(2-Chloro-4'-methoxy-5,6-dimethyl-biphenyl-3-yl)-trimethyl-silane

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (2-Chloro-4'-methoxy-5,6-dimethyl-biphenyl-3-yl)-trimethyl-silane
• 英文别名: [2-Chloro-3-(4-methoxyphenyl)-4,5-dimethylphenyl]-trimethylsilane
• 化学式: C₁₈H₂₃ClOSi
• 分子量: 318.919
• InChiKey: BRGBTRIYIOGWSZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.18
• 重原子数：
  21
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  Carbonic acid (1Z,3E,5E)-2-chloro-1-(4-methoxy-phenyl)-5-methyl-3-trimethylsilanyl-hepta-1,3,5-trienyl ester ethyl ester 以 二甲基亚砜 为溶剂， 反应 2.0h， 以91%的产率得到(2-Chloro-4'-methoxy-5,6-dimethyl-biphenyl-3-yl)-trimethyl-silane
  参考文献：
  名称：

  Synthesis of functionalized biaryl compounds via ring expansion of alkenylcyclobutenones

  摘要：

  Various functionalized biaryls are accessible via a simple two-step process. Treatment of a] kenylcyclobuten ones with aryllithium provides ring-opened trienes, which are smoothly cycloaromatized under thermal conditions. (C) 2002 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(02)02473-5

文献信息

• Synthesis of functionalized biaryl compounds via ring expansion of alkenylcyclobutenones
  作者：Toshiyuki Hamura、Masato Morita、Takashi Matsumoto、Keisuke Suzuki

  DOI：10.1016/s0040-4039(02)02473-5

  日期：2003.1

  Various functionalized biaryls are accessible via a simple two-step process. Treatment of a] kenylcyclobuten ones with aryllithium provides ring-opened trienes, which are smoothly cycloaromatized under thermal conditions. (C) 2002 Elsevier Science Ltd. All rights reserved.