3-methyl-1-pentyl-pyrrolidine

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡咯烷类
• 英文名称: 3-methyl-1-pentyl-pyrrolidine
• 英文别名: 3-Methyl-1-pentyl-pyrrolidin；3-Methyl-1-pentylpyrrolidine
• 化学式: C₁₀H₂₁N
• 分子量: 155.283
• InChiKey: OJVUICPUZGLSEF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  11
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  3.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  1,4-二氧六环 、 2-甲基-1,4-丁二醇 、 1-氨基戊烷 在 copper oxide-chromium oxide 、 氢气 作用下， 生成 3-methyl-1-pentyl-pyrrolidine
  参考文献：
  名称：

  Pyrrolidines, Piperidines and Hexahydroazepines from Glycols

  摘要：

  DOI：

  10.1021/ja01272a015

文献信息

• SUBSTITUTED FUSED BI- OR TRI- HETEROCYCLIC COMPOUNDS AS EHMT2 INHIBITORS
  申请人：Epizyme Inc

  公开号：EP3519393B1

  公开（公告）日：2022-05-18
• Biarylurea derivatives
  申请人：Hayama Takashi

  公开号：US20070027147A1

  公开（公告）日：2007-02-01

  The present invention relates to a compound of Formula (I) and the manufacturing method(s) thereof and the use thereof: Formula (I) wherein: Ar is a nitrogen-containing heteroaromatic ring group; X and Z are each a carbon atom, and so on; Y is CO, and so on; R 1 is a hydrogen atom, and so on; R 2 and R 3 are each a hydrogen atom, and so on; R 4 and R 5 are each a hydrogen atom, and so on; and the formula is a single bond or a double bond. According to the present invention, the compound of the present invention can provide Cdk4 and/or Cdk6 inhibitors for treating malignant tumors, because the compounds of the present invention exhibit a prominent growth inhibitory activity against tumor cells.
• US7354946B2
  申请人：——

  公开号：US7354946B2

  公开（公告）日：2008-04-08
• Pyrrolidines, Piperidines and Hexahydroazepines from Glycols
  作者：Ralph M. Hill、Homer Adkins

  DOI：10.1021/ja01272a015

  日期：1938.5