3-(benzenetellurenyl)propanesulfonic acid sodium salt

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 3-(benzenetellurenyl)propanesulfonic acid sodium salt
• 英文别名: Sodium;3-phenyltellanylpropane-1-sulfonate
• 化学式: C₉H₁₁O₃STe*Na
• 分子量: 349.84
• InChiKey: VIWNBRXDRFZKOE-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  -2.63
• 重原子数：
  15
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  65.6
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  cobalt(II) tetrafluoroborate hexahydrate 、 二甲基乙二醛肟 、 3-(benzenetellurenyl)propanesulfonic acid sodium salt 在 碳酸氢钠 作用下， 以 水 为溶剂， 反应 0.5h， 生成 [Co(dimethylglyoximate)₂{PhTe(CH₂)₃SO₃Na}₂]BF₄*2H₂O 、 [Co(dimethylglyoximate)₂{PhTe(CH₂)₃SO₃Na}₂]BF₄*2H₂O
  参考文献：
  名称：

  Coordination of diorganotellurides to cobalt(III) in cobaloximes

  摘要：

  The unexpectedly aqueous stable bis-tellurium cationic complex [Co(dmgH)(2)(PhTe(CH2)(3)SO3Na)2](+)(1(+)) (dmgH(-) = dimethylglyoximate) has been fully characterized in the solid state and in solution. The UV-Vis spectrum of 1(+) differs from that of earlier cobaloximes, exhibiting a new low energy band centered at lambda(max) =425 nm (epsilon similar to 26155 dm(3) mol(-1) cm(-1)) and assigned with DFT calculations to allowed LMCT transitions. H-1, C-13, and Te-125 NMR spectra show unequivocally that two diastereomers exist equally in water, 50% of the achiral C-2h, meso-[Co(dmgH)(2)(R,S-PhTe(CH2)(3)SO3Na)(2)](+) and 50% of the chiral C-2 rac-[Co(dmgH)(2)(PhTe(CH2)(3)SO3Na)(2)](+) (25% of each enantiomer [Co(dmgH)(2)(R,R-PhTe(CH2)(3)SO3Na)(2)](+) and [Co(dmgH)(2)(S,S-PhTe(CH2)(3)SO3Na)(2)](+)). The solid-state structure of the meso diastereomer has been solved. Neutral mono-tellurium complexes [CoCl(dmgH)(2)[Te(p-MeO-C6H4)(2))](2) and [CoCl(dpgH)(2) (Te(p-MeO-C6H4)(2))](3) (dpgH(-) = diphenylglyoximate) have also been characterized in the solid (3) state and in solution (2 and 3). The structural results provide the first examples of Co(III)-Te bonds. The solid-state structure of the related cobaloxime salt [Co(dmgH)(2)(py)(2)][CoCl2(dmgH)(2)] obtained during one synthesis is also reported. (C) 2012 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.poly.2012.08.017
• 作为产物：
  描述：

  1,3-丙烷磺内酯 、 联苯二碲 在 sodium tetrahydroborate 作用下， 以 乙醇 为溶剂， 反应 1.0h， 以94%的产率得到3-(benzenetellurenyl)propanesulfonic acid sodium salt
  参考文献：
  名称：

  具有硫醇过氧化物酶和抗氧化活性的新型水溶性二有机基碲化物。

  摘要：

  制备了具有磺丙基的新型水溶性二芳基碲化物，烷基芳基碲化物和二烷基碲化物，发现它们具有有效的过氧化物分解和断链抗氧化能力。将双（4-羟苯基）碲化物（4）的二锂，二钠，二钾和双-四甲基铵盐在叔丁醇水溶液中用2.3当量的1,3-丙磺酸内酯处理，得到相应的双-O盐5 -磺丙基丙基二芳基碲化物。用硼氢化钠在乙醇中还原各种二芳基二碲化物。将丙磺酸内酯加到所得的硬脂酸神经酸钠中后，沉淀出相应的3-芳基碲基丙烯基丙烷磺酸钠盐8。二苯基二硒化物和二丁基二碲化物类似地反应，分别得到3-苯硒烯基丙烷磺酸（9）和4-碲辛烷磺酸（10）的钠盐。使用耦合的GSSG还原酶测定法在pH = 7.4时评估了水溶性化合物的谷胱甘肽过氧化物酶样活性。事实证明，二烷基碲化物10是最有效的催化剂。在该模型中，几种烷基芳基碲化物8也比任何先前测试过的有机碲化合物更有效。庞大的和吸电子的芳基取代基似乎降低了活性，而给电子基团则增强了活

