n-butyl 3,5-di-tert-butyl-4-hydroxybenzoate

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: n-butyl 3,5-di-tert-butyl-4-hydroxybenzoate
• 英文别名: butyl 3,5-di-tert-butyl-4-hydroxybenzoate；Butyl 3,5-ditert-butyl-4-hydroxybenzoate
• 化学式: C₁₉H₃₀O₃
• 分子量: 306.445
• InChiKey: YCOWPKCEXHRGBW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6
• 重原子数：
  22
• 可旋转键数：
  7
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.63
• 拓扑面积：
  46.5
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  n-butyl 3,5-di-tert-butyl-4-hydroxybenzoate 在 sodium hydride 、 potassium carbonate 、 N,N'-二环己基碳二亚胺 作用下， 以 四氢呋喃 、 正己烷 、 丁酮 为溶剂， 反应 60.5h， 生成 3,5-di-tert-butyl-4-[(23-hydroxy-3,6,9,12,15,18,21-heptaoxatricos-1-yl)oxy]benzoic acid succinimidyl ester
  参考文献：
  名称：

  Cyclodextrin-Isolated Alkynylpyrenes as UV-Stable and Blue-Light-Emitting Molecules Even in Condensed States

  摘要：

  Encapsulation of highly emissive alkynylpyrenes with permethylated alpha-cyclodextrin (PM-alpha-CD) followed by capping reaction yielded alkynylpyrene-based [3]rotaxanes. The [3]rotaxane emitted only blue light of monomeric pyrene under various circumstances such as lipophilic, hydrophilic, and even condensed states and exhibited extremely high stability for UV irradiation. These properties would result because PM-alpha-CD, like bulletproof glass, protected the alkynylpyrene core from the attack of another excited alkynylpyrene and singlet oxygen generated by the energy transfer from the excited alkynylpyrene.

  DOI：

  10.1021/acs.orglett.6b00420
• 作为产物：
  描述：

  3,5-二叔丁基-4-羟基苯甲酸 、 正丁醇 在 硫酸 作用下， 生成 n-butyl 3,5-di-tert-butyl-4-hydroxybenzoate
  参考文献：
  名称：

  通过3,5-取代断开对羟基苯甲酸酯的雌激素受体结合特性和抗菌特性

  摘要：

  在商业上用来对羟基苯甲酸酯被用于它们的抗微生物性质，但是弱的结合雌激素受体α（ER α）可以导致乳腺癌在一些应用中。对羟基苯甲酸酯支架的修饰应允许断开这些观察到的特性。为了实现这一目标，各种3,5-取代的对羟基苯甲酸酯的合成和评价了针对抗微生物性质的金黄色葡萄球菌以及竞争性结合至ER α。最小抑菌浓度测定法证实了许多这些衍生物中都保留了抗菌活性，而所有化合物均表现出降低的异雌激素活性，这是通过竞争性酶联免疫吸附测定（ELISA），增殖和雌激素受体结合测定法的组合确定的。因此，对羟基苯甲酸酯支架的这些变化已导致具有对羟基苯甲酸酯衍生物的抗微生物特性的许多对羟基苯甲酸酯衍生物的活性高达母对羟基苯甲酸酯的十六倍，并且没有或显着降低了潜在的引起乳腺癌的特性。

  DOI：

  10.1021/acsmedchemlett.7b00431

文献信息

• LUBRICANT OIL AND LUBRICATING OIL ADDITIVE CONCENTRATE COMPOSITIONS
  申请人：Albemarle Corporation

  公开号：EP1979448A1

  公开（公告）日：2008-10-15
• Lubricant Oil and Lubricating Oil Additive Concentrate Compositions
  申请人：Gatto Vincent J.

  公开号：US20080318814A1

  公开（公告）日：2008-12-25

  A lubricant oil composition having a synergistic oxidative stability is disclosed, the composition comprising at least one hindered phenolic antioxidant, at least one mono-boronated hindered phenolic antioxidant, at least one di-boronated hindered phenolic antioxidant, and at least one alkylated diphenylamine. The invention also provides a lubricating oil additive concentrate composition that imparts synergistic oxidative stability to a lubricant oil upon its addition, the concentrate composition comprising at least one hindered phenolic antioxidant, at least one mono-boronated hindered phenolic antioxidant, at least one di-boronated hindered phenolic antioxidant, and at least one alkylated diphenylamine. Further, the concentrate compositions of the present invention may also be prepared with a high concentration of hindered phenolic antioxidants without deleterious effects on viscosity or lubricant solubility.
• RESIN COMPOSITION FOR LASER ENGRAVING, RELIEF PRINTING PLATE PRECURSOR FOR LASER ENGRAVING AND METHOD FOR PRODUCING THE SAME, AND RELIEF PRINTING PLATE AND METHOD FOR MAKING THE SAME
  申请人：YOSHIDA Kenta

  公开号：US20110076613A1

  公开（公告）日：2011-03-31

  A resin composition for laser engraving, including at least a phenol derivative (A) represented by the following Formula (A), a binder polymer (B), and a crosslinking agent (C), wherein the content of the phenol derivative (A) with respect to the total solid content of the resin composition is from 5% by mass to 50% by mass:
• US4474670A
  申请人：——

  公开号：US4474670A

  公开（公告）日：1984-10-02
• US4507216A
  申请人：——

  公开号：US4507216A

  公开（公告）日：1985-03-26