奈福泮N-氧化物 | 66091-32-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 奈福泮N-氧化物
• 英文名称: Nefopam N-Oxide
• 英文别名: 5-methyl-5-oxido-1-phenyl-1,3,4,6-tetrahydro-2,5-benzoxazocin-5-ium
• CAS: 66091-32-5
• 化学式: C17H19NO2
• 分子量: 269.34
• InChiKey: ADOSMCNCNFMWSW-UHFFFAOYSA-N

物化性质

• 溶解度：
  可溶于氯仿（少许）、甲醇（少许）

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  20
• 可旋转键数：
  1
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  27.3
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• Synergistic combination of analgesic compounds
  申请人：GIRARD Philippe

  公开号：US20100197777A1

  公开（公告）日：2010-08-05

  The present invention relates to a pharmaceutical composition comprising as active substances: at least one compound of the following general formula (I): and at least one compound of the following general formula (V): especially for its use in the prevention or treatment of pain.
• Synergistic Combination of Analgesic Compounds
  申请人：GIRARD Philippe

  公开号：US20110136885A1

  公开（公告）日：2011-06-09

  The present invention relates to a pharmaceutical composition comprising as active substances: at least one compound of the following general formula (I): and at least one inhibitor of type 2 cyclooxygenase (COX-2), notably for use in the prevention or treatment of pain.
• US8575211B2
  申请人：——

  公开号：US8575211B2

  公开（公告）日：2013-11-05