(4-膦基苯基)膦 | 78550-67-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: (4-膦基苯基)膦
• 英文名称: 1,4-diphosphanobenzene
• 英文别名: 1,4-diphosphinobenzene；p-phenylenediphosphine；p-Phenylen-diphosphin；Phosphine, 1,4-phenylenebis-；(4-phosphanylphenyl)phosphane
• CAS: 78550-67-1
• 化学式: C₆H₈P₂
• 分子量: 142.077
• InChiKey: DXKIVDBWRHJILG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1
• 重原子数：
  8
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

安全信息

• 海关编码：
  2902909090

反应信息

• 作为反应物：
  描述：

  tris[triphenylphosphinegold(I)]oxonium tetrafluoroborate 、 (4-膦基苯基)膦 以 二氯甲烷 为溶剂， 以90%的产率得到
  参考文献：
  名称：

  Schmidbaur, Hubert; Zeller, Edgar; Ohshita, Joji, Inorganic Chemistry, 1993, vol. 32, # 21, p. 4524 - 4526

  摘要：

  DOI：
• 作为产物：
  描述：

  p-phenylenebis-(magnesium bromide) 在 lithium aluminium tetrahydride 、 chlorinating agent 作用下， 生成 (4-膦基苯基)膦
  参考文献：
  名称：

  UPE studies of conjugation involving Group 5A elements. 1. Phenylphosphines

  摘要：

  DOI：

  10.1021/ja00402a009

文献信息

• Alkyl Group VA metal compounds
  申请人：Shipley Company, L.L.C.

  公开号：US20030181746A1

  公开（公告）日：2003-09-25

  Disclosed are methods of preparing monoalkyl Group VA metal dihalide compounds in high yield and high purity by the reaction of a Group VA metal trihalide with an organo lithium reagent or a compound of the formula R n M 1 X 3−n , where R is an alkyl, M 1 is a Group IIIA metal, X is a halogen and n is an integer fro 1 to 3. Such monoalkyl Group VA metal dihalide compounds are substantially free of oxygenated impurities, ethereal solvents and metallic impurities. Monoalkyl Group VA metal dihydride compounds can be easily produced in high yield and high purity by reducing such monoalkyl Group VA metal dihalide compounds.

  揭示了通过将VA族金属三卤化物与有机锂试剂或具有公式RnM1X3−n的化合物（其中R是烷基，M1是III A族金属，X是卤素，n是1到3的整数）反应，以高产率和高纯度制备单烷基VA族金属二卤化合物的方法。这种单烷基VA族金属二卤化合物基本上不含氧杂质、醚溶剂和金属杂质。通过还原这种单烷基VA族金属二卤化合物，可以轻松地高产率和高纯度地生产单烷基VA族金属二氢化合物。
• [EN] NOVEL DIAZAPHOSPHOLANE LIGANDS FOR ASYMMETRIC CATALYSIS<br/>[FR] NOUVEAUX LIGANDS DIAZAPHOSPHOLANE POUR CATALYSE ASYMETRIQUE
  申请人：DOW CHEMICAL CO

  公开号：WO2006026489A1

  公开（公告）日：2006-03-09

  This invention relates to a asymmetric hydroformylation processes in which a prochiral or chiral olefin is reacted with carbon monoxide and hydrogen in the presence of an optically active metal-ligand complex catalyst to produce an optically active aldehyde or a product derived from an optically active aldehyde.

  这项发明涉及一种不对称氢甲酰化过程，其中一个原手性或手性烯烃在存在光学活性金属配体复合催化剂的情况下与一氧化碳和氢反应，产生一个光学活性醛或源自光学活性醛的产物。
• Alkyl group VA metal compounds
  申请人：Shenai-Khatkhate Vinayak Deodatta

  公开号：US20050033073A1

  公开（公告）日：2005-02-10

  A method of preparing Group VA organometal compounds in high yield and high purity by the reaction of a Grignard reagent with a Group VA metal halide in certain ethereal solvents is provided. A method of preparing Group VA organometal hydrides is also provided.

  提供了一种通过格氏试剂与VA族金属卤化物在特定的醚溶剂中反应制备高收率和高纯度VA族有机金属化合物的方法。还提供了一种制备VA族有机金属氢化物的方法。
• Preparation of monoalkyl group 15 metal dihalides and dihydrides
  申请人：Shipley Co. L.L.C.

  公开号：EP1335416A1

  公开（公告）日：2003-08-13

  Disclosed are methods of preparing monoalkyl Group VA metal dihalide compounds in high yield and high purity by the reaction of a Group VA metal trihalide with an organo lithium reagent or a compound of the formula RnM1X3-n where R is an alkyl, M1 is a Group IIIA metal, X is a halogen and n is an integer fro 1 to 3. Such monoalkyl Group VA metal dihalide compounds are substantially free of oxygenated impurities, ethereal solvents and metallic impurities. Monoalkyl Group VA metal dihydride compounds can be easily produced in high yield and high purity by reducing such monoalkyl Group VA metal dihalide compounds.

  公开了通过 VA 族金属三卤化物与有机锂试剂或式 RnM1X3-n 的化合物反应制备高产率和高纯度的单烷基 VA 族金属二卤化物化合物的方法，其中 R 为烷基，M1 为 IIIA 族金属，X 为卤素，n 为 1 至 3 的整数。通过还原这种单烷基 VA 族金属二卤化物化合物，可以很容易地生产出高产率和高纯度的单烷基 VA 族金属二氢化物化合物。
• AMINOTETRAHYDROPYRAN DERIVATIVE USED AS DIPEPTIDYL PEPTIDASE-IV INHIBITOR
  申请人：FUJIAN BORO MEDICAL CO., LTD.

  公开号：EP3144310A1

  公开（公告）日：2017-03-22

  Provided is an Aminotetrahydropyran derivative represented by general formula (I), a preparation method for the derivative, a pharmaceutical composition containing the derivative, and the use of the derivative to prepare a therapeutic agent, especially a dipeptidyl peptidase-IV inhibitor.

  本发明提供了由通式（I）表示的氨基四氢吡喃衍生物、该衍生物的制备方法、含有该衍生物的药物组合物，以及使用该衍生物制备治疗剂，特别是二肽基肽酶-IV 抑制剂。