(E)-3-(2,4-dimethoxyphenyl)-2-methylacrylaldehyde

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 肉桂醛
• 英文名称: (E)-3-(2,4-dimethoxyphenyl)-2-methylacrylaldehyde
• 英文别名: (E)-3-(2,4-dimethoxyphenyl)-2-methylprop-2-enal
• 化学式: C₁₂H₁₄O₃
• 分子量: 206.241
• InChiKey: WGDAGMZWJKFZGW-RMKNXTFCSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  15
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  35.5
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  异丁醛 、 间苯二甲醚 在 dipotassium peroxodisulfate 、 palladium diacetate 、 三氟乙酸 、 β-丙氨酸 作用下， 以 乙腈 为溶剂， 反应 24.0h， 以52%的产率得到(E)-3-(2,4-dimethoxyphenyl)-2-methylacrylaldehyde
  参考文献：
  名称：

  Dehydrogenative β-Arylation of Saturated Aldehydes Using Transient Directing Groups

  摘要：

  An unprecedented cross-dehydrogenative-coupling (CDC) reaction of saturated aldehyde beta-C-H with arenes to form cinnamaldehydes via the cleavages of four C-H bonds has been developed. The reaction possesses complete E-stereoselectivity for the C = C double bond. The protocol is featured by atom and step economy, mild reaction conditions, and convenient operation.

  DOI：

  10.1021/acs.orglett.9b00695

文献信息

• COMPOSITION FOR INHIBITING FEEDING OF WEEVILS
  申请人：Forskarpatent I SYD

  公开号：EP1294229A1

  公开（公告）日：2003-03-26
• [EN] COMPOSITION FOR INHIBITING FEEDING OF WEEVILS<br/>[FR] COMPOSITION POUR EMPECHER DES CHARANÇONS DE S'ALIMENTER
  申请人：FORSKARPATENT I SYD

  公开号：WO2002000022A1

  公开（公告）日：2002-01-03

  The present invention relates to a Composition containing a gnawing inhibiting compound and intended to be applied on conifer saplings, in particular pine saplings, to prevent weevil to attack the young stem, wherein the gnawing inhibiting compound is present in a bound form to a substance of the group of zeolites, cyclodextrines, homogenous porous microspheres, spherical vesicles, hollow fibres, such as textile fibres (wool) capillaries of synthetic material (polymers), starch, and polymer films, optionally in combination with a carrier, whereby the gnawing inhibiting compound is present in an amount of 1 to 10 % by weight, as well as gnawing inhibiting compounds.
• [EN] COMPOSITION FOR INHIBITING GNAWING AND FEEDING BY INSECTS AND ANIMALS INTENDED TO BE APPLIED ON SEEDLINGS AND TREES<br/>[FR] COMPOSITION DESTINEE A ETRE APPLIQUEE SUR DES SEMIS ET DES ARBRES PERMETTANT D'EMPECHER QUE DES INSECTES OU DES ANIMAUX RONGENT OU SE NOURRISSENT DESDITS SEMIS ET ARBRES
  申请人：FORSKARPATENT I SYD AB

  公开号：WO2004002224A1

  公开（公告）日：2004-01-08

  The invention relates to a composition for inhibiting gnawing and feeding by insects and animals intended to be applied on seedlings and trees comprising a corrosion inhibiting composition of the type containing wax and/or bitumen dissolved in a petroleum base or in a water soluble base, optionally, in combination with an antifeedant compound in a bound form, and the use thereof.
• Dehydrogenative β-Arylation of Saturated Aldehydes Using Transient Directing Groups
  作者：Xing-Long Zhang、Gao-Fei Pan、Xue-Qing Zhu、Rui-Li Guo、Ya-Ru Gao、Yong-Qiang Wang

  DOI：10.1021/acs.orglett.9b00695

  日期：2019.4.19

  An unprecedented cross-dehydrogenative-coupling (CDC) reaction of saturated aldehyde beta-C-H with arenes to form cinnamaldehydes via the cleavages of four C-H bonds has been developed. The reaction possesses complete E-stereoselectivity for the C = C double bond. The protocol is featured by atom and step economy, mild reaction conditions, and convenient operation.