1,1'-[1,4-phenylenebis(methylene)]bis-4,4'-bipyridinium

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 1,1'-[1,4-phenylenebis(methylene)]bis-4,4'-bipyridinium
• 英文别名: 1,1''-(1,4-Phenylenebis(methylene))bis(([4,4'-bipyridin]-1-ium))；4-pyridin-4-yl-1-[[4-[(4-pyridin-4-ylpyridin-1-ium-1-yl)methyl]phenyl]methyl]pyridin-1-ium
• 化学式: C₂₈H₂₄N₄
• 分子量: 416.525
• InChiKey: HMGNIPIZYSIFCH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.3
• 重原子数：
  32
• 可旋转键数：
  6
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.07
• 拓扑面积：
  33.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  1,1'-[1,4-phenylenebis(methylene)]bis-4,4'-bipyridinium 在 N,N'-二环己基碳二亚胺 、 间苯二甲醚 作用下， 以 乙腈 为溶剂， 反应 173.0h， 生成
  参考文献：
  名称：

  Molecular recognition at the electrode-solution interface. Design, self-assembly, and interfacial binding properties of a molecular sensor

  摘要：

  DOI：

  10.1021/ja00126a041
• 作为产物：
  描述：

  1,4-二(溴甲基)苯 、 4,4'-联吡啶 在 ammonium hexafluorophosphate 作用下， 以 乙腈 、 水 为溶剂， 反应 20.0h， 生成 1,1'-[1,4-phenylenebis(methylene)]bis-4,4'-bipyridinium
  参考文献：
  名称：

  无环葫芦[n]uril受体腔内联吡啶客体的络合

  摘要：

  摘要 合成了一系列双吡啶客体，并通过核磁共振、紫外-可见光谱和 X 射线衍射研究了它们与无环 CB[n] 型受体的包合物。新型 [3] 假轮烷是通过 CH ... O、π-π 和离子-偶极相互作用形成的。还通过紫外-可见-近红外和 EPR 光谱研究了它们的络合对双吡啶鎓阳离子自由基单体和二聚体之间平衡的影响。在还原时，通过柔性戊烯链连接的联吡啶鎓单元在无环 CB[n] 型受体存在下更倾向于形成二聚体，而那些通过刚性二甲苯桥连接的联吡啶单元由于空间效应而被抑制为单体形式。图形概要

  DOI：

  10.1080/10610278.2019.1622702

文献信息

• Synthesis of non-symmetric viologen-containing ditopic ligands and their Pd(<scp>ii</scp>)/Pt(<scp>ii</scp>)-directed self-assembly
  作者：Olaya Domarco、Iago Neira、Tamara Rama、Arturo Blanco-Gómez、Marcos D. García、Carlos Peinador、José M. Quintela

  DOI：10.1039/c7ob00161d

  日期：——

  non-symmetric viologen-containing ditopic ligands, as well as the Pd(II)/Pt(II)-directed self-assembly of some of these into metallacyclic receptors. The designed synthetic route, that implies the sequential alkylation and the Zincke reaction of activated bipyridinium salts, allowed us to substantially improve the yield in the preparation of three previously reported ligands. The versatility and efficiency

  我们在这里提出了一种有效的方法，用于制备非对称的含紫精的二位配体，以及其中一些以Pd（II）/ Pt（II）定向的自组装成金属环受体。设计的合成路线暗示了活化的联吡啶鎓盐的顺序烷基化和Zincke反应，这使我们能够在制备三种先前报道的配体时大幅提高收率。还测试了该方法的多功能性和效率，可用于制备四种结构特征非常不同的新的含紫精配体。此外，Pd（II）和Pt（II）周围新配体的自组装）中心已经过测试，可产生具有不同尺寸和电子特性的单核矩形金属环。
• ANALYTE DETECTION USING NEAR-INFRARED FLUOROPHORES
  申请人：Portland State University

  公开号：US20160223558A1

  公开（公告）日：2016-08-04

  Embodiments of compounds for selectively detecting an analyte are disclosed, along with methods and kits for detecting analytes with the compounds. The compounds are bridged viologen conjugates including at least one fluorophore according to the general structure At least one of R 1 /R 2 , R 2 /R 3 , R 3 /R 4 , R 5 /R 6 , R 6 /R 7 , and/or R 7 /R 8 together form a substituted or unsubstituted cycloalkyl or aryl.

