2-(3-cyclohexenyl)-4-methoxymethyl-1,3-dioxolane

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二氧戊环
• 英文名称: 2-(3-cyclohexenyl)-4-methoxymethyl-1,3-dioxolane
• 英文别名: 2-Cyclohex-3-en-1-yl-4-(methoxymethyl)-1,3-dioxolane
• 化学式: C₁₁H₁₈O₃
• 分子量: 198.262
• InChiKey: YWZMPBHTCYFRJF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.6
• 重原子数：
  14
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.82
• 拓扑面积：
  27.7
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  3-环己烯甲醛 在 sodium hydroxide 、 KU-2 cation exchanger 作用下， 以 甲苯 为溶剂， 反应 5.0h， 生成 2-(3-cyclohexenyl)-4-methoxymethyl-1,3-dioxolane
  参考文献：
  名称：

  摘要：

  Reactions of 3-cyclohexenecarbaldehyde, 6-methyl-3-cyclohexenecarbaldehyde, bicyclo[2.2.1]-hept-5-ene-endo-2-carbaldehyde, and benzaldehyde with 1,2-propanediol and 3-chloro-1,2-propanediol gave the corresponding 2,4-substituted 1,3-dioxolanes. Their reactions with peroxyacetic acid, bromine, dichlorocarbene, and nucleophiles were studied. The effect of the substituents in the diol and aldehyde on their relative reactivity is discussed.

  DOI：

  10.1023/a:1012350122851

文献信息

• ——
  作者：A. Kh. Kerimov

  DOI：10.1023/a:1012350122851

  日期：——

  Reactions of 3-cyclohexenecarbaldehyde, 6-methyl-3-cyclohexenecarbaldehyde, bicyclo[2.2.1]-hept-5-ene-endo-2-carbaldehyde, and benzaldehyde with 1,2-propanediol and 3-chloro-1,2-propanediol gave the corresponding 2,4-substituted 1,3-dioxolanes. Their reactions with peroxyacetic acid, bromine, dichlorocarbene, and nucleophiles were studied. The effect of the substituents in the diol and aldehyde on their relative reactivity is discussed.