N,N'-Diformyl-N,N'-diphenyl-2,3,5,6-tetrafluorophenylene-1,4-diamine

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N,N'-Diformyl-N,N'-diphenyl-2,3,5,6-tetrafluorophenylene-1,4-diamine
• 英文别名: N-phenyl-N-[2,3,5,6-tetrafluoro-4-(N-formylanilino)phenyl]formamide
• 化学式: C₂₀H₁₂F₄N₂O₂
• 分子量: 388.321
• InChiKey: OGUBYUMGLVMQBT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.2
• 重原子数：
  28
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  40.6
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  六氟苯 、 N-苯基甲酰胺 在 sodium hydride 作用下， 以20%的产率得到N,N'-Diphenyl-2,3,5,6-tetrafluorophenylene-1,4-diamine
  参考文献：
  名称：

  Disubstitution on hexafluorobenzene with formanilides

  摘要：

  Nucleophilic attack on hexafluorobenzene by sodium formanilides gave N,N'-diphenyl-2,3,5,6-tetrafluorophenylene-1,4-diamine as the main product at elevated temperature and N,N'-diformyl-N,N'-diphenyl-2,3,5,6-tetrafluorophenylene-1,4-diamine as the main compound at ambient temperature. Metallation of formanilide with lithium hydroxide instead of sodium hydride gave only 2,3,4,5,6-pentafluorodiphenylamine.

  DOI：

  10.1016/0022-1139(95)90107-s

文献信息

• Disubstitution on hexafluorobenzene with formanilides
  作者：R. Koppang

  DOI：10.1016/0022-1139(95)90107-s

  日期：1995.10

  Nucleophilic attack on hexafluorobenzene by sodium formanilides gave N,N'-diphenyl-2,3,5,6-tetrafluorophenylene-1,4-diamine as the main product at elevated temperature and N,N'-diformyl-N,N'-diphenyl-2,3,5,6-tetrafluorophenylene-1,4-diamine as the main compound at ambient temperature. Metallation of formanilide with lithium hydroxide instead of sodium hydride gave only 2,3,4,5,6-pentafluorodiphenylamine.