2-(hydroxymethyl)phenyl formate

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-(hydroxymethyl)phenyl formate
• 英文别名: [2-(hydroxymethyl)phenyl] formate
• 化学式: C₈H₈O₃
• 分子量: 152.15
• InChiKey: UAOGUDWFQMASCC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.9
• 重原子数：
  11
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  46.5
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  水杨醇 、 N,N-二甲基甲酰胺 在 草酰氯 作用下， 以 二氯甲烷 为溶剂， 反应 6.0h， 以40%的产率得到2-(hydroxymethyl)phenyl formate
  参考文献：
  名称：

  了解 N,N-二甲基甲酰胺和草酰氯组合作为化学选择性 O-甲酰化剂的功效：统一的实验和理论研究

  摘要：

  摘要 我们开发了一种简单但有效的合成方案，用于在二氯甲烷 (DCM) 中使用 N,N-二甲基甲酰胺 (DMF) 和草酰氯 [(COCl)2] 组合对各种芳香羟基/酚类底物进行 O-甲酰化在环境温度下作为溶剂。发现 DMF/(COCl)2 组合对芳香族/酚羟基的化学选择性高于脂肪族羟基或芳香胺/硫醇基团。基于实验和基于密度泛函理论的理论研究结果解释了 DMF/(COCl)2 组合对芳香醇 O-甲酰化的这种化学选择性。图形概要

  DOI：

  10.1080/00397911.2016.1168450

文献信息

• Polyacene Compound And Organic Semiconductor Thin Film
  申请人：Nagata Kazuto

  公开号：US20080061287A1

  公开（公告）日：2008-03-13

  The present invention provides an organic semiconductor material which exhibits a high mobility, and excellent solubility in solvents and oxidation resistance. The present invention also provides an organic semiconductor thin film exhibiting a high mobility, and an organic semiconductor device exhibiting excellent electronic characteristics. A transistor structure is formed by coating the silicon substrate with a thin film of pentacene compound substituted halogens at 6 and 13 positions and aliphatic hydrocarbons at 2, 3, 9 and 10 positions, wherein the substrate is patterned beforehand with gold to have a source and drain electrodes.

  本发明提供了一种有机半导体材料，具有高迁移率、良好的溶解性和抗氧化性。本发明还提供了一种具有高迁移率的有机半导体薄膜和具有优异电子特性的有机半导体器件。晶体管结构通过在硅基底上涂覆取代卤素的五环芘化合物薄膜，在2、3、9和10位置涂覆脂肪族烃，其中底板事先用金图案制成源和漏极电极。
• Immunoassay method
  申请人：Ohzeki Katsuhisa

  公开号：US20080145869A1

  公开（公告）日：2008-06-19

  The present invention provides a method for immunoassaying an object to be analyzed including: causing to act, on a specimen or a sample including the specimen, a first protein (Y), which can specifically recognize the object to be analyzed in the specimen and is modified by a labeling substance, so as to form a complex including the object to be analyzed and Y; and measuring the labeling substance contained in the complex or the labeling substance contained in the free protein (Y), wherein the measurement of the labeling substance is performed by a chemiluminescent method which includes sensing the light generated by chemiluminescence using a photothermographic material including at least an organic silver salt, a reducing agent for silver ions and a photosensitive silver halide to form a latent image, and making the latent image visible by thermal development. An easy, quick, and highly precise immunoassay method is provided.

  本发明提供了一种免疫分析待分析物的方法，包括：在含有待分析物的样本或标本上作用第一蛋白（Y），该蛋白可以特异性地识别标本中的待分析物并被标记物质改性，以形成包括待分析物和Y的复合物；并测量复合物中包含的标记物质或自由蛋白（Y）中包含的标记物质。其中，标记物质的测量是通过化学发光法进行的，该法包括使用至少含有有机银盐、银离子还原剂和感光银卤化物的光热材料来感应化学发光所产生的光，并通过热发展使潜像可见。提供了一种简单、快速、高精度的免疫分析方法。
• POLYACENE COMPOUND AND ORGANIC SEMICONDUCTOR THIN FILM
  申请人：NAGATA Kazuto

