毒理性
◉ 母乳喂养期间使用概述:外用氧康唑在哺乳期间尚未进行研究。由于局部应用后吸收少于1%,被认为对哺乳婴儿的风险较低。[1] 避免涂抹在乳头区域,并确保婴儿的皮肤不直接接触到已经涂抹药物的皮肤区域。只有水溶性的乳膏或凝胶产品可以涂抹在乳房上,因为药膏可能会使婴儿通过舔食接触到高水平的矿物石蜡。[2]
◉ 对哺乳婴儿的影响:截至修订日期,未找到相关的已发布信息。
◉ 对泌乳和母乳的影响:截至修订日期,未找到相关的已发布信息。
◉ Summary of Use during Lactation:Topical oxiconazole has not been studied during breastfeeding. Because less than 1% is absorbed after topical application, it is considered a low risk to the nursing infant.[1] Avoid application to the nipple area and ensure that the infant's skin does not come into direct contact with the areas of skin that have been treated. Only water-miscible cream or gel products should be applied to the breast because ointments may expose the infant to high levels of mineral paraffins via licking.[2]
◉ Effects in Breastfed Infants:Relevant published information was not found as of the revision date.
◉ Effects on Lactation and Breastmilk:Relevant published information was not found as of the revision date.
来源:Drugs and Lactation Database (LactMed)