n-octyl((Z)-1-phenyl-2-cyanoethenyl)phosphine

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: n-octyl((Z)-1-phenyl-2-cyanoethenyl)phosphine
• 英文别名: (Z)-3-octylphosphanyl-3-phenylprop-2-enenitrile
• 化学式: C₁₇H₂₄NP
• 分子量: 273.358
• InChiKey: NUMLAUOYGMKVRX-LGMDPLHJSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.8
• 重原子数：
  19
• 可旋转键数：
  9
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.47
• 拓扑面积：
  23.8
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  octylphosphine 、 3-苯基丙炔腈 在 氢氧化钾 作用下， 以 1,4-二氧六环 、 水 为溶剂， 以70%的产率得到n-octyl((Z)-1-phenyl-2-cyanoethenyl)phosphine
  参考文献：
  名称：

  Regio- and stereospecific addition of phosphines to cyanoacetylenes

  摘要：

  Primary and secondary phosphines add regio- and stereospecifically to phenylcyanoacetylene and 4-hydroxy-4-methylpent-2-ynenitrile under mild conditions to form corresponding functionalized secondary and tertiary phosphines of Z-configuration in 70-91% yield. According to ESR and UV data, the addition of primary phosphines to phenylcyanoacetylene involves a single electron transfer process. (C) 2003 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4020(03)00694-x

文献信息

• Regio- and stereospecific addition of phosphines to cyanoacetylenes
  作者：Nina K Gusarova、Svetlana I Shaikhudinova、Svetlana N Arbuzova、Tamara I Vakul'skaya、Boris G Sukhov、Lidiya M Sinegovskaya、Mikhail V Nikitin、Anastasiya G Mal'kina、Nataliya A Chernysheva、Boris A Trofimov

  DOI：10.1016/s0040-4020(03)00694-x

  日期：2003.6

  Primary and secondary phosphines add regio- and stereospecifically to phenylcyanoacetylene and 4-hydroxy-4-methylpent-2-ynenitrile under mild conditions to form corresponding functionalized secondary and tertiary phosphines of Z-configuration in 70-91% yield. According to ESR and UV data, the addition of primary phosphines to phenylcyanoacetylene involves a single electron transfer process. (C) 2003 Elsevier Science Ltd. All rights reserved.