N-(hex-1-en-4-yl)-2,6-dimethylaniline | 146469-80-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-(hex-1-en-4-yl)-2,6-dimethylaniline
• 英文别名: N-hex-5-en-3-yl-2,6-dimethylaniline
• CAS: 146469-80-9
• 化学式: C₁₄H₂₁N
• 分子量: 203.327
• InChiKey: SWRSTHLKAXDMMI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.7
• 重原子数：
  15
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.43
• 拓扑面积：
  12
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  甲氧基乙酰氯 、 N-(hex-1-en-4-yl)-2,6-dimethylaniline 在 三乙胺 作用下， 以 四氯化碳 为溶剂， 以95%的产率得到N-(2,6-dimethylphenyl)-N-(hex-1-en-4-yl)methoxyacetamide
  参考文献：
  名称：

  An Efficient and Convenient Synthesis of Chain Lengthened Homologs of the Fungicide Metalaxyl

  摘要：

  An efficient and convenient synthesis of chain lengthened homologs of the important fungicide Metalaxyl is described. The starting material utilized is 2,6-dimethylaniline and the sequence is accomplished utilizing Grignard reactions and ruthenium based oxidations to obtain the proper analogs.

  DOI：

  10.1080/00397919208021134
• 作为产物：
  描述：

  2,6-二甲基苯胺 在 3 A molecular sieve 作用下， 以 四氢呋喃 为溶剂， 反应 14.0h， 生成 N-(hex-1-en-4-yl)-2,6-dimethylaniline
  参考文献：
  名称：

  An Efficient and Convenient Synthesis of Chain Lengthened Homologs of the Fungicide Metalaxyl

  摘要：

  An efficient and convenient synthesis of chain lengthened homologs of the important fungicide Metalaxyl is described. The starting material utilized is 2,6-dimethylaniline and the sequence is accomplished utilizing Grignard reactions and ruthenium based oxidations to obtain the proper analogs.

  DOI：

  10.1080/00397919208021134

文献信息

• An Efficient and Convenient Synthesis of Chain Lengthened Homologs of the Fungicide Metalaxyl
  作者：John T. Gupton、James G. Tarrant、Richard H. Yu、Traci L. Solarz、Hak-Fun Chow

  DOI：10.1080/00397919208021134

  日期：1992.12

  An efficient and convenient synthesis of chain lengthened homologs of the important fungicide Metalaxyl is described. The starting material utilized is 2,6-dimethylaniline and the sequence is accomplished utilizing Grignard reactions and ruthenium based oxidations to obtain the proper analogs.