benzoic acid 1-tert-butoxy-2,2,6,6-tetramethyl-1-piperidin-4-yl ester

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: benzoic acid 1-tert-butoxy-2,2,6,6-tetramethyl-1-piperidin-4-yl ester
• 英文别名: 4-benzoyloxy-1-tert-butoxy-2,2,6,6-tetramethylpiperidine；4-Benzoyloxy-1-t-butoxy-2,2,6,6-tetramethylpiperidine；[2,2,6,6-tetramethyl-1-[(2-methylpropan-2-yl)oxy]piperidin-4-yl] benzoate
• 化学式: C₂₀H₃₁NO₃
• 分子量: 333.471
• InChiKey: SXHHPAPPGSQBSG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.6
• 重原子数：
  24
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.65
• 拓扑面积：
  38.8
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  4-(benzyloxycarbonyl)-2,2,6,6-tetramethylpiperidine-1-oxyl 、 溴代叔丁烷 在 O-叔丁基羟胺 、 三(三甲基硅基)硅烷 作用下， 以 苯 为溶剂， 以27%的产率得到benzoic acid 1-tert-butoxy-2,2,6,6-tetramethyl-1-piperidin-4-yl ester
  参考文献：
  名称：

  N-烷氧基胺合成的新方法。

  摘要：

  [反应：见正文]我们报告了一种合成N-烷氧基胺的新方法，该方法可用作“活性”自由基聚合反应的引发剂。从卤代烷中提取甲硅烷基可以使其他方法无法合成N-烷氧基胺。

  DOI：

  10.1021/ol049271v

文献信息

• Eclipsed ground-state conformations of the tert-butyl-X bond in N-tert-butoxy- and N-neopentyl-2,2,6,6-tetramethylpiperidine. X-ray crystal structure determinations and molecular mechanics calculations
  作者：J. Edgar Anderson、Derek A. Tocher、John E. T. Corrie、Lodovico Lunazzi

  DOI：10.1021/ja00062a012

  日期：1993.5

  X-ray crystallographic studies of derivatives of N-methoxy- and N-tert-butoxy-2,2,6,6-tetramethylpiperidine show that as expected the N-O bond is staggered with respect to the C-H bonds of the methoxy group in the former case, yet it eclipses a C-methyl bond of the tert-butyl group in the latter case. Molecular mechanics calculations confirm this and show that likewise the preferred conformation of

  N-甲氧基-和 N-叔丁氧基-2,2,6,6-四甲基哌啶衍生物的 X 射线晶体学研究表明，正如预期的那样，NO 键相对于前者中甲氧基的 CH 键是交错的在后一种情况下，它使叔丁基的 C-甲基键黯然失色。分子力学计算证实了这一点，并表明同样优选的 N-新戊基-2,2,6,6-四甲基哌啶构象的 CH 2 与叔丁基键重叠，而在相应的 N-乙基化合物中，CH 2 与甲基键是交错的。报告了所有这些分子的四甲基环己基类似物和轴向构象的计算
• O-substituted N-hydroxy hindered amine stabilizers
  申请人：Ciba-Geigy Corporation

  公开号：US05204473A1

  公开（公告）日：1993-04-20

  Hindered amines based on various 2,2,6,6-tetraalkylated nitrogen-containing heterocyclic moieties wherein the hindered nitrogen atom on the ring is substituted with OR.sub.1 substituents and the 4-position of the ring is substituted with a variety of groups, are effective as light stabilizers in diverse substrate systems.

  基于不同的2,2,6,6-四烷基氮杂环基团的受阻胺，其中环上的受阻氮原子被取代为OR.sub.1基团，环的4位被取代为多种基团，可作为各种基质系统中的光稳定剂。
• N-substituted hindered amine stabilizers
  申请人：CIBA-GEIGY AG

  公开号：EP0309402A1

  公开（公告）日：1989-03-29

  Hindered amines based on various .2,2,6;6-tetcaalkylated nitrogen-containing heterocyclic moieties wherein the hindered nitrogen atom on the ring is substituted with OR1 substituents and the 4-position of the ring is substituted with a variety of groups, are effective as light stabilizers in diverse substrate systems. Some of them are new compounds.

  基于各种.2,2,6;6-四烷基化含氮杂环分子的受阻胺，其中环上的受阻氮原子被 OR1 取代基取代，环的 4 位被各种基团取代，可在各种底物体系中有效地用作光稳定剂。其中一些是新化合物。
• Stabilized monomer compositions
  申请人：CIBA-GEIGY AG

  公开号：EP0467850A1

  公开（公告）日：1992-01-22

  A process for stabilizing an ethylenically unsaturated monomer or oligomer from premature polymerization is disclosed whereby a stabilizing amount of an amine, preferably a substituted hindered amine, in combination with phenothiazine or other related heterocyclic moiety is added to said polymerizable monomer or oligomer. The ethylenically unsaturated monomer or oligomer encompass vinyl monomers or oligomers bearing at least one polymerizable moiety. The combination of substituted hindered amine plus phenothiazine inhibits premature polymerization in the liquid and/or vapor phase.

  本发明公开了一种稳定乙烯基不饱和单体或低聚物使其不过早聚合的工艺，在该工艺中，将稳定量的胺（最好是取代受阻胺）与吩噻嗪或其他相关杂环分子结合添加到所述可聚合单体或低聚物中。乙烯基不饱和单体或低聚物包括含有至少一个可聚合分子的乙烯基单体或低聚物。取代受阻胺和吩噻嗪的组合可抑制液相和/或气相中的过早聚合。
• Chemical Scavenger For Downhole Chemical Analysis
  申请人：Lawrence Jimmy

  公开号：US20120149604A1

  公开（公告）日：2012-06-14

  A method for analyzing formation fluid in a subterranean formation is disclosed, wherein the method includes the steps of: adding a scavenger compound to an analytical reagent to form a reagent solution; collecting an amount of formation fluid into a formation tester, wherein the formation tester includes at least one fluids analyzer comprising at least one probe, at least one flow line, at least one reagent container, and at least one spectral analyzer, wherein the fluids analyzer is configured such that the collected formation fluid is fed through the at least one flow line to the at least one spectral analyzer; mixing an amount of the collected formation fluid with an amount of the reagent solution to form a mixture; and analyzing the mixture downhole.