布他沙明 | 2922-20-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 布他沙明
• 中文别名: alpha-[1-[(1,1-二甲基乙基)氨基]乙基]-2,5-二甲氧基-苯甲醇
• 英文名称: butoxamine
• 英文别名: butaxamine；2-(tert-butylamino)-1-(2,5-dimethoxyphenyl)propan-1-ol
• CAS: 2922-20-5
• 化学式: C₁₅H₂₅NO₃
• 分子量: 267.368
• InChiKey: TWUSDDMONZULSC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  19
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.6
• 拓扑面积：
  50.7
• 氢给体数：
  2
• 氢受体数：
  4

安全信息

• 海关编码：
  2922509090

文献信息

• Enantioselective zwitterionic ion-exchange material
  申请人：UNIVERSITAET WIEN

  公开号：US10265644B2

  公开（公告）日：2019-04-23

  An enantioselective zwitterionic ion-exchange material comprising a chiral selector component (SO) comprising at least one cation exchange group and at least one anion exchange group and a carrier, carrying said selector component, wherein the chiral selector component comprises at least one chiral linker moiety to connect said ion exchange groups in a non-macrocyclic fashion, and said chiral linker moiety contains at least one π-π interaction site.

  一种对映体选择性齐聚离子交换材料，包括由至少一个阳离子交换基团和至少一个阴离子交换基团组成的手性选择组分（SO）以及携带所述选择组分的载体，其中 手性选择成分包括至少一个手性连接分子，用于以非大环方式连接所述离子交换基团，以及 所述手性连接分子包含至少一个 π-π 相互作用位点。
• New derivatives of 1-alkylamine-(4(p-alkyloxy-benzamide)phenoxy)-2-propanol, having beta-sympatholytic activity, their salts, and production processes thereof
  申请人：A. Menarini S.a.S.

  公开号：EP0100051B1

  公开（公告）日：1986-04-09
• ENANTIOSELECTIVE ZWITTERIONIC ION-EXCHANGE MATERIAL
  申请人：Lindner Wolfgang

  公开号：US20110121229A1

  公开（公告）日：2011-05-26

  An enantioselective zwitterionic ion-exchange material comprising a chiral selector component (SO) comprising at least one cation exchange group and at least one anion exchange group and a carrier, carrying said selector component, wherein the chiral selector component comprises at least one chiral linker moiety to connect said ion exchange groups in a non-macro-cyclic fashion, and said chiral linker moiety contains at least one π-π interaction site.
• SIGMA-1 RECEPTOR AGONIST SYSTOLIC BLOOD PRESSURE THERAPY
  申请人：ANAVEX LIFE SCIENCES CORP.

  公开号：US20210186920A1

  公开（公告）日：2021-06-24

  A method for lowering systolic blood pressure in a patient exhibiting resistance to a antihypertensive therapy with one or more drugs, the method comprising administering to the patient ANAVEX®2-73 at a dose and frequency effective to provide a reduction of at least about 3 mmHg in one or more blood pressure parameters selected from trough sitting systolic, 24-hour ambulatory systolic, and maximum diurnal systolic blood pressures.
• US3937834A
  申请人：——

  公开号：US3937834A

  公开（公告）日：1976-02-10