(2,4-二硝基苯基)丙-2-烯酸酯 | 62599-74-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚酯
• 中文名称: (2,4-二硝基苯基)丙-2-烯酸酯
• 英文名称: 2,4-dinitrophenyl acrylate
• 英文别名: acrylic acid-(2,4-dinitro-phenyl ester)；Acrylsaeure-(2,4-dinitro-phenylester)；2,4-Dinitrophenylpropenoat；2,4-Dinitrophenylacrylat；2,4-Dinitrophenyl prop-2-enoate；(2,4-dinitrophenyl) prop-2-enoate
• CAS: 62599-74-0
• 化学式: C₉H₆N₂O₆
• 分子量: 238.156
• InChiKey: RKJGQMJOEDIVQQ-UHFFFAOYSA-N

物化性质

• 熔点：
  44-45 °C
• 沸点：
  401.2±38.0 °C(Predicted)
• 密度：
  1.466±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  17
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  118
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  (2,4-二硝基苯基)丙-2-烯酸酯 在 水 作用下， 生成 2,4-二硝基酚 、 丙烯酸
  参考文献：
  名称：

  Marsh, Mary Rose; Gold, Victor; Hall, C. Dennis, Journal of Chemical Research, Miniprint, 1989, # 8, p. 1801 - 1814

  摘要：

  DOI：
• 作为产物：
  描述：

  2,4-二硝基酚 、 丙烯酰氯 在 四氯化碳 、 sodium carbonate 作用下， 生成 (2,4-二硝基苯基)丙-2-烯酸酯
  参考文献：
  名称：

  Lebedew; Andrianowa, Zhurnal Obshchei Khimii, 1955, vol. 25, p. 210,211, 212; engl. Ausg. S. 193

  摘要：

  DOI：

文献信息

• Reductive Bis-addition of Aromatic Aldehydes to α,β-Unsaturated Esters via the Use of Sm/Cu(I) in Air: A Route to the Construction of Furofuran Lignans
  作者：Yongjun Liu、Guang Tian、Jingjing Li、Yan Qi、Yonghong Wen、Feng Du

  DOI：10.1021/acs.joc.7b00278

  日期：2017.6.2

  benzaldehydes to acrylates or maleates was achieved by the direct use of samarium metal with the assistance of CuI under mild conditions under dry air, and the useful 2-hydroxylalkyl-γ-butyrolactons and lignan derivatives were thus constructed with high efficiency. The key factors that influence the reaction efficiency were investigated. The use of potassium iodide and molecular sieves as additives can improve

  在干燥空气中，在温和的条件下，借助CuI在CuI的帮助下直接使用sa金属，可以实现苯甲醛与丙烯酸酯或马来酸酯的新型双加成反应，从而以较高的结构构建了有用的2-羟基烷基-γ-丁内酯和木脂素衍生物。效率。研究了影响反应效率的关键因素。使用碘化钾和分子筛作为添加剂可以显着提高反应效率。
• Coating compositions for preventing adhesion of aquatic organisms
  申请人：KANSAI PAINT CO. LTD.

  公开号：EP0327021A2

  公开（公告）日：1989-08-09

  Disclosed is a coating composition for preventing adhesion of aquatic organisms, the composition containing as a vehicle component a copolymer prepared by copolymerizing about 5 to about 85% by weight of (A) a monohydric and/or polyhydric phenol ester of acrylic or methacrylic acid; about 15 to about 75% by weight of (B) an ethylenically unsaturated monomer having a soluble parameter of about 8.0 to about 9.5 and a glass transition temperature of about 0°C or higher; and about 0 to about 50% by weight of (C) a water-soluble, ethylenically unsaturated monomer containing carboxyl group or amino group, based on the total monomer components.

  公开了一种用于防止水生生物粘附的涂层组合物，该组合物含有作为载体组分的共聚物，该共聚物是通过共聚以下物质制备的：(A)丙烯酸或甲基丙烯酸的单水和/或多水苯酚酯，约5%至约85%(重量)；(B)乙烯基不饱和单体，约15%至约75%(重量)，该乙烯基不饱和单体具有约8.0至约9.5和玻璃化温度约为0℃或更高的乙烯基不饱和单体；以及以单体总组分为基准，约0至约50%(重量)的(C)含羧基或氨基的水溶性乙烯基不饱和单体。
• Methods of immobilizing ligands on solid supports and apparatus and methods of use therefor
  申请人：Matrix Technologies Corporation

  公开号：US20030143570A1

  公开（公告）日：2003-07-31

  A method is provided for immobilizing a ligand, e.g., a nucleic acid, on a solid support. The method includes providing a solid support containing an immobilized latent thiol group, activating the thiol group, contacting the activated thiol group with a nucleic acid comprising an acrylamide functional group, and forming a covalent bond between the two groups, thereby immobilizing the nucleic acid to the solid support. Kits containing the solid supports and method of utilizing the solid supports are also provided.

  提供了一种将配体（如核酸）固定在固体支持物上的方法。该方法包括提供含有固定化潜伏硫醇基团的固体支持物，活化硫醇基团，将活化的硫醇基团与含有丙烯酰胺官能团的核酸接触，并在两个基团之间形成共价键，从而将核酸固定在固体支持物上。还提供了含有固体支持物的试剂盒和利用固体支持物的方法。
• Responsive microgel and methods related thereto
  申请人：——

  公开号：US20030152623A1

  公开（公告）日：2003-08-14

  A responsive microgel is provided which responds volumetrically and reversibly to a change in one or more aqueous conditions selected from the group consisting of (temperature, pH, and ionic conditions) comprised of an ionizable network of covalently cross-linked homopolymeric ionizable monomers wherein the ionizable network is covalently attached to an amphiphilic copolymer to form a plurality of ‘dangling chains’ and wherein the ‘dangling chains’ of amphiphilic copolymer form immobile micelle-like aggregates in aqueous solution. A responsive microgel is further provided that comprises at least one therapeutic entity and delivers a substantially linear and sustained release of the therapeutic entity under physiological conditions.

  本发明提供了一种响应型微凝胶，该微凝胶可对选自由温度、pH 值和离子条件组成的组中的一种或多种水性条件的变化作出体积上和可逆的响应、和离子条件）组成的共价交联均聚可离子化单体的可离子化网络，其中可离子化网络与两性共聚物共价连接，形成多条 "悬链"，两性共聚物的 "悬链 "在水溶液中形成不动的胶束状聚集体。还提供了一种响应性微凝胶，它包含至少一种治疗实体，并能在生理条件下提供治疗实体的线性和持续释放。
• PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS
  申请人：G.D. Searle & Co.

  公开号：EP0907666A1

  公开（公告）日：1999-04-14