(3-溴苯基)(4-甲基哌嗪-1-基)甲酮 | 331274-67-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: (3-溴苯基)(4-甲基哌嗪-1-基)甲酮
• 英文名称: (3-Bromophenyl)(4-methylpiperazin-1-yl)methanone
• 英文别名: (3-bromophenyl)-(4-methylpiperazin-1-yl)methanone
• CAS: 331274-67-0
• 化学式: C₁₂H₁₅BrN₂O
• mdl: MFCD00594888
• 分子量: 283.16
• InChiKey: UWDFKAKQJOXLHT-UHFFFAOYSA-N

物化性质

• 沸点：
  386.3±37.0 °C(Predicted)
• 密度：
  1.403±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1
• 重原子数：
  16
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.416
• 拓扑面积：
  23.6
• 氢给体数：
  0
• 氢受体数：
  2

安全信息

• 危险性防范说明：
  P261,P305+P351+P338
• 危险性描述：
  H302,H315,H319,H335

文献信息

• PYRROLO [2, 3-D]PYRIDINES AND USE THEREOF AS TYROSINE KINASE INHIBITORS
  申请人：Novartis AG

  公开号：EP2247591A1

  公开（公告）日：2010-11-10
• [EN] PYRROLO [2, 3-D] PYRIDINES AND USE THEREOF AS TYROSINE KINASE INHIBITORS<br/>[FR] COMPOSÉS HÉTÉROCYCLIQUES
  申请人：NOVARTIS AG

  公开号：WO2009098236A1

  公开（公告）日：2009-08-13

  The invention relates to compounds of formula (I) and salts thereof formula (I), wherein the substituens are as defined in the specification, processes for the preparation thereof; to pharmaceuticals containing such compounds, in particular for the use in one or more Protein tyrosine kinase mediated diseases.
• [EN] THERAPEUTIC ANTIVIRAL PEPTIDES<br/>[FR] PEPTIDES ANTIVIRAUX THÉRAPEUTIQUES
  申请人：INTERMUNE INC

  公开号：WO2012047764A1

  公开（公告）日：2012-04-12

  The invention relates to compounds of Formula (I) (in which the variables are defined as herein) and compositions, including pharmaceutical compositions, thereof. The invention further provides treatment methods, including methods of treating a hepatitis C virus infection and methods of treating liver fibrosis through administering to an individual in need thereof an effective amount of a subject compound or composition.