(3,4-二羟基苯基)-(3,4,5-三羟基苯基)甲酮 | 56609-45-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: (3,4-二羟基苯基)-(3,4,5-三羟基苯基)甲酮
• 英文名称: 3,4,5,3',4'-pentahydroxy-benzophenone
• 英文别名: 3,4,5,3',4'-Pentahydroxy-benzophenon；(3,4-Dihydroxyphenyl)(3,4,5-trihydroxyphenyl)methanone；(3,4-dihydroxyphenyl)-(3,4,5-trihydroxyphenyl)methanone
• CAS: 56609-45-1
• 化学式: C₁₃H₁₀O₆
• 分子量: 262.219
• InChiKey: SPGXHJLVTVJISF-UHFFFAOYSA-N

物化性质

• 熔点：
  266°C
• 沸点：
  672.3±55.0 °C(Predicted)
• 密度：
  1.641±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.5
• 重原子数：
  19
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  118
• 氢给体数：
  5
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  硫酸 、 (3,4-二羟基苯基)-(3,4,5-三羟基苯基)甲酮 生成 原儿茶酸
  参考文献：
  名称：

  Noelting; Meyer,A., Chemische Berichte, 1897, vol. 30, p. 2593

  摘要：

  DOI：
• 作为产物：
  描述：

  没食子酸 、 邻苯二酚 在 zinc(II) chloride 作用下， 生成 (3,4-二羟基苯基)-(3,4,5-三羟基苯基)甲酮
  参考文献：
  名称：

  Noelting; Meyer,A., Chemische Berichte, 1897, vol. 30, p. 2593

  摘要：

  DOI：

文献信息

• [EN] COMPOSITIONS OF POLYHYDROXYLATED BENZOPHENONES AND METHODS OF TREATMENT OF NEURODEGENERATIVE DISORDERS<br/>[FR] COMPOSITIONS DE BENZOPHÉNONES POLYHYDROXYLÉS ET MÉTHODES DE TRAITEMENT DE TROUBLES NEURODÉGÉNÉRATIFS
  申请人：MASSACHUSETTS INST TECHNOLOGY

  公开号：WO2017106861A1

  公开（公告）日：2017-06-22

  The present invention relates to polyhydroxylated benzophenone compounds useful in the treatment of neurodegenerative, neurological, psychiatric, and cognitive diseases, in particular those associated with a deficiency in HDAC1 deacetylase activity.

  本发明涉及聚羟基苯酮类化合物，其在治疗神经退行性、神经学、精神病和认知疾病中有用，特别是那些与HDAC1脱乙酰化酶活性缺乏有关的疾病。
• Powdered epoxy resin compositions
  申请人：MINNESOTA MINING AND MANUFACTURING COMPANY

  公开号：EP0342035A2

  公开（公告）日：1989-11-15

  A powdered coating composition contains an uncured epoxy resin having an epoxy equivalent weight greater than 99, and at least one aromatic compound having hydroxyl groups in adjacent or available adjacent positions. The coating composition is applied to a metal substrate, and is heated to coalesce and cure the composition into a tenacious, anti-corrosive coating.

  一种粉末状涂料组合物含有环氧当量大于 99 的未固化环氧树脂，以及至少一种在相邻或可相邻位置具有羟基的芳香族化合物。将涂料组合物涂在金属基材上，加热使其凝聚并固化成坚韧的防腐蚀涂层。
• Compositions of polyhydroxylated benzophenones and methods of treatment of neurodegenerative disorders
  申请人：Massachusetts Institute of Technology

  公开号：US11180438B2

  公开（公告）日：2021-11-23

  The present invention relates to polyhydroxylated benzophenone compounds useful in the treatment of neurodegenerative, neurological, psychiatric, and cognitive diseases, in particular those associated with a deficiency in HDAC1 deacetylase activity.

  本发明涉及多羟基二苯甲酮化合物，可用于治疗神经退行性疾病、神经疾病、精神疾病和认知疾病，特别是与 HDAC1 去乙酰化酶活性缺乏有关的疾病。
• Resist underlayer film-forming composition
  申请人：NISSAN CHEMICAL CORPORATION

  公开号：US11287741B2

  公开（公告）日：2022-03-29

  A composition for forming a resist underlayer film that functions as an anti-reflective coating during exposure and can be embedded in a recess having a narrow space and a high aspect ratio, and has excellent resistance to an aqueous hydrogen peroxide solution. A resist underlayer film-forming composition containing a resin, a compound of the following Formula (1a) or (1b): wherein X is carbonyl group or methylene group, 1 and m are each independently an integer of 0 to 5 and satisfy a relational expression of 3≤1+m 10, and n is an integer of 2 to 5, and a solvent, wherein the compound of Formula (1a) or (1b) is contained in an amount of 0.01% by mass to 60% by mass relative to the amount of the resin.

  一种用于形成抗蚀剂底层膜的组合物，该抗蚀剂底层膜在曝光时可用作抗反射涂层，并可嵌入具有窄空间和高长宽比的凹槽中，而且对过氧化氢水溶液具有优异的耐受性。抗蚀剂底层成膜组合物含有树脂、下式（1a）或（1b）的化合物： 其中 X 是羰基或亚甲基，1 和 m 各自独立地为 0 至 5 的整数，且满足 3≤1+m 10 的关系式，n 是 2 至 5 的整数，以及溶剂，其中式 (1a) 或 (1b) 化合物的含量为树脂含量的 0.01% 至 60%。
• COMPOSITIONS OF POLYHYDROXYLATED BENZOPHENONES AND METHODS OF TREATMENT OF NEURODEGENERATIVE DISORDERS
  申请人：Massachusetts Institute of Technology

  公开号：US20200087236A9

  公开（公告）日：2020-03-19

  The present invention relates to polyhydroxylated benzophenone compounds useful in the treatment of neurodegenerative, neurological, psychiatric, and cognitive diseases, in particular those associated with a deficiency in HDAC1 deacetylase activity.