尿膽素 | 1856-98-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 四吡咯及其衍生物
• 中文名称: 尿膽素
• 中文别名: 糞膽[色]素；3,18-二乙基-1,4,5,15,16,19,22,24-八氢-2,7,13,17-四甲基-1,19-二氧代-21H-哔啉-8,12-二丙酸
• 英文名称: 3-[2-[[3-(2-carboxyethyl)-5-[(3-ethyl-4-methyl-5-oxo-1,2-dihydropyrrol-2-yl)methyl]-4-methyl-1H-pyrrol-2-yl]methylidene]-5-[(4-ethyl-3-methyl-5-oxo-1,2-dihydropyrrol-2-yl)methyl]-4-methylpyrrol-3-yl]propanoic acid
• CAS: 1856-98-0
• 化学式: C₃₃H₄₂N₄O₆
• 分子量: 590.7
• InChiKey: KDCCOOGTVSRCHX-UHFFFAOYSA-N

物化性质

• 沸点：
  890.5±65.0 °C(Predicted)
• 密度：
  1.32±0.1 g/cm3(Predicted)
• 物理描述：
  Solid

计算性质

• 辛醇/水分配系数(LogP)：
  1.6
• 重原子数：
  43
• 可旋转键数：
  13
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.48
• 拓扑面积：
  161
• 氢给体数：
  5
• 氢受体数：
  7

文献信息

• METHODS OF DIAGNOSING DISEASE
  申请人：4D Pharma Cork Limited

  公开号：EP3947743A1

  公开（公告）日：2022-02-09
• Medical Use of Bilirubin and its Structural Analogues
  申请人：Wang Xiang H.

  公开号：US20080070971A1

  公开（公告）日：2008-03-20

  Formulations and methods for preventing, inhibiting or controlling metabolic disorder, age-related disease and acute inflammations have been developed. The compositions comprise of bilirubins, bilirubin derivatives, their tetrapyrrolic analogues, tripyrroles, and dipyrroles. The compositions can be administered as a dosage form for oral ingestion, injection, suppository, or topical application. The effective amount of the compound is typically from 0.001-100 mg/kg body weight, preferably in the range from 0.01-50 mg/kg body weight, and most preferably from 0.05-10 mg/kg body weight. Examples demonstrate the efficacy of the compounds in both in vitro and in vivo tests.
• [EN] METHODS OF DIAGNOSING DISEASE<br/>[FR] PROCÉDÉS DE DIAGNOSTIC D'UNE MALADIE
  申请人：4D PHARMA CORK LTD

  公开号：WO2020201457A1

  公开（公告）日：2020-10-08

  The application provides new and improved methods for diagnosing IBS.