[1,1':2',1''-terphenyl]-2,6-dicarboxylic acid

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: [1,1':2',1''-terphenyl]-2,6-dicarboxylic acid
• 英文别名: 2-(2-Phenylphenyl)benzene-1,3-dicarboxylic acid
• 化学式: C₂₀H₁₄O₄
• 分子量: 318.329
• InChiKey: OUQANUSBUNRSBU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.7
• 重原子数：
  24
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  74.6
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  [1,1':2',1''-terphenyl]-2,6-dicarboxylic acid 在 甲烷磺酸 作用下， 反应 6.0h， 以72%的产率得到benzo[5,6]cyclohepta[1,2,3,4-def]fluorene-1,5-dione
  参考文献：
  名称：

  通过二溴亚甲基官能化的三苯并azulene的两步脱卤均质偶合，表面合成含Cumulene的聚合物。

  摘要：

  众所周知，Cumulene化合物很难制备和研究，因为它们的反应性随连续双键数量的增加而急剧增加。在这方面，新兴的表面合成领域提供了特殊的机会，因为它依赖于在良好控制的超高真空条件下在干净的金属基材上进行的反应。在这里我们报告了通过连续热活化脱卤CC耦合的带有两个二溴亚甲基基团的三苯并氮杂苯的前驱体，通过Au（111）表面上的枯烯样键连接的聚合物的表面合成。已通过扫描探针显微镜和光谱方法以及X射线光电子能谱，并结合密度泛函理论计算，研究了具有异丙苯样五角形-五边形和七角形-七边形连接的聚合物的结构和电子性能。我们的结果为含异丙苯化合物的表面合成以及与在表面逐步制备碳-碳键相关的方案提供了前景。

  DOI：

  10.1002/anie.202001939
• 作为产物：
  描述：

  2-联苯硼酸 在 potassium permanganate 、 四(三苯基膦)钯 、 potassium carbonate 作用下， 以 1,4-二氧六环 、 水 、 丙酮 为溶剂， 反应 3.0h， 生成 [1,1':2',1''-terphenyl]-2,6-dicarboxylic acid
  参考文献：
  名称：

  通过二溴亚甲基官能化的三苯并azulene的两步脱卤均质偶合，表面合成含Cumulene的聚合物。

  摘要：

  众所周知，Cumulene化合物很难制备和研究，因为它们的反应性随连续双键数量的增加而急剧增加。在这方面，新兴的表面合成领域提供了特殊的机会，因为它依赖于在良好控制的超高真空条件下在干净的金属基材上进行的反应。在这里我们报告了通过连续热活化脱卤CC耦合的带有两个二溴亚甲基基团的三苯并氮杂苯的前驱体，通过Au（111）表面上的枯烯样键连接的聚合物的表面合成。已通过扫描探针显微镜和光谱方法以及X射线光电子能谱，并结合密度泛函理论计算，研究了具有异丙苯样五角形-五边形和七角形-七边形连接的聚合物的结构和电子性能。我们的结果为含异丙苯化合物的表面合成以及与在表面逐步制备碳-碳键相关的方案提供了前景。

  DOI：

  10.1002/anie.202001939

文献信息

• MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME
  申请人：TABATA Masayoshi

  公开号：US20110224343A1

  公开（公告）日：2011-09-15

  The present invention provides a modifier for aromatic polyesters which enhances the melt fluidity of aromatic polyesters without a significant decrease in the heat resistance of the aromatic polyesters, and an aromatic polyester resin composition including the modifier for aromatic polyesters. The present invention relates to a modifier for aromatic polyesters comprising polyhydric phenol residues and residues of aromatic polycarboxylic acid, acid halide or acid anhydride thereof, and the modifier comprises a material having a structure composed of a first residue selected from the group consisting of divalent residues represented by Formula (I): —Ar—W 1 x —Ar— and by Formula (II): —Ar—, the first residues being bonded to two identical or different second residues selected from the group consisting of monovalent residues represented by Formula (III): and monovalent residues represented by Formula (IV): —O—C(O)—R 7 —.

  本发明提供了一种用于芳香族聚酯的改性剂，可以增强芳香族聚酯的熔融流动性，而不明显降低芳香族聚酯的耐热性，以及包括该改性剂的芳香族聚酯树脂组合物。本发明涉及一种用于芳香族聚酯的改性剂，包括多羟基酚残基和芳香族多羧酸、酸卤或其酸酐残基，该改性剂包括具有以下结构的材料：第一残基，选择自由式(I)所代表的二价残基：—Ar—W1x—Ar—和自由式(II)所代表的：—Ar—，第一残基与选择自由式(III)所代表的单价残基：和自由式(IV)所代表的单价残基：—O—C(O)—R7—的两个相同或不同的第二残基结合。
• [EN] NANOPARTICLES FOR PHOTODYNAMIC THERAPY, X-RAY INDUCED PHOTODYNAMIC THERAPY, RADIOTHERAPY, CHEMOTHERAPY, IMMUNOTHERAPY, AND ANY COMBINATION THEREOF<br/>[FR] NANOPARTICULES POUR THÉRAPIE PHOTODYNAMIQUE, THÉRAPIE PHOTODYNAMIQUE INDUITE PAR RAYONS X, RADIOTHÉRAPIE, CHIMIOTHÉRAPIE, IMMUNOTHÉRAPIE, ET TOUTE COMBINAISON DE CELLES-CI
  申请人：UNIV CHICAGO

  公开号：WO2016061256A1

  公开（公告）日：2016-04-21

  Metal-organic frameworks (MOFs) comprising photosensitizers are described. The MOFs can also include moieties capable of absorbing X- rays and/or scintillation. Optionally, the photosensitizer or a derivative thereof can form a bridging ligand of the MOF. Further optionally, the MOF can comprise inorganic nanoparticles in the cavities or channels of the MOF or can be used in combination with an inorganic nanoparticle. Also described are methods of using MOFs and/or inorganic nanoparticles in photodynamic therapy or in X-ray induced photodynamic therapy, either with or without the co-administration of one or more immunotherapeutic agent and/or one or more chemotherapeutic agent.

  金属有机框架（MOFs）包括光敏剂。MOFs还可以包括能够吸收X射线和/或闪烁的基团。可选地，光敏剂或其衍生物可以形成MOF的桥联配体。进一步可选地，MOF可以包括在MOF的腔或通道中的无机纳米粒子，或者可以与无机纳米粒子结合使用。还描述了在光动力疗法或X射线诱导的光动力疗法中使用MOFs和/或无机纳米粒子的方法，无论是否与一个或多个免疫治疗剂和/或一个或多个化学治疗剂联合给药。
• Isoreticular metal-organic frameworks, process for forming the same, and systematic design of pore size and functionality therein, with application for gas storage
  申请人：——

  公开号：US20030004364A1

  公开（公告）日：2003-01-02

  The ability to design and construct solid-state materials with pre-determined structures is a grand challenge in chemistry. An inventive strategy based on reticulating metal ions and organic carboxylate links into extended networks has been advanced to a point that has allowed the design of porous structures in which pore size and functionality can be varied systematically. MOF-5, a prototype of a new class of porous materials and one that is constructed from octahedral Zn—O—C clusters and benzene links, was used to demonstrate that its 3-D porous system can be functionalized with the organic groups, —Br, —NH2, —OC 3 H 7 , —OC 5 H 11 , —H 4 C 2 , and —H 4 C 4 , and its pore size expanded with the long molecular struts biphenyl, tetrahydropyrene, pyrene, and terphenyl. The ability to direct the formation of the octahedral clusters in the presence of a desired carboxylate link is an essential feature of this strategy, which resulted in the design of an isoreticular (having the same framework topology) series of sixteen well-defined materials whose crystals have open space representing up to 91.1% of the crystal volume, and homogeneous periodic pores that can be incrementally varied from 3.8 to 28.8 angstroms. Unlike the unpredictable nature of zeolite and other molecular sieve syntheses, the deliberate control exercised at the molecular level in the design of these crystals is expected to have tremendous implications on materials properties and future technologies. Indeed, data indicate that members of this series represent the first monocrystalline mesoporous organic/inorganic frameworks, and exhibit the highest capacity for methane storage (155 cm 3 /cm 3 at 36 atm) and the lowest densities (0.41 to 0.21 g/cm 3 ) attained to date for any crystalline material at room temperature.

  在化学领域，设计和构建预定结构的固态材料是一个宏伟的挑战。一种基于将金属离子和有机羧酸连接成扩展网络的创新策略已经发展到了一定程度，使得可以设计出可系统变化孔径和功能的多孔结构。 MOF-5是一种新型多孔材料的原型，由八面体Zn-O-C簇和苯基连接构成，证明了其三维多孔系统可以通过有机基团（-Br，-NH2，-OC3H7，-OC5H11，-H4C2和-H4C4）进行功能化，并且可以使用长分子支架二苯基、四氢萘、芘和二联苯来扩展其孔径。在所需的羧酸连接物存在的情况下，指导八面体簇的形成是这种策略的一个重要特征，这导致设计出一个等网系列的十六种定义明确的材料，其晶体的开放空间占晶体体积的最高达91.1％，并且具有均匀的周期性孔隙，可以从3.8到28.8埃逐渐变化。与沸石和其他分子筛合成的不可预测性不同，这些晶体的设计在分子水平上有意控制，预计对材料性质和未来技术产生巨大影响。实际上，数据表明，该系列成员代表了第一批单晶介孔有机/无机框架，并且在室温下具有迄今为止任何晶体材料的最高甲烷存储容量（155 cm3/cm3，36 atm）和最低密度（0.41至0.21 g/cm3）。
• Polymeric liquid crystal composition and liquid crystal device
  申请人：CANON KABUSHIKI KAISHA

  公开号：EP0292244A2

  公开（公告）日：1988-11-23

  A polymeric liquid crystal composition comprises a polymer mesomorphic compound having an asymmetric carbon atom and a low-molecular weight mesomorphic compound. The composition can be easily formed into a film of a large area, shows a response speed which is not substantially different from that of the low-molecular weight mesomorphic compound alone and stably retains alignment resistant to pressure or heat impact. Such a good alignment is especially obtained when the polymeric liquid crystal composition is incorporated in a liquid crystal device by being disposed between a pair of substrates preferably having an alignment face provided with an orientation characteristic for aligning the molecular axis of the liquid crystal composition in one direction. It is suitable that the polymer mesomorphic compound is optically active and has a helical rotation direction opposite to that of the low-molecular weight mesomorphic compound.

  一种聚合物液晶组合物由一种具有不对称碳原子的聚合物介形化合物和一种低分子量介形化合物组成。这种组合物很容易形成大面积的薄膜，其响应速度与低分子量介形化合物本身的响应速度相差不大，并能在压力或热冲击下稳定地保持排列。特别是当聚合物液晶组合物被放置在一对基板之间，使其与液晶组合物的分子轴向一个方向对齐时，可以获得良好的对齐效果。聚合物介形化合物具有光学活性，其螺旋旋转方向与低分子量介形化合物的螺旋旋转方向相反，这一点是合适的。
• Display medium, display method and display apparatus
  申请人：CANON KABUSHIKI KAISHA

  公开号：EP0346911A1

  公开（公告）日：1989-12-20

  A display medium having a display face is composed of a plurality of display layers (D1,D2) laminated perpendicularly to the display face. Each display layer (D1,D2) comprises a polymer liquid crystal showing a mesomorphic temperature range between its glass transition temperature and the upper limit temperature of a liquid crystal phase used for display. The mesomorphic temperature ranges of the plurality of display layers (D1,D2) do not overlap each other. The optical densities of the display layers (D1,D2) are controlled independently from the other, and the gradation of each color can be also controlled, so that a full-color display can be realized.

  一种具有显示面的显示介质由垂直于显示面层叠的多个显示层（D1、D2）组成。每个显示层（D1,D2）由聚合物液晶组成，显示出介于其玻璃转化温度和用于显示的液晶相的上限温度之间的介态温度范围。多个显示层（D1、D2）的中间温度范围互不重叠。显示层（D1、D2）的光密度可独立控制，每种颜色的渐变也可控制，因此可实现全彩显示。