1,3,5-tris(4-methyethyllphenyl)benzene

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1,3,5-tris(4-methyethyllphenyl)benzene
• 英文别名: 1,3,5-tris(4-isopropylphenyl)benzene；1,3,5-tris-(4-isopropyl-phenyl)-benzene；1,3,5-Tris-(4-isopropyl-phenyl)-benzol；1,3,5-Tris(4-propan-2-ylphenyl)benzene
• 化学式: C₃₃H₃₆
• 分子量: 432.649
• InChiKey: VWZYHPJUHNDMIX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  10.2
• 重原子数：
  33
• 可旋转键数：
  6
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.27
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为产物：
  描述：

  4'-异丙基苯乙酮 在 trichloro(trifluoromethanesulfonato)titanium(IV) 作用下， 反应 10.0h， 以100%的产率得到1,3,5-tris(4-methyethyllphenyl)benzene
  参考文献：
  名称：

  TiCl₃(OTf) Catalyses the Efficient Conversion of Acetophenones to 1,3,5-Triaryl Benzenes

  摘要：

  不同取代乙酰苯在催化量的TiCl3(OTf)存在下，于密封管中90-100°C温度下，成功定量转化为相应的1,3,5-三取代苯。

  DOI：

  10.1055/s-1998-1875

文献信息

• Nano-silica sulfuric acid catalyzed the efficient synthesis of 1,3,5-triarylbenzenes under microwave irradiation
  作者：R. Ghanbaripour、I. Mohammadpoor-Baltork、M. Moghadam、A. R. Khosropour、S. Tangestaninejad、V. Mirkhani

  DOI：10.1007/s13738-012-0089-0

  日期：2012.10

  Nano-silica sulfuric acid as a heterogeneous, eco-friendly and reusable catalyst was used in the synthesis of 1,3,5-triarylbenzenes via triple-self condensation of acetophenones. All reactions were performed under solvent-free conditions and microwave irradiation. Short reaction times, high yields, easy isolation and purification of products and good reusability of this catalyst are the mainspring to choose for the preparation of 1,3,5-triarylbenzenes.

  纳米二氧化硅硫酸作为异相、环保且可重复使用的催化剂，被用于通过乙酰苯的三重自缩合反应合成1,3,5-三芳基苯。所有反应均在无溶剂条件和微波辐射下进行。短反应时间、高产率、产品易于分离和纯化以及该催化剂的良好重复性是制备1,3,5-三芳基苯选择这种催化剂的主要原因。
• Efficient Conversion of Acetophenones into 1,3,5-Triarylbenzenes Catalyzed by Bismuth(III) Trifluoromethanesulfonate Tetrahydrate
  作者：Tsuneo Sato、Fumiaki Ono、Yuichi Ishikura、Yuusuke Tada、Masato Endo

  DOI：10.1055/s-2008-1078012

  日期：——

  Bismuth(III) trifluoromethanesulfonate tetrahydrate is found to efficiently catalyze the cyclotrimerization of acetophenones into 1,3,5-triarylbenzenes in good yields.

  三氟甲磺酸铋(III)四水合物被发现能高效催化苯乙酮的环三聚反应，生成高产率的1,3,5-三芳基苯。
• TiCl₃(OTf) Catalyses the Efficient Conversion of Acetophenones to 1,3,5-Triaryl Benzenes
  作者：N. Iranpoor、B. Zeynizaded

  DOI：10.1055/s-1998-1875

  日期：1998.10

  The quantitative conversion of different substituted acetophenones to their corresponding 1,3,5-triaryl benzenes was achieved in the presence of catalytic amounts of TiCl3(OTf) in sealed tubes at 90-100 °C.

  不同取代乙酰苯在催化量的TiCl3(OTf)存在下，于密封管中90-100°C温度下，成功定量转化为相应的1,3,5-三取代苯。
• A Facile Synthesis of 1,3,5-Triaryl Benzenes from Acetophenone Diethyl Ketals in the Presence of Acetyl Chloride and SmCl₃
  作者：Ke-Jun Cheng、Zong-Biao Ding、Shi-Hui Wu

  DOI：10.1080/00397919708004800

  日期：1997.1.1

  Abstract Samarium trichloride, SmCl3, has been found to be an efficient catalyst for the synthesis of 1,3,5-triaryl benzenes from acetophenone diethyl ketals in the presence of acetyl chloride under solvent of pentane and mild conditions.

  摘要 三氯化钐 SmCl3 已被发现是在戊烷溶剂和温和条件下，在乙酰氯存在下，由苯乙酮二乙基缩酮合成 1,3,5-三芳基苯的有效催化剂。
• Microwave-promoted efficient conversion of acetophenones to 1,3,5-triarylbenzenes catalyzed by H3PW12O40 and nano-silica supported H3PW12O40 as reusable catalysts
  作者：Rashid Ghanbaripour、Iraj Mohammadpoor-Baltork、Majid Moghadam、Ahmad R. Khosropour、Shahram Tangestaninejad、Valiollah Mirkhani

  DOI：10.1016/j.poly.2011.10.027

  日期：2012.1

  H3PW12O40 and nano-silica supported H3PW12O40 were found to be efficient heterogeneous catalysts for the preparation of 1,3,5-triarylbenzenes via triple self condensation of acetophenones under microwave irradiation and solvent-free conditions. High yields, short reaction times, easy work-up, easy availability and handling, eco-friendly and reusability of the catalysts are the main aspects of the present method. The catalytic mechanism of 1,3,5-triarylbenzenes synthesis is also proposed. (C) 2011 Elsevier Ltd. All rights reserved.