  DOI：

  10.1021/jo990842k

文献信息

• Novel Water-Soluble Diorganyl Tellurides with Thiol Peroxidase and Antioxidant Activity
  作者：Takahiro Kanda、Lars Engman、Ian A. Cotgreave、Garth Powis

  DOI：10.1021/jo990842k

  日期：1999.10.1

  at pH = 7.4 by using the coupled GSSG reductase assay. Dialkyl telluride 10 turned out to be the most efficient catalyst. Several alkyl aryl tellurides 8 were also more efficient than any of the previously tested organotellurium compounds in this model. Bulky and electron-withdrawing aryl substituents seemed to reduce activity, whereas electron-donating groups enhanced it. Alkyl aryl selenide 9 was

  制备了具有磺丙基的新型水溶性二芳基碲化物，烷基芳基碲化物和二烷基碲化物，发现它们具有有效的过氧化物分解和断链抗氧化能力。将双（4-羟苯基）碲化物（4）的二锂，二钠，二钾和双-四甲基铵盐在叔丁醇水溶液中用2.3当量的1,3-丙磺酸内酯处理，得到相应的双-O盐5 -磺丙基丙基二芳基碲化物。用硼氢化钠在乙醇中还原各种二芳基二碲化物。将丙磺酸内酯加到所得的硬脂酸神经酸钠中后，沉淀出相应的3-芳基碲基丙烯基丙烷磺酸钠盐8。二苯基二硒化物和二丁基二碲化物类似地反应，分别得到3-苯硒烯基丙烷磺酸（9）和4-碲辛烷磺酸（10）的钠盐。使用耦合的GSSG还原酶测定法在pH = 7.4时评估了水溶性化合物的谷胱甘肽过氧化物酶样活性。事实证明，二烷基碲化物10是最有效的催化剂。在该模型中，几种烷基芳基碲化物8也比任何先前测试过的有机碲化合物更有效。庞大的和吸电子的芳基取代基似乎降低了活性，而给电子基团则增强了活
• Coordination of diorganotellurides to cobalt(III) in cobaloximes
  作者：Gabriel García-Herbosa、William R. McNamara、William W. Brennessel、José V. Cuevas、Sandip Sur、Richard Eisenberg

  DOI：10.1016/j.poly.2012.08.017

  日期：2013.7

  The unexpectedly aqueous stable bis-tellurium cationic complex [Co(dmgH)(2)(PhTe(CH2)(3)SO3Na)2](+)(1(+)) (dmgH(-) = dimethylglyoximate) has been fully characterized in the solid state and in solution. The UV-Vis spectrum of 1(+) differs from that of earlier cobaloximes, exhibiting a new low energy band centered at lambda(max) =425 nm (epsilon similar to 26155 dm(3) mol(-1) cm(-1)) and assigned with DFT calculations to allowed LMCT transitions. H-1, C-13, and Te-125 NMR spectra show unequivocally that two diastereomers exist equally in water, 50% of the achiral C-2h, meso-[Co(dmgH)(2)(R,S-PhTe(CH2)(3)SO3Na)(2)](+) and 50% of the chiral C-2 rac-[Co(dmgH)(2)(PhTe(CH2)(3)SO3Na)(2)](+) (25% of each enantiomer [Co(dmgH)(2)(R,R-PhTe(CH2)(3)SO3Na)(2)](+) and [Co(dmgH)(2)(S,S-PhTe(CH2)(3)SO3Na)(2)](+)). The solid-state structure of the meso diastereomer has been solved. Neutral mono-tellurium complexes [CoCl(dmgH)(2)[Te(p-MeO-C6H4)(2))](2) and [CoCl(dpgH)(2) (Te(p-MeO-C6H4)(2))](3) (dpgH(-) = diphenylglyoximate) have also been characterized in the solid (3) state and in solution (2 and 3). The structural results provide the first examples of Co(III)-Te bonds. The solid-state structure of the related cobaloxime salt [Co(dmgH)(2)(py)(2)][CoCl2(dmgH)(2)] obtained during one synthesis is also reported. (C) 2012 Elsevier Ltd. All rights reserved.