  公开了用于选择性检测分析物的化合物实施例，以及使用这些化合物检测分析物的方法和试剂盒。这些化合物是包括至少一种荧光团的桥联紫罗兰类化合物，其一般结构如下：至少有R1/R2、R2/R3、R3/R4、R5/R6、R6/R7和/或R7/R8中的至少一对形成取代或未取代的环烷基或芳基。
• Host–guest interactions of a twisted cucurbit[15]uril with paraquat derivatives and bispyridinium salts
  作者：Qing Li、Jiong Zhou、Jifu Sun、Jie Yang

  DOI：10.1016/j.tetlet.2019.151022

  日期：2019.9

  Host–guest complexations of a twisted cucurbit[15]uril with some paraquat derivatives and bispyridinium salts in aqueous solution are investigated by nuclear magnetic resonance, UV–vis spectrometry and isothermal titration calorimetry. These complexations are mainly enthalpy-driven.

  通过核磁共振，紫外可见分光光度法和等温滴定量热法研究了扭曲的葫芦[15]尿素与某些百草枯衍生物和双吡啶鎓盐在水溶液中的主客体络合物。这些复杂性主要是由焓驱动的。
• THIOL DETECTION
  申请人：Strongin Robert Michael

  公开号：US20120276649A1

  公开（公告）日：2012-11-01

  Embodiments of compounds for selectively detecting a thiol are disclosed. In some embodiments, the compounds are bridged viologens, and the compounds are capable of reacting with homocysteine and/or glutathione in a buffered solution to produce a change in the solution's absorbance spectrum and/or emission spectrum. Also disclosed are embodiments of methods and kits for detecting homocysteine and/or glutathione with the disclosed bridged viologens.

  本发明揭示了用于选择性检测巯基的化合物实施例。在某些实施例中，这些化合物是桥联苯并咪唑化合物，它们能够与缓冲溶液中的同型半胱氨酸和/或谷胱甘肽发生反应，产生溶液吸收光谱和/或发射光谱的变化。本发明还揭示了使用上述桥联苯并咪唑化合物检测同型半胱氨酸和/或谷胱甘肽的方法和试剂盒实施例。
• Turning on Resonant SERRS Using the Chromophore−Plasmon Coupling Created by Host−Guest Complexation at a Plasmonic Nanoarray
  作者：Edward H. Witlicki、Sissel S. Andersen、Stinne W. Hansen、Jan O. Jeppesen、Eric W. Wong、Lasse Jensen、Amar H. Flood

  DOI：10.1021/ja910155b

  日期：2010.5.5

  An active molecular plasmonics system is demonstrated where a supramolecular chromophore generated in a host guest binding event couples with the localized surface plasmon resonance (LSPR) arising from gold nanodisc gratings. This coupling was achieved by wavelength-matching the chromophore and the LSPR with the laser excitation, thus giving rise to surface-enhanced resonance Raman scattering (SERRS). The chromophore is a broad charge-transfer (CT) band centered at 865 nm (epsilon = 3500 M-1 cm(-1)) generated by the complexation of cyclobis(paraquat-p-phenylene) (CBPQT(4+)) and the guest molecule tetrathiafulvalene (TTF). The substrates consist of sub-1-mu m gold nanodisc arrays which display dimension-tunable plasmon wavelengths (600-1000 nm). The vibrational spectra of the complex arising from SERRS (lambda(exc) = 785 nm) were generated by irradiating an array (lambda(LSPR) = 765 nm) through the solution to give a chromophore-specific signature with the intensities surface enhanced by similar to 10(5). Surface adsorption of the empty and complexed CBPQT(4+) is also implicated in bringing the chromophore into the electric field arising from the surface-localized plasmon. In a titration experiment, the SERRS effect was then used to verify the role of resonance in turning on the spectrum and to accurately quantify the binding between surface-adsorbed CBPQT(4+) and TTF. The use of a nonpatterned gold substrate as well as a color mismatched complex did not show the enhancement, thus validating that spectral overlap between the chromophore and plasmon resonance is key for resonance surface enhancement. Simulations of the electric fields of the arrays are consistent with interdisc plasmon coupling and the observed enhancement factors. The creation of a responsive plasmonic device upon the addition of the guest molecule and the subsequent coupling of the CT chromophore to the plasmon presents favorable opportunities for applications in molecular sensing and active molecular plasmonics.