1-((4-isopropylphenyl)thio)-2-methylpropan-2-ol

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1-((4-isopropylphenyl)thio)-2-methylpropan-2-ol
• 化学式: C₁₃H₂₀OS
• 分子量: 224.367
• InChiKey: VEIJEWUECSWQOG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.67
• 重原子数：
  15.0
• 可旋转键数：
  4.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.54
• 拓扑面积：
  20.23
• 氢给体数：
  1.0
• 氢受体数：
  2.0

反应信息

• 作为产物：
  描述：

  甲基环氧丙烷 、 对异丙基苯硫酚 在 BiCl₆^(3-)*2C₄H₁₀N₂*ClH*3H⁽¹⁺⁾*H₂O 作用下， 以 neat (no solvent) 为溶剂， 反应 0.17h， 以76%的产率得到1-((4-isopropylphenyl)thio)-2-methylpropan-2-ol
  参考文献：
  名称：

  An efficient catalyst for ring opening of epoxides with phenol and thiophenol under solvent-free conditions

  摘要：

  An efficient and rapid procedure for ring opening reaction of various epoxides with phenol and thiophenol derivatives was developed. The procedure can be obtained at room temperature under solvent-free condition in presence of (C4H12N2)(2)[Bicl(6)]Cl center dot H2O (1 mol %). This catalyst can be reused several times without significant loss of activity. (C) 2013 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2013.10.098

文献信息

• An efficient catalyst for ring opening of epoxides with phenol and thiophenol under solvent-free conditions
  作者：Hong-fei Lu、Jun-tao Zhou、He-long Cheng、Lei-lei Sun、Fei-fei Yang、Run-ze Wu、Yu-hua Gao、Zhi-bin Luo

  DOI：10.1016/j.tet.2013.10.098

  日期：2013.12

  An efficient and rapid procedure for ring opening reaction of various epoxides with phenol and thiophenol derivatives was developed. The procedure can be obtained at room temperature under solvent-free condition in presence of (C4H12N2)(2)[Bicl(6)]Cl center dot H2O (1 mol %). This catalyst can be reused several times without significant loss of activity. (C) 2013 Elsevier Ltd. All rights reserved.