
• US6803218B1
  申请人：——

  公开号：US6803218B1

  公开（公告）日：2004-10-12
• [EN] NOVEL ENZYMES WHICH DEHYDRATE GLYCEROL<br/>[FR] NOUVEAUX ENZYMES QUI DESHYDRATENT LE GLYCEROL
  申请人：GENENCOR INT

  公开号：WO2001021825A2

  公开（公告）日：2001-03-29

  The present invention relates to improved methods and reagents for the production of 1,3-propanediol. In particular, the present invention provides novel thermophilic organisms and thermostable enzymes capable of catalyzing the fermentation of glycerol to 1,3-propanediol. The present invention also relates to methods of isolating such thermophilic organisms, methods of cloning polynucleotides that encode such enzymes, polynucleotides encoding such enzymes, and methods of using such enzymes and organisms for the production of 1,3-propanediol.