1,1,1-trifluoro-3-<2-(5-methylpyridyl)>-2-propanone

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 1,1,1-trifluoro-3-<2-(5-methylpyridyl)>-2-propanone
• 英文别名: 1,1,1-Trifluoro-3-(5-methylpyridin-2-yl)propan-2-one
• 化学式: C₉H₈F₃NO
• 分子量: 203.164
• InChiKey: UZEJNRGOWDWBBN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  14
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  30
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  2,5-二甲基吡啶 、 三氟乙酸酐 在 吡啶 作用下， 以 苯 为溶剂， 反应 24.0h， 以56%的产率得到1,1,1-trifluoro-3-<2-(5-methylpyridyl)>-2-propanone
  参考文献：
  名称：

  Trifluoroacetylation of Methylpyridines and Other Methylazines: A Convenient Access to Trifluoroacetonylazines

  摘要：

  Treatment of methyl substituted azines, such as pyridine, pyrimidine, quinoline, oxazole, benzoxazole, benzimidazole, and benzothiazole, with trifluoroacetic anhydride in the presence of pyridine at room temperature gave the corresponding trifluoroacetonyl substituted azines in good yields.

  DOI：

  10.3987/com-98-8268

文献信息

• DISPERSION OF WATER-INSOLUBLE COLORANT, METHOD OF PRODUCING SUBSTANCE CONTAINING WATER-INSOLUBLE COLORANT, FINE PARTICLES OF WATER-INSOLUBLE COLORANT, DISPERSING AGENT FOR WATER-INSOLUBLE COLORANT, AND RECORDING LIQUID, INK SET, PRINTED ARTICLE, METHOD OF FORMING IMAGE AND IMAGE FORMING APPARATUS USING THE SAME
  申请人：SANO Satoshi

  公开号：US20090246481A1

  公开（公告）日：2009-10-01

  A dispersion of a water-insoluble colorant containing: a medium containing water; fine particles of the water-insoluble colorant; and a polymer compound or a surfactant that includes at least one kind of electron-withdrawing group or group of atoms represented by any one of formulae (I) to (IV) as its hydrophilic part: wherein at least one of X 1 and X 2 represents an electron-withdrawing linking group on the condition that when at least one of X 1 and X 2 is not the linking group, the at least one of X 1 and X 2 represents an electron-withdrawing substituent; R 1 represents a hydrogen atom or a substituent; and M represents a hydrogen atom or a metal atom.

  一种水不溶性着色剂的分散体，包括：含水介质；水不溶性着色剂的细小颗粒；以及聚合物化合物或表面活性剂，其包含至少一种电子吸引基团或由式（I）至（IV）中的任何一种原子团表示的原子团作为其亲水部分：其中X1和X2中至少一个表示电子吸引连接基团，条件是当X1和X2中至少一个不是连接基团时，X1和X2中的至少一个表示电子吸引取代基；R1表示氢原子或取代基；M表示氢原子或金属原子。
• Trifluoroacetylation of Methylpyridines and Other Methylazines: A Convenient Access to Trifluoroacetonylazines
  作者：Masami Kawase、Mutsumi Teshima、Setsuo Saito、Satoru Tani

  DOI：10.3987/com-98-8268

  日期：——

  Treatment of methyl substituted azines, such as pyridine, pyrimidine, quinoline, oxazole, benzoxazole, benzimidazole, and benzothiazole, with trifluoroacetic anhydride in the presence of pyridine at room temperature gave the corresponding trifluoroacetonyl substituted azines in good yields.