butyl(4-hydroxyphenyl)tellane

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: butyl(4-hydroxyphenyl)tellane
• 英文别名: 4-Butyltellanylphenol
• 化学式: C₁₀H₁₄OTe
• 分子量: 277.821
• InChiKey: FEQAKHUDHWIVRH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.94
• 重原子数：
  12
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  butyl(4-hydroxyphenyl)tellane 、 苯基三氟硼酸钾 在 四(三苯基膦)钯 、 三乙胺 、 silver(l) oxide 作用下， 以 甲醇 为溶剂， 反应 1.5h， 以92%的产率得到对羟基联苯
  参考文献：
  名称：

  Suzuki−Miyaura Cross-Coupling Reactions of Aryl Tellurides with Potassium Aryltrifluoroborate Salts

  摘要：

  Palladium(O)-catalyzed cross-coupling between potassium aryltrifluoroborate salts and aryl tellurides proceeds readily to afford the desired biaryls in good to excellent yield. The reaction seems to be unaffected by the presence of electron-withdrawing or electron-donating substituents in both the potassium aryltrifluoroborate salts and aryl tellurides partners. Biaryls containing a variety of functional groups can be prepared. A chemoselectivity study was also carried out using aryl tellurides bearing halogen atoms in the same compound. In addition, this new version of the Suzuki-Miyaura cross-coupling reaction was monitored by electrospray ionization mass spectrometry where some reaction intermediates were detected and analyzed.

  DOI：

  10.1021/jo052061r
• 作为产物：
  描述：

  正溴丁烷 、 4-hydroxyphenyltellurium trichloride 在 sodium tetrahydroborate 作用下， 以 四氢呋喃 为溶剂， 反应 0.33h， 以70%的产率得到butyl(4-hydroxyphenyl)tellane
  参考文献：
  名称：

  Suzuki−Miyaura Cross-Coupling Reactions of Aryl Tellurides with Potassium Aryltrifluoroborate Salts

  摘要：

  Palladium(O)-catalyzed cross-coupling between potassium aryltrifluoroborate salts and aryl tellurides proceeds readily to afford the desired biaryls in good to excellent yield. The reaction seems to be unaffected by the presence of electron-withdrawing or electron-donating substituents in both the potassium aryltrifluoroborate salts and aryl tellurides partners. Biaryls containing a variety of functional groups can be prepared. A chemoselectivity study was also carried out using aryl tellurides bearing halogen atoms in the same compound. In addition, this new version of the Suzuki-Miyaura cross-coupling reaction was monitored by electrospray ionization mass spectrometry where some reaction intermediates were detected and analyzed.

  DOI：

  10.1021/jo052061r

文献信息

• Synthesis of benzophenones from geminal biaryl ethenes using m-chloroperbenzoic acid
  作者：Fateh V. Singh、Humberto M.S. Milagre、Marcos N. Eberlin、Helio A. Stefani

  DOI：10.1016/j.tetlet.2009.02.164

  日期：2009.5

  The oxidation of geminal biaryl ethenes 3 and 1,3-enynes 5 using m-chloroperbenzoic acid in dichloromethane at room temperature presents a catalyst-free approach for the synthesis of functionalized benzophenones 4 and ynones 6, respectively. (C) 2009 Elsevier Ltd. All rights reserved.