(E)-Methyl 2-[2-hydroxyphenyl]-3-methoxypropenoate

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (E)-Methyl 2-[2-hydroxyphenyl]-3-methoxypropenoate
• 英文别名: (E)-methyl 2-(2'-hydroxyphenyl)-3-methoxyacrylate；methyl 2-(2-hydroxyphenyl)-3-methoxy-acrylate；Methyl 2-(2-hydroxyphenyl)-3-methoxyacrylate；methyl (Z)-2-(2-hydroxyphenyl)-3-methoxyprop-2-enoate
• 化学式: C₁₁H₁₂O₄
• 分子量: 208.214
• InChiKey: CUEDLSLTSIRGCF-CLFYSBASSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.6
• 重原子数：
  15
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.18
• 拓扑面积：
  55.8
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  (E)-Methyl 2-[2-hydroxyphenyl]-3-methoxypropenoate 在 4-二甲氨基吡啶 作用下， 以 甲苯 、 苯甲酰异氰酸脂 为溶剂， 生成 (E)-methyl 2-[2-((benzoyl)carbamoyloxy)phenoxy]-3-methoxypropenoate
  参考文献：
  名称：

  Fungicides

  摘要：

  一种化合物的化学式为：##STR1##，在制备杀菌剂时作为中间体有用。

  公开号：

  US05585513A1

文献信息

• Oxa- and thiadiazole derivatives
  申请人：Zeneca Limited

  公开号：US05438066A1

  公开（公告）日：1995-08-01

  Fungicidal and insecticidal compounds having the general formula (I): ##STR1## or a stereoisomer thereof, wherein A is CH or N; B is OCH.sub.3 or NHCH.sub.3 ; one of L and M is N and the other is S or O; X is an optionally substituted carbocyclic or heterocyclic group; and n is 0 or 1.

  具有通式（I）的杀真菌和杀虫化合物：其中A为CH或N；B为OCH3或NHCH3；L和M中的一个为N，另一个为S或O；X为可选取代的碳环或杂环基团；n为0或1。
• Pyrimidine derivatives useful as fungicides
  申请人：Imperial Chemical Industries PLC

  公开号：US05059605A1

  公开（公告）日：1991-10-22

  Fungicidal compounds having the formula (I): ##STR1## in which any two of K, L and M are nitrogen and the other is CE; X and Y are independently hydrogen, halogen, C.sub.1-4 alkyl, C.sub.3-6 cycloalkyl, C.sub.2-4 alkenyl, C.sub.2-4 alkynyl, C.sub.2-4 alkenyloxy, C.sub.2-4 alkynyloxy, phenyl, benzyloxy, cyano, isocyano, isothiocyanato, nitro, NR.sup.1 R.sup.2, NR.sup.1 OR.sup.2, N.sub.3, NHCOR.sup.1, NR.sup.1 CO.sub.2 R.sup.2, NHCONR.sup.1 R.sup.2, N.dbd.CHNR.sup.1 R.sup.2, NHSO.sub.2 R.sup.1, OR.sup.1, OCOR.sup.1, OSO.sub.2 R.sup.1, SR.sup.1, SOR.sup.1, SO.sub.2 R.sup.1, SO.sub.2 OR.sup.1, SO.sub.2 NR.sup.1 R.sup.2, COR.sup.1, CR.sup.1 .dbd.NOR.sup.2, CHR.sup.1 CO.sub.2 R.sup.2, CO.sub.2 R.sup.2, CO.sub.2 R.sup.1, CONR.sup.1 R.sup.2, CSNR.sup.1 R.sup.2, CH.sub.3 O.sub.2 C.C:CH.OCH.sub.3, 1-(imidazol-1-yl)vinyl, a 5-membered heterocyclic ring containing one, two or three nitrogen heteroatoms, or a 5- or 6-membered heterocyclic ring containing one or two oxygen or sulphur heteroatoms, optionally a nitrogen heteroatom and optionally one or two oxo or thioxo substituents; or X and Y, when ortho to one another, join to form a 5- or 6-membered aliphatic or aromatic ring optionally containing one or two oxygen, sulphur or nitrogen atoms or one, two or three nitrogen or sulphur atoms; A, B, E, G and U are independently hydrogen, halogen, C.sub.1-4 alkyl, C.sub.1-4 alkoxy, cyano, nitro or trifluoromethyl; and R.sup.1 and R.sup.2 are independently hydrogen, C.sub.1-4 alkyl, C.sub.2-4 alkenyl or phenyl; the aliphatic moieties of any of the foregoing being optionally substituted with one or more of halogen, cyano, OR.sup.1, SR.sup.1, NR.sup.1 R.sup.2, SiR.sup.1.sub.3 or OCOR.sup.1 and the phenyl moieties of any of the foregoing being optionally substituted with one or more of halogen, C.sub.1-4 alkyl, C.sub.1-4 alkoxy, nitro or cyano; and their pyridine N-oxides and N-alkyl pyridinium salts.

