(9ci)-5-丁基-1H-苯并咪唑-2-胺 | 30486-72-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并咪唑类
• 中文名称: (9ci)-5-丁基-1H-苯并咪唑-2-胺
• 英文名称: 2-Amino-5(6)-n-butylbenzimidazol
• 英文别名: 5-butyl-1(3)H-benzoimidazol-2-ylamine；5-butyl-2-aminobenzimidazole；Benzimidazole, 2-amino-5-butyl-；6-butyl-1H-benzimidazol-2-amine
• CAS: 30486-72-7
• 化学式: C₁₁H₁₅N₃
• mdl: MFCD01744883
• 分子量: 189.26
• InChiKey: DDILIJVAQMXPMR-UHFFFAOYSA-N

物化性质

• 沸点：
  314.52°C (rough estimate)
• 密度：
  1.1069 (rough estimate)

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  14
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.363
• 拓扑面积：
  54.7
• 氢给体数：
  2
• 氢受体数：
  2

安全信息

• 海关编码：
  2933990090

制备方法与用途

类别：有毒物品

可燃性危险特性：

• 可燃；燃烧产生有毒氮氧化物烟雾

储运特性：

• 库房需通风、低温干燥

灭火剂：

• 干粉、泡沫、砂土、二氧化碳，以及雾状水

文献信息

• Method for reducing a susceptibility to tumor formation induced by 3-deoxyglucosone and precursors thereof
  申请人：Brown R. Truman

  公开号：US20060089316A1

  公开（公告）日：2006-04-27

  Disclosed are methods of using various compounds, which are known to bind to 3-deoxyglucosone (3DG) or precursors thereof, in order to reduce a susceptibility to tumor formation and/or to prevent or delay onset of tumor formation induced by 3DG and its precursors. Also disclosed is the reduction of 3DG levels in high fructose corn syrop so that the high fructose corn syrup is less likely to induce tumor formation.

  公开了使用各种已知与3-脱氧葡萄糖酮（3DG）或其前体结合的化合物的方法，以减少对肿瘤形成的易感性和/或预防或延迟由3DG及其前体诱导的肿瘤形成。还公开了降低高果糖玉米糖浆中3DG水平的方法，以使高果糖玉米糖浆不太可能诱导肿瘤形成。
• HERPES VIRUS-BASED COMPOSITIONS AND METHODS OF USE IN THE PRENATAL AND PERINATAL PERIODS
  申请人：THE UNIVERSITY OF ROCHESTER

  公开号：EP1903873A2

  公开（公告）日：2008-04-02
• Herpes Virus-Based Compositions and Methods of Use in the Prenatal and Perinatal Periods
  申请人：Federoff Howard J.

  公开号：US20080226601A1

  公开（公告）日：2008-09-18

  Disclosed are compositions and methods for reducing the severity of a birth defect in a mammal by exposing the mammal (e.g., in utero) to a herpes virus amplicon particle comprising a cis element-flanked transgene and a sequence encoding a transposase. Upon expression, the transposase inserts the transgene into the genome of a cell (e.g., a neuron) within the mammal and the transgene expresses a polypeptide or RNA that compensates for a protein or gene defect that is causally associated with the birth defect.
• METHODS TO ACCELERATE THE ISOLATION OF NOVEL CELL STRAINS FROM PLURIPOTENT STEM CELLS AND CELLS OBTAINED THEREBY
  申请人：West Michael D.

  公开号：US20100184033A1

  公开（公告）日：2010-07-22

  Aspects of the present invention relate to methods to differentiate pluripotent primordial stem cells, such as human embryonic stem (“hES”) cells, human embryonic germ (“hEG”) cells, human embryo-derived (“hED”) cells and human embryonal carcinoma (“hEC”) cells, to obtain subpopulations of cells from heterogeneous mixtures of cells, wherein the subpopulation of cells possess reduced differentiation potential compared to the original pluripotent stem cells and where the subpopulation is capable of being propagated 20 or more population doublings. This invention also provides novel compositions of such subpopulations of cells and methods to propagate and differentiate said cells.
• US5326779A
  申请人：——

  公开号：US5326779A

  公开（公告）日：1994-07-05