N-[(E)-1-pyridin-2-ylethylideneamino]-1H-benzimidazol-2-amine

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并咪唑类
• 英文名称: N-[(E)-1-pyridin-2-ylethylideneamino]-1H-benzimidazol-2-amine
• 化学式: C₁₄H₁₃N₅
• 分子量: 251.29
• InChiKey: WDIILZOTCNLNBN-VCHYOVAHSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  19
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.07
• 拓扑面积：
  66
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• Zinc complexes of hydrazones and (thio)semicarbazones and their use for the treatment of cancer
  申请人：RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY

  公开号：US10729671B2

  公开（公告）日：2020-08-04

  The invention provides complexes of Zn2+ of formulae (la) and (IIa) that are useful for treating cancer, as well as compositions and kits comprising such complexes.

  本发明提供了可用于治疗癌症的式 (la) 和 (IIa) 的 Zn2+ 复合物，以及包含此类复合物的组合物和试剂盒。
• ZINC COMPLEXES OF HYDRAZONES AND (THIO)SEMICARBAZONES AND THEIR USE FOR THE TREATMENT OF CANCER
  申请人：RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY

  公开号：US20180000772A1

  公开（公告）日：2018-01-04

  The invention provides complexes of Zn2+ of formulae (la) and (IIa) that are useful for treating cancer, as well as compositions and kits comprising such complexes.
• [EN] ZINC COMPLEXES OF HYDRAZONES AND (THIO)SEMICARBAZONES AND THEIR USE FOR THE TREATMENT OF CANCER<br/>[FR] COMPLEXES ZINC D'HYDRAZONES ET DE (THIO)SEMICARBAZONES ET LEUR UTILISATION POUR LE TRAITEMENT DU CANCER
  申请人：UNIV RUTGERS

  公开号：WO2016123250A1

  公开（公告）日：2016-08-04

  The invention provides complexes of Zn2+ of formulae (la) and (IIa) that are useful for treating cancer, as well as compositions and kits comprising such complexes.