(2E)-N-benzylhept-2-en-1-amine

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (2E)-N-benzylhept-2-en-1-amine
• 英文别名: benzylhept-2-enylamine；N-benzyl-N-(2-heptenyl)amine；(E)-N-benzylhept-2-en-1-amine
• 化学式: C₁₄H₂₁N
• 分子量: 203.327
• InChiKey: UQNZKKSKGNBDHZ-WEVVVXLNSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.7
• 重原子数：
  15
• 可旋转键数：
  7
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.43
• 拓扑面积：
  12
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  (2e)-N-benzyl-3-chloroprop-2-en-1-amine 、 正丁基氯化镁 在 iron(III)-acetylacetonate 作用下， 以 四氢呋喃 、 N-甲基吡咯烷酮 为溶剂， 反应 1.5h， 以89%的产率得到(2E)-N-benzylhept-2-en-1-amine
  参考文献：
  名称：

  Stereoselective synthesis of allylamines by iron-catalyzed cross-coupling of 3-chloroprop-2-en-1-amines with grignard reagents. Synthesis of naftifine

  摘要：

  A general procedure for the synthesis of trans- and cis-allylamines has been developed on the basis of iron-catalyzed cross-coupling of Grignard reagents with stereochemically pure 3-chloroprop-2-en-1-amines prepared by allylation of amines with commercially available 1,3-dichloropropene isomers.

  DOI：

  10.1134/s1070428014030038

文献信息

• Synthesis of Allylamines fromAlkynes and Iminium Ions
  作者：Herbert Mayr、Susanne Rehn、Armin R. Ofial

  DOI：10.1055/s-2003-41028

  日期：——

  The iminium salt Bn2N+=CH2 SnCl5 - undergoesene reactions with inverse electron demand with alkynes and withthe triple bond of enynes to give benzylideneammonium ions in aprotic solvents.Their hydrolysis yields N-benzylallylaminesin good yields. Mannich reaction products, which are the main productsunder more nucleophilic reaction conditions, have not been detected.

  亚胺盐 Bn2N+=CH2 SnCl5 - 在非质子溶剂中与炔烃及烯炔的三键进行反电子需求的ene反应，生成苄叉基铵离子。其水解产物为N-苄基烯丙胺，产率良好。在更具亲核性的反应条件下，曼尼希反应产物（主要产物）尚未被检测到。
• 1-(3-substituted benzyl)-3-halogeno-4-(1-halogeno-alkyl)-2-pyrrolidinone
  申请人：Mitsui Toatsu Chemicals, Inc.

  公开号：US05114466A1

  公开（公告）日：1992-05-19

  1-(3-Substituted benzyl)-3-halogeno-4-(1-halogenoalkyl)-2-pyrrolidinones of the general formula (I): ##STR1## where X represents a hydrogen atom or halogen atom, Y and Z each represents a chlorine atom or bromine atom, and R represents an alkyl group with 2 to 4 carbon atoms, are herbicides useful in rice paddy fields to control weeds therein, especially Echinochloa crusgalli and can be produced subjecting the corresponding 3-dihalogeno compounds to dehalogenation to remove one of the halogen atoms or by cyclizing a 2,2-dihalogenoacetamide derivative represented by the general formula (II) under the presence of an appropriate catalyst; ##STR2## in which X, Y, Z and R respectively have the same meanings as described above.

  通式（I）中，1-(3-取代苯基)-3-卤代-4-(1-卤代烷基)-2-吡咯酮，其中X代表氢原子或卤素原子，Y和Z分别代表氯原子或溴原子，R代表2至4个碳原子的烷基。这些除草剂可用于水稻田中控制杂草，尤其是谷子草，可通过将相应的3-二卤代化合物脱卤素去除其中的一个卤素原子或在适当催化剂的存在下将通式（II）所表示的2,2-二卤代乙酰胺衍生物环化而制得；其中X、Y、Z和R分别具有上述相同的含义。
• 1-(3-substituted benzyl)-3-halogeno-4-(1-halogenoalkyl)-2-pyrrolidinone derivatives and herbicides containing them
  申请人：MITSUI TOATSU CHEMICALS, Inc.

  公开号：EP0402893A1

  公开（公告）日：1990-12-19

  1-(3-Substituted benzyl)-3-halogeno-4-(1-halogenoalkyl)-2-pyrrolidinones of the general formula (I): where X represents a hydrogen atom or halogen atom, Y and Z each represents a chlorine atom or bromine atom, and R represents an alkyl group with 2 to 4 carbon atoms, are herbicides useful in rice paddy fields to control weeds therein, especially Echinochloa crusgalli and can be produced subjecting the corresponding 3-dihalogeno compounds to dehalogenation to remove one of the halogen atoms or by cyclizing a 2,2-dihalogenoacetamide derivative represented by the general formula (II) under the presence of an appropriate catalyst; in which X, Y, Z and R respectively have the same meanings as described above.

  通式(I)的 1-(3-取代苄基)-3-卤代-4-(1-卤代烷基)-2-吡咯烷酮： 其中 X 代表氢原子或卤素原子，Y 和 Z 分别代表氯原子或溴原子，R 代表具有 2 至 4 个碳原子的烷基，这些除草剂可用于水稻田控制其中的杂草，特别是 Echinochloa crusgalli； 其中 X、Y、Z 和 R 分别具有与上述相同的含义。
• PROCESS FOR PRODUCING AMINE COMPOUNDS
  申请人：Monash University

  公开号：US20150183724A1

  公开（公告）日：2015-07-02

  The present invention provides processes for producing amine compounds. The amine compounds include diammonium compounds and amino acid derivatives.
• US5114466A
  申请人：——

  公开号：US5114466A

  公开（公告）日：1992-05-19