1-ethyl-5-methyl-1H-benzotriazole

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并三唑类
• 英文名称: 1-ethyl-5-methyl-1H-benzotriazole
• 英文别名: 1-ethyl-5-methyl-1H-benzotriazole；1-Aethyl-5-methyl-1H-benzotriazol；1-Ethyl-5-methylbenzotriazole
• 化学式: C₉H₁₁N₃
• 分子量: 161.206
• InChiKey: FSVLKFCHPABZEB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.9
• 重原子数：
  12
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  30.7
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  N1-乙基-4-甲基-1,2-苯二胺 在 盐酸 、 水 、 sodium nitrite 作用下， 生成 1-ethyl-5-methyl-1H-benzotriazole
  参考文献：
  名称：

  Noelting; Abt, Chemische Berichte, 1887, vol. 20, p. 3001

  摘要：

  DOI：

文献信息

• Reactions of benzotriazoles with diethyl ethoxymethylenemalonate; ethylation and michael addition. Comparison with other esters and<i>N</i>-heterocycles
  作者：Paolo Sanna、Antonio Carta、Giuseppe Paglietti、Alessia Bacchi、Giancarlo Pelizzi

  DOI：10.1002/jhet.5570340117

  日期：1997.1

  Benzotriazole and its 5-methyl-and 5-nitro derivatives react with diethyl ethoxymethylenemalonate by ethylation at each of the ring N-atoms and through Michael addition, to give the isomeric esters ethyl (E/Z) 3-[5(6)-R-benzotriazol-1-yl]propenoates. Benzotriazole and its 5-nitro derivative react similarly with ethyl acetoacetate but N-ethyl derivatives are obtained in lower yields. Other 1,2,3-triazoles

  苯并三唑及其5-甲基和5-硝基衍生物与乙氧基亚甲基丙二酸二乙酯通过在每个环N原子上进行乙基化反应并通过迈克尔加成反应，生成乙基（E / Z）3- [5（6）- R-苯并三唑-1-基]丙烯酸酯。苯并三唑及其5-硝基衍生物与乙酰乙酸乙酯类似地反应，但是以较低的产率获得N-乙基衍生物。其他1,2,3-三唑衍生物和吲哚在该反应中无效，而苯并咪唑产生了相似的结果，但伴随有少量苯并咪唑啉加成产物，其结构已通过晶体学分析确定。
• COMPOUNDS FOR THE TREATMENT OF CANCER AND INFLAMMATORY DISEASE
  申请人：SHY Therapeutics LLC

  公开号：US20170174699A1

  公开（公告）日：2017-06-22

  Provided herein are compounds that inhibit the phosphorylation of MAPK and thus are useful in compositions and methods for treating cancer and inflammatory disease.

  本文提供了抑制MAPK磷酸化的化合物，因此可用于治疗癌症和炎症性疾病的组合物和方法。
• Nonaqueous electrolyte and nonaqueous secondary battery
  申请人：Asahi Kasei Kabushiki Kaisha

  公开号：US10756394B2

  公开（公告）日：2020-08-25

  The purpose of the present invention is to provide a nonaqueous electrolyte that contains acetonitrile having an excellent balance between viscosity and the dielectric constant and a fluorine-containing inorganic lithium salt, wherein the generation of complex cations comprising a transition metal and acetonitrile is suppressed, excellent load characteristics are exhibited, and increases in internal resistance upon repeated charge/discharge cycles are suppressed; a further purpose of the present invention is to provide a nonaqueous secondary battery. The present invention relates to a nonaqueous electrolyte which contains: a nonaqueous solvent comprising acetonitrile; a fluorine-containing inorganic lithium salt; and a specific nitrogenous cyclic compound typified by benzotriazole.

  本发明的目的是提供一种非水电解液，该电解液含有在粘度和介电常数之间具有极佳平衡的乙腈和含氟无机锂盐，其中包含过渡金属和乙腈的复合阳离子的生成受到抑制，显示出极佳的负载特性，并且在重复充放电循环中内阻的增加受到抑制；本发明的另一个目的是提供一种非水二次电池。本发明涉及一种非水电解液，其中包含：由乙腈组成的非水溶剂；含氟无机锂盐；以及以苯并三唑为典型代表的特定含氮环状化合物。
• Antifreeze compositions
  申请人：Choudhary Anil

  公开号：US20090090887A1

  公开（公告）日：2009-04-09

  Disclosed is an antifreeze composition comprising a) a water soluble liquid alcohol freezing point depressant, b) a triazine based compound of formula I, c) a mixture of tolutriazole compounds of formulae II and III, d) 2-ethylhexanoic acid or alkali metal salts thereof, e) heptanoic acid or alkali metal salts thereof and f) water, where the compounds of formula I are where Z is a C 1 -C 11 alkylene group, X is hydrogen or an alkali metal, R 1 and R 2 , independently are hydrogen or methyl, R 3 is a group —NR 4 R 5 where R 4 is C 1 -C 12 alkyl or -Z-COOX and R 5 is hydrogen or C 1 -C 12 alkyl; and where the compounds of formulae II and III are
• COMPOSITION INCLUDING FLUORINE-CONTAINING POLYMER COMPRISING AT LEAST ONE TYPE OF GROUP SELECTED FROM GROUP COMPRISING POLYMERIZABLE FUNCTIONAL GROUPS AND CROSS-LINKABLE FUNCTIONAL GROUPS; AND COATED ARTICLE
  申请人：DAIKIN INDUSTRIES, LTD.

  公开号：US20160168389A1

  公开（公告）日：2016-06-16

  The present invention aims to provide a composition capable of forming a coat which has a good effect of preventing corrosion of metal and is excellent in adhesiveness with metal, transparency, and insulation. The composition of the present invention includes a fluoropolymer having at least one group selected from the group consisting of polymerizable functional groups and cross-linkable functional groups, and a nitrogen-containing aromatic heterocyclic compound having a polymerizable functional group.