hexadecyl(phenyl)phosphinic acid

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: hexadecyl(phenyl)phosphinic acid
• 化学式: C₂₂H₃₉O₂P
• 分子量: 366.524
• InChiKey: KUFCXHOQNRXCDT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.2
• 重原子数：
  25
• 可旋转键数：
  16
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.73
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  十六碳烯 、 苯膦酸 以 1,4-二氧六环 为溶剂， 反应 1.0h， 以79%的产率得到hexadecyl(phenyl)phosphinic acid
  参考文献：
  名称：

  Rapid and Efficient Microwave-Assisted Hydrophosphinylation of Unactivated Alkenes with H-Phosphinic Acids without Added Metal or Radical Initiator

  摘要：

  A microwave-assisted hydrophosphinylation of unactivated alkenes with phosphinic acid and its derivatives under metal-free and initiator-free conditions is reported. Such hydrophosphinylations are operationally simple, use aqueous hypophosphorus acid, H-phenylphosphinic acid, and H-alkylphosphinic acids, and seem to proceed by a radical mechanism. Good isolated yields were obtained using a reasonable excess of the appropriate reagent.

  DOI：

  10.1055/s-0035-1560209

文献信息

• US6956072B1
  申请人：——

  公开号：US6956072B1

  公开（公告）日：2005-10-18
• Rapid and Efficient Microwave-Assisted Hydrophosphinylation of Unactivated Alkenes with H-Phosphinic Acids without Added Metal or Radical Initiator
  作者：Stamatia Vassiliou、Panagiota Troupa、Georgia Katsiouleri

  DOI：10.1055/s-0035-1560209

  日期：——

  A microwave-assisted hydrophosphinylation of unactivated alkenes with phosphinic acid and its derivatives under metal-free and initiator-free conditions is reported. Such hydrophosphinylations are operationally simple, use aqueous hypophosphorus acid, H-phenylphosphinic acid, and H-alkylphosphinic acids, and seem to proceed by a radical mechanism. Good isolated yields were obtained using a reasonable excess of the appropriate reagent.