  化合物具有以下式子（I）：##STR1## 其中K、L和M中的任意两个为氮，另一个为CE；X和Y独立地为氢、卤素、C.sub.1-4烷基、C.sub.3-6环烷基、C.sub.2-4烯基、C.sub.2-4炔基、C.sub.2-4烯氧基、C.sub.2-4炔氧基、苯基、苄氧基、氰基、异氰基、异硫氰酸酯基、硝基、NR.sup.1 R.sup.2、NR.sup.1 OR.sup.2、N.sub.3、NHCOR.sup.1、NR.sup.1 CO.sub.2 R.sup.2、NHCONR.sup.1 R.sup.2、N.dbd.CHNR.sup.1 R.sup.2、NHSO.sub.2 R.sup.1、OR.sup.1、OCOR.sup.1、OSO.sub.2 R.sup.1、SR.sup.1、SOR.sup.1、SO.sub.2 R.sup.1、SO.sub.2 OR.sup.1、SO.sub.2 NR.sup.1 R.sup.2、COR.sup.1、CR.sup.1 .dbd.NOR.sup.2、CHR.sup.1 CO.sub.2 R.sup.2、CO.sub.2 R.sup.2、CO.sub.2 R.sup.1、CONR.sup.1 R.sup.2、CSNR.sup.1 R.sup.2、CH.sub.3 O.sub.2 C.C:CH.OCH.sub.3、1-（咪唑-1-基）乙烯基、含有一个、两个或三个氮杂原子的5元杂环、或含有一个或两个氧或硫杂原子、可选一个氮杂原子和可选一个或两个氧代或硫代取代基的5-或6元杂环，或当X和Y在相对位置时，它们结合形成一个5-或6元的脂肪族或芳香族环，可选含有一个或两个氧、硫或氮原子或一个、两个或三个氮或硫原子；A、B、E、G和U独立地为氢、卤素、C.sub.1-4烷基、C.sub.1-4烷氧基、氰基、硝基或三氟甲基；R.sup.1和R.sup.2独立地为氢、C.sub.1-4烷基、C.sub.2-4烯基或苯基；上述任何脂肪族均可选择地被一个或多个卤素、氰基、OR.sup.1、SR.sup.1、NR.sup.1 R.sup.2、SiR.sup.1.sub.3或OCOR.sup.1取代，上述任何苯基均可选择地被一个或多个卤素、C.sub.1-4烷基、C.sub.1-4烷氧基、硝基或氰基取代；以及它们的吡啶N-氧化物和N-烷基吡啶盐。
• 3-methoxy-phenyl-acrylic acid methyl esters
  申请人：Bayer Aktiengesellschaft

  公开号：US05773445A1

  公开（公告）日：1998-06-30

  The application describes new 3-methoxy-2-phenyl-acrylic esters of the formula (I) ##STR1## in which R and Y have the meanings given in the description, a process for their preparation, and their use as pesticides.

  该申请描述了公式（I）中的新的3-甲氧基-2-苯基-丙烯酸酯物： ##STR1## 其中R和Y的含义如描述中所给，一种制备它们的方法以及它们作为杀虫剂的用途。
• Pyrimidine fungicides
  申请人：Zeneca Limited

  公开号：US05723471A1

  公开（公告）日：1998-03-03

  A fungicidal compound of formula (I) or a stereoisomer thereof, wherein R is H or CH.sub.3, A is CH or N, and B is OCH.sub.3 or NHCH.sub.3. ##STR1##

  一种杀真菌化合物的公式（I）或其立体异构体，其中R为H或CH.sub.3，A为CH或N，B为OCH.sub.3或NHCH.sub.3。 ##STR1##
• FUNGICIDES
  申请人：——

  公开号：US20040092746A1

  公开（公告）日：2004-05-13

  The invention provides fungicidal compounds of formula (I) or stereoisomers thereof: 1 wherein X is CH 2 O; A is hydrogen; E is hydrogen; q is 1; any two of K, L and M are nitrogen and the other is CH; T is oxygen or sulfur; and Z is an optionally substituted phenyl group or an optionally substituted heterocyclyl group.

  该发明提供了式（I）或其立体异构体的杀真菌化合物：1其中X为CH2O；A为氢；E为氢；q为1；K、L和M中的任意两个为氮，另一个为CH；T为氧或硫；Z为可选取代的苯基或可选取代的杂环基。