  公开号：US20120108850A1

  公开（公告）日：2012-05-03

  The present invention provides an organic semiconductor material which exhibits a high mobility, and excellent solubility in solvents and oxidation resistance. The present invention also provides an organic semiconductor thin film exhibiting a high mobility, and an organic semiconductor device exhibiting excellent electronic characteristics. A transistor structure is formed by coating the silicon substrate with a thin film of pentacene compound substituted halogens at 6 and 13 positions and aliphatic hydrocarbons at 2, 3, 9 and 10 positions, wherein the substrate is patterned beforehand with gold to have a source and drain electrodes.

  本发明提供了一种有机半导体材料，具有高迁移率、良好的溶解性和氧化抗性。本发明还提供了一种具有高迁移率的有机半导体薄膜和具有优异电子特性的有机半导体器件。通过在硅衬底上涂覆取代卤素的五环芘化合物薄膜和2、3、9和10位脂肪族烃的薄膜，形成晶体管结构，其中衬底预先用金进行图案处理以具有源和漏极电极。
• Phenolic resins
  申请人：BORDEN (UK) LIMITED

  公开号：EP0377996A1

  公开（公告）日：1990-07-18

  A cured phenolic resin may be prepared by reacting (1) an esterified phenolic compound containing one or more phenolic hydroxyl groups and/or one or more esterified phenolic hydroxyl groups and further containing one or more esterified methylol groups positioned ortho and/or para to a phenolic hydroxyl group or esterified phenolic hydroxyl group with (2) a phenolic novolak resin in the presence of a base and water or other polar solvent. The invention is particularly useful for the production of foundry moulds or cores wherein the above composition is used as a binder for a granular refractory material such as sand.

  固化酚醛树脂的制备方法是：(1)含有一个或多个酚羟基和/或一个或多个酯化酚羟基并进一步含有一个或多个与酚羟基或酯化酚羟基正交和/或对位的酯化甲醇基的酯化酚化合物与(2)酚醛新戊二烯树脂在碱和水或其他极性溶剂存在下反应。本发明特别适用于生产铸造模具或芯模，其中上述组合物用作砂等颗粒状耐火材料的粘结剂。
• Color developing agent, silver halide photographic light-sensitive material and image forming method
  申请人：FUJI PHOTO FILM CO., LTD.

  公开号：EP0727708A1

  公开（公告）日：1996-08-21

  There is disclosed a light-sensitive material comprising, in a hydrophilic colloid provided on a base, a color-developing agent represented by formula (I) or (II):         R3-NHNH-Z2     formula (II)    wherein Z1 represents an acyl group, a carbamoyl group, an alkoxycarbonyl group, or an aryloxycarbonyl group; Z2 represents a carbamoyl group, an alkoxycarbonyl group, or an aryloxycarbonyl group; X1, X2, X3, X4, and X5 each represent a hydrogen atom or a substituent, provided that the sum of the Hammett substituent constant σp values of X1, X3, and X5 and the Hammett substituent constant σm values of X2 and X4 is 0.80 or more but 3.80 or below; and R3 represents a heterocyclic group. There is also disclosed a novel color-developing agent that can be built in. By using the color-developing agent, the light-sensitive material can attain a rapid and simple formation of an image.

  本发明公开了一种光敏材料，它包含在基底上的亲水性胶体中，由式 (I) 或 (II) 所代表的显色剂： R3-NHNH-Z2 式(II) 其中 Z1 代表酰基、氨基甲酰基、烷氧羰基或芳氧羰基；Z2 代表氨基甲酰基、烷氧羰基或芳氧羰基；X1、X2、X3、X4 和 X5 各自代表氢原子或取代基，条件是 X1、X3 和 X5 的哈米特取代基常数 σp 值与 X2 和 X4 的哈米特取代基常数 σm 值之和为 0.80或以上，但为3.80或以下；R3代表杂环基团。还公开了一种可内置的新型显色剂。通过使用该显色剂，感光材料可以快速简单地形成图像。