(1-octyl)-(-4-oxy-phenylene) carbonate

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (1-octyl)-(-4-oxy-phenylene) carbonate
• 英文别名: (4-Hydroxyphenyl) octyl carbonate
• 化学式: C₁₅H₂₂O₄
• 分子量: 266.337
• InChiKey: DNQDAULPUKCIIT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.1
• 重原子数：
  19
• 可旋转键数：
  10
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.53
• 拓扑面积：
  55.8
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  氯甲酸正辛酯 、 对苯二酚 在 吡啶 、 4-二甲氨基吡啶 作用下， 以 乙酸乙酯 为溶剂， 反应 24.0h， 以68%的产率得到(1-octyl)-(-4-oxy-phenylene) carbonate
  参考文献：
  名称：

  Skin-depigmenting prodrugs of hydroquinone

  摘要：

  Novel mono-1 and bis-carbonates 2, and mono-3 and bis-pivaloyloxymethyl ethers 4 (bis-POM-ethers) of hydroquinone (HQ) evaluated as skin-lightening agents, showed that: 1) they cause an initial depigmentation of the skin; 2) the depigmenting effect is not maintained over prolonged periods of time; and 3) prolonged use results in a shift of the chromatic locus, suggesting the formation of a new chemical product in the skin. HQ was a more potent depigmenting agent than any of the derivatives tested.

  DOI：

  10.1016/0223-5234(93)90008-3

文献信息

• Liquid crystalline carbonic acid ester and liquid crystal composition containing same
  申请人：Chisso Corporation

  公开号：EP0225728A2

  公开（公告）日：1987-06-16

  A ferroelectric liquid crystal compound having superior properties and a chiral smectic liquid crystal composition are provided, which ferroelectric liquid crystal is expressed by the formula wherein R represents an alkyl group of 2-18C; A, -COO- or -OCO-; ℓ and m each, 1 or 2 but f + m = 2 or 3; n, an integer of 2-8; and symbol *, an asymmetric carbon atom.

  本发明提供了一种具有优异性能的铁电液晶化合物和手性平滑液晶组合物，该铁电液晶由式表示，其中 R 代表 2-18C 的烷基；A，-COO- 或 -OCO-；ℓ 和 m 各为 1 或 2，但 f + m = 2 或 3；n，2-8 的整数；符号 *，不对称碳原子。
• US4759869A
  申请人：——

  公开号：US4759869A

  公开（公告）日：1988-07-26
• Skin-depigmenting prodrugs of hydroquinone
  作者：A Nudelman、Z Ben-Ishai、M Ruse、J Schamroth

  DOI：10.1016/0223-5234(93)90008-3

  日期：1993.1

  Novel mono-1 and bis-carbonates 2, and mono-3 and bis-pivaloyloxymethyl ethers 4 (bis-POM-ethers) of hydroquinone (HQ) evaluated as skin-lightening agents, showed that: 1) they cause an initial depigmentation of the skin; 2) the depigmenting effect is not maintained over prolonged periods of time; and 3) prolonged use results in a shift of the chromatic locus, suggesting the formation of a new chemical product in the skin. HQ was a more potent depigmenting agent than any of the derivatives tested.