2-(3,4-dimethoxybenzyl)-3-furoic acid

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-(3,4-dimethoxybenzyl)-3-furoic acid
• 英文别名: 2-[(3,4-Dimethoxyphenyl)methyl]furan-3-carboxylic acid
• 化学式: C₁₄H₁₄O₅
• 分子量: 262.262
• InChiKey: FOBNOOQGHIZNQT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  19
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.21
• 拓扑面积：
  68.9
• 氢给体数：
  1
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  3-糠酸 在 正丁基锂 、 碘代三甲硅烷 、 二异丙胺 作用下， 以 乙腈 为溶剂， 反应 1.08h， 生成 2-(3,4-dimethoxybenzyl)-3-furoic acid
  参考文献：
  名称：

  The Rapid Reduction of α,α-Diaryl Alcohols To The Corresponding Alkanes Using lodotrimethylsilane

  摘要：

  The utility of iodotrimethylsilane has been extended to include the rapid and highly selective reduction of alpha,alpha-diaryl alcohols. The reduction of a series of alpha-hydroxyfuroic acids in near quantitative yield has been demonstrated and the mechanism discussed.

  DOI：

  10.1080/00397919608003868

文献信息

• The Rapid Reduction of α,α-Diaryl Alcohols To The Corresponding Alkanes Using lodotrimethylsilane
  作者：Philip J Perry、Vasilios H Pavlidis、lan G C Coutts

  DOI：10.1080/00397919608003868

  日期：1996.1

  The utility of iodotrimethylsilane has been extended to include the rapid and highly selective reduction of alpha,alpha-diaryl alcohols. The reduction of a series of alpha-hydroxyfuroic acids in near quantitative yield has been demonstrated and the mechanism discussed.