5-({2-[(2-chlorobenzyl)oxy]benzyl}amino)-1,3-dihydro-2H-benzimidazol-2-one

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并咪唑类
• 英文名称: 5-({2-[(2-chlorobenzyl)oxy]benzyl}amino)-1,3-dihydro-2H-benzimidazol-2-one
• 英文别名: 5-[[2-[(2-chlorophenyl)methoxy]phenyl]methylamino]-1,3-dihydrobenzimidazol-2-one
• 化学式: C₂₁H₁₈ClN₃O₂
• mdl: MFCD07434576
• 分子量: 379.8
• InChiKey: MICKUTSGRGWCQD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  27
• 可旋转键数：
  6
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.1
• 拓扑面积：
  62.4
• 氢给体数：
  3
• 氢受体数：
  3

文献信息

• Antivirals against molluscum contagiosum virus
  申请人：THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA

  公开号：US10112895B2

  公开（公告）日：2018-10-30

  This invention provides compounds of formulas (I)-(XIV) as defined in the specification, and pharmaceutical compositions comprising the same, and methods of inhibiting, treating, or abrogating a molluscum contagiosum virus infection in a subject using compounds or compositions of the invention:

  本发明提供了说明书中定义的式(I)-(XIV)化合物和包含这些化合物的药物组合物，以及使用本发明化合物或组合物抑制、治疗或消除受试者传染性软疣病毒感染的方法：
• EP3200778A1
  申请人：——

  公开号：EP3200778A1

  公开（公告）日：2017-08-09
• ANTIVIRALS AGAINST MOLLUSCUM CONTAGIOSUM VIRUS
  申请人：THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA

  公开号：US20170217882A1

  公开（公告）日：2017-08-03

  This invention provides compounds of formulas (I)-(XIV) as defined in the specification, and pharmaceutical compositions comprising the same, and methods of inhibiting, treating, or abrogating a molluscum contagiosum virus infection in a subject using compounds or compositions of the invention:
• [EN] ANTIVIRALS AGAINST MOLLUSCUM CONTAGIOSUM VIRUS<br/>[FR] ANTIVIRAUX CONTRE LE VIRUS DU MOLLUSCUM CONTAGIOSUM
  申请人：UNIV PENNSYLVANIA

  公开号：WO2016053893A1

  公开（公告）日：2016-04-07

  This invention provides compounds of formulas (I)--(XIV) as defined in the specification, and pharmaceutical compositions comprising the same, and methods of inhibiting, treating, or abrogating a molluscum contagiosum virus infection in a subject using the compounds or compositions (e.g., compound 10).