tert-butyl 1-ethyl-8-hydroxy-2-oxo-4,5-dihydro-3H-1-benzazepine-3-carboxylate

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯氮卓类
• 英文名称: tert-butyl 1-ethyl-8-hydroxy-2-oxo-4,5-dihydro-3H-1-benzazepine-3-carboxylate
• 化学式: C₁₇H₂₃NO₄
• 分子量: 305.4
• InChiKey: JWTXVTYEMOOLOR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  22
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.53
• 拓扑面积：
  66.8
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• Substituted 1-benzazepines and derivatives thereof
  申请人：Tomazic Alenka

  公开号：US20050234041A1

  公开（公告）日：2005-10-20

  This invention relates to substituted 1-benzazepines and derivatives thereof useful as anti-infective agents, to compositions, including pharmaceutical compositions, comprising such compounds, to processes for making these compounds and to methods of using these compounds for killing bacteria and other microorganisms or inhibiting bacterial and other microorganism growth.

  本发明涉及取代的1-苯并氮杂环和其衍生物，其作为抗感染剂有用，包括制备这些化合物的组合物，包括药物组合物，制备这些化合物的过程以及使用这些化合物杀死细菌和其他微生物或抑制细菌和其他微生物生长的方法。
• EP1392317A4
  申请人：——

  公开号：EP1392317A4

  公开（公告）日：2005-10-19
• SUBSTITUTED 1-BENZAZEPINES AND DERIVATIVES THEREOF
  申请人：Antexpharma, Inc.

  公开号：EP1392317A2

  公开（公告）日：2004-03-03
• [EN] SUBSTITUTED 1-BENZAZEPINES AND DERIVATIVES THEREOF<br/>[FR] 1-BENZAZEPINES SUBSTITUEES ET LEURS DERIVES
  申请人：ANTEXPHARMA INC

  公开号：WO2002100327A2

  公开（公告）日：2002-12-19

  This invention relates to substituted 1-benzazepines and derivatives thereof useful as anti-infective agents, to compositions, including pharmaceutical compositions, comprising such compounds, to processes for making these compounds and to methods of using these compounds for killing bacteria and other microorganisms or inhibiting bacterial and other microorganism growth,