2-diphenylphosphinyl-1-(4-tolyl)-1-(6-oxido-6H-dibenz[c,e][1,2]oxaphosphorin-6-yl)ethane

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-diphenylphosphinyl-1-(4-tolyl)-1-(6-oxido-6H-dibenz[c,e][1,2]oxaphosphorin-6-yl)ethane
• 英文别名: 6-[2-Diphenylphosphoryl-1-(4-methylphenyl)ethyl]benzo[c][2,1]benzoxaphosphinine 6-oxide；6-[2-diphenylphosphoryl-1-(4-methylphenyl)ethyl]benzo[c][2,1]benzoxaphosphinine 6-oxide
• 化学式: C₃₃H₂₈O₃P₂
• 分子量: 534.531
• InChiKey: NCIDYVVCAVWIQM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.7
• 重原子数：
  38
• 可旋转键数：
  6
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.09
• 拓扑面积：
  43.4
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  (E)-(4-methylstyryl)diphenylphosphine oxide 、 9,10-二氢-9-氧杂-10-磷杂菲-10-氧化物 以71%的产率得到2-diphenylphosphinyl-1-(4-tolyl)-1-(6-oxido-6H-dibenz[c,e][1,2]oxaphosphorin-6-yl)ethane
  参考文献：
  名称：

  Microwave-Assisted Regioselective Addition of P(O)−H Bonds to Alkenes without Added Solvent or Catalyst

  摘要：

  The addition of P(O)-H bonds to alkenes has been accomplished using microwave irradiation in the absence of added solvent and catalyst. In addition to single addition reactions, tandem hydrophosphinylation reactions with alkynes afforded unsymmetrical species such as phosphine oxide - phosphinates.

  DOI：

  10.1021/ol0474047

文献信息

• Microwave-Assisted Regioselective Addition of P(O)−H Bonds to Alkenes without Added Solvent or Catalyst
  作者：Robert A. Stockland,、Ross I. Taylor、Laura E. Thompson、Priti B. Patel

  DOI：10.1021/ol0474047

  日期：2005.3.1

  The addition of P(O)-H bonds to alkenes has been accomplished using microwave irradiation in the absence of added solvent and catalyst. In addition to single addition reactions, tandem hydrophosphinylation reactions with alkynes afforded unsymmetrical species such as phosphine oxide - phosphinates.