四(2-羟基乙基)溴化铵 | 4328-04-5

• 物质功能分类: 化学试剂 - 有机试剂 - 胺盐（铵盐）
• 分子结构分类: 有机化合物 - 有机氮化合物
• 中文名称: 四(2-羟基乙基)溴化铵
• 英文名称: tetrakis(2-hydroxyethyl)ammonium bromide
• 英文别名: tetrakis(2-hydroxyethyl)azanium;bromide
• CAS: 4328-04-5
• 化学式: Br*C₈H₂₀NO₄
• 分子量: 274.155
• InChiKey: HAKHOKJQPCRWAS-UHFFFAOYSA-M

物化性质

• 熔点：
  191 °C
• 密度：
  1.5267 (rough estimate)
• 稳定性/保质期：
  在常温常压下保持稳定，应避免与不相容的材料接触，并注意不要与强氧化剂发生反应。

计算性质

• 辛醇/水分配系数(LogP)：
  -5.22
• 重原子数：
  14
• 可旋转键数：
  8
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  80.9
• 氢给体数：
  4
• 氢受体数：
  5

安全信息

• 安全说明：
  S24/25
• 海关编码：
  2923900090
• 储存条件：
  密封保存，应储存在阴凉干燥的仓库中。

SDS

Name:	Tetrakis(2-Hydroxyethyl)Ammonium Bromide 99% (Titr.) Material Safety Data Sheet
Synonym:	Ethanaminium,2-Hydroxy-N,N,N-Tris(2-Hydroxyethyl)-, Bromide
CAS:	4328-04-5

Section 1 - Chemical Product MSDS Name:Tetrakis(2-Hydroxyethyl)Ammonium Bromide 99% (Titr.) Material Safety Data Sheet
Synonym:Ethanaminium,2-Hydroxy-N,N,N-Tris(2-Hydroxyethyl)-, Bromide

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Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS

CAS#	Chemical Name	content	EINECS#
4328-04-5	Tetrakis(2-Hydroxyethyl)Ammonium Bromi	99%	224-362-6

Hazard Symbols: None Listed.
Risk Phrases: None Listed.

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Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
The toxicological properties of this material have not been fully investigated.
Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause skin irritation.
Ingestion:
May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated.
Inhalation:
May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.
Chronic:
No information found.

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Section 4 - FIRST AID MEASURES
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Ingestion:
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:

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Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Runoff from fire control or dilution water may cause pollution.
Extinguishing Media:
Use agent most appropriate to extinguish fire. Use water spray, dry chemical, carbon dioxide, or appropriate foam.

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Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, observing precautions in the Protective Equipment section. Avoid generating dusty conditions.
Provide ventilation.

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Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.
Storage:
Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

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Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use process enclosure, local exhaust ventilation, or other engineering controls to control airborne levels.
Exposure Limits CAS# 4328-04-5: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to minimize contact with skin.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

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Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Crystalline powder
Color: almost white
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 191 deg C
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density:
Molecular Formula: C8H20BrNO4
Molecular Weight: 274.15

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Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Incompatible materials, dust generation, excess heat, strong oxidants.
Incompatibilities with Other Materials:
Oxidizing agents.
Hazardous Decomposition Products:
Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, hydrogen bromide.
Hazardous Polymerization: Has not been reported

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Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 4328-04-5 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
Tetrakis(2-Hydroxyethyl)Ammonium Bromide - Not listed by ACGIH, IARC, or NTP.

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Section 12 - ECOLOGICAL INFORMATION

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Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.

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Section 14 - TRANSPORT INFORMATION

IATA
Not regulated as a hazardous material.
IMO
Not regulated as a hazardous material.
RID/ADR
Not regulated as a hazardous material.

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Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: Not available.
Risk Phrases:
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
WGK (Water Danger/Protection)
CAS# 4328-04-5: No information available.
Canada
CAS# 4328-04-5 is listed on Canada's NDSL List.
CAS# 4328-04-5 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 4328-04-5 is listed on the TSCA inventory.

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SECTION 16 - ADDITIONAL INFORMATION
N/A

反应信息

• 作为反应物：
  描述：

  四(2-羟基乙基)溴化铵 在 氢溴酸 作用下， 生成 4,4-bis-(2-bromo-ethyl)-morpholinium; bromide
  参考文献：
  名称：

  Prelog; Blazek, Collection of Czechoslovak Chemical Communications, 1934, vol. 6, p. 484

  摘要：

  DOI：
• 作为产物：
  描述：

  2-溴乙醇 在 三乙醇胺 作用下， 生成 四(2-羟基乙基)溴化铵
  参考文献：
  名称：

  New water-soluble salts of cannabinoids, preparation and uses thereof

  摘要：

  新型水溶性大麻素盐，其生物利用度增加，其制备和用途。

  公开号：

  US20220332694A1

文献信息

• Effect of hydrogen bond of hydroxyl-functionalized ammonium ionic liquids on cycloaddition of CO2
  作者：Weiguo Cheng、Benneng Xiao、Jian Sun、Kun Dong、Peng Zhang、Suojiang Zhang、Flora T.T. Ng

  DOI：10.1016/j.tetlet.2015.01.174

  日期：2015.3

  synergistic effect of the hydrogen bond on the cycloaddition of CO2 and epoxides to form cyclic carbonates was investigated through experimental study and characterization. A highly effective homogeneous system of hydroxyl-functionalized quaternary ammonium ionic liquids with a different number of the hydroxyl group in the cation was developed for the fixation of CO2 to form cyclic carbonates. A mechanism via

  通过实验研究和表征，研究了氢键对CO 2和环氧化物形成环碳酸酯的环加成的协同作用。为了固定CO 2形成环状碳酸酯，开发了一种高效的均相体系，该体系由阳离子中具有不同羟基数的羟基官能化季铵离子液体组成。根据实验数据和模型，提出了通过氢键活化进行环加成反应的机理。这项研究增进了对通过氢键促进反应的理解，并为合理设计将CO 2固定为有机化合物的催化体系奠定了基础。
• ORGANIC ELECTROLYTE COMPOUNDS FOR REDOX-FLOW BATTERIES
  申请人：FUNDACIÓN CENTRO DE INVESTIGACIÓN COOPERATIVA DE ENERGÍAS ALTERNATIVAS CIC ENERGIGUNE FUNDAZIOA

  公开号：US20180079721A1

  公开（公告）日：2018-03-22

  The present invention relates to redox electrolyte compounds. The present invention further relates to a redox-flow battery wherein one of the catholyte and the anolyte, or both, has the redox electrolyte compound of the invention. The present invention further relates to the method of controlling the redox-flow battery and its use for energy storage.

  本发明涉及氧化还原电解质化合物。本发明还涉及一种氧化还原流电池，其中阴极液和/或阳极液中至少一种含有本发明的氧化还原电解质化合物。本发明还涉及控制氧化还原流电池的方法及其用于储能的用途。
• 对苯二甲酸酯季铵盐及其制备方法、用途
  申请人：怀化学院

  公开号：CN109369536A

  公开（公告）日：2019-02-22

  本发明涉及一种对苯二甲酸酯季铵盐及其制备方法、用途，该对苯二甲酸酯季铵盐将具有羟乙基的季铵盐与苯二甲酰氯发生缩合反应制得。上述对苯二甲酸酯季铵盐的制备方法，制备方法简单，制得的对苯二甲酸酯季铵盐具有一定的离子电导性，可用作有机电解质及聚合物成核剂。
• New cardiolipin analogs synthesized by phospholipase D-catalyzed transphosphatidylation
  作者：Anna O. Müller、Carmen Mrestani-Klaus、Jürgen Schmidt、Renate Ulbrich-Hofmann、Martin Dippe

  DOI：10.1016/j.chemphyslip.2012.09.005

  日期：2012.10

  with bulky nitrogenous acceptor alcohols (triethanolamine, tris(hydroxymethyl)aminomethane, tetrakis(hydroxyethyl)ammonium) or the non-charged alcohols. Therefore, a strong dependence of the conversion of the monophosphatidyl to the diphosphatidyl compound on steric parameters and the head group charge was concluded. The enzyme-assisted strategy was used for the preparation of purified diphosphatidyldiethanolamine

  由于其化学合成的复杂性，很难获得心磷脂（CL）和相关的二磷脂酰脂质。本文研究了链霉菌中磷脂酶D（PLD）的催化转磷酸化反应。sp。已被证明是合成新的CL类似物的另一种酶辅助策略。比较了由磷脂酰胆碱形成的这类化合物与一系列N-和C2-取代的乙醇胺衍生物以及不带电荷的醇（如甘油和乙二醇）的形成。具有低分子体积的乙醇胺衍生物（二乙醇胺和丝氨醇）可快速交换胆碱首基，可有效生产相应的CL类似物。相反，与大量的含氮受体醇（三乙醇胺，三（羟甲基）氨基甲烷，四（羟乙基）铵）或不带电荷的醇反应时，收率相对较低。所以，结论是，单磷脂酰向二磷脂酰化合物的转化对空间参数和头基电荷的强烈依赖性。酶辅助策略用于制备纯化的二磷脂酰二乙醇胺和二磷脂酰丝氨醇。
• Organic electrolyte compounds for redox-flow batteries
  申请人：FUNDACIÓN CENTRO DE INVESTIGACIÓN COOPERATIVA DE ENERGÍAS ALTERNATIVAS CIC ENERGIGUNE FUNDAZIOA

  公开号：US10710964B2

  公开（公告）日：2020-07-14

  The present invention relates to redox electrolyte compounds. The present invention further relates to a redox-flow battery wherein one of the catholyte and the anolyte, or both, has the redox electrolyte compound of the invention. The present invention further relates to the method of controlling the redox-flow battery and its use for energy storage.

  本发明涉及氧化还原电解质化合物。本发明进一步涉及一种氧化还原液流电池，其中阴离子溶液和阳离子溶液之一或两者都具有本发明的氧化还原电解质化合物。本发明还涉及氧化还原液流电池的控制方法及其储